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CD24

概要

Name:Signal transducer CD24
Target Synonym:Small cell lung carcinoma cluster 4 antigen,CD24A,CD24 Antigen (Small Cell Lung Carcinoma Cluster 4 Antigen),CD24 Molecule,CD24 Antigen
Number of Launched Drugs:0
Number of Drugs in Clinical Trials:2
Lastest Research Phase:Phase 1 Clinical

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ACRO Quality

生物活性データの一部

CD4-H5257-ELISA
 CD24 ELISA

Immobilized Human CD24, Mouse IgG2a Fc Tag (Cat. No. CD4-H5257) at 5 μg/mL (100 μL/well) can bind Anti-CD24 MAb (SN3) with a linear range of 20-313 ng/mL (QC tested).

CD4-H52H5-ELISA
 CD24 ELISA

Immobilized Human CD24 Protein, His Tag (Cat. No. CD4-H52H5) at 5 μg/mL (100 μL/well) can bind Anti-CD24 MAb (SN3) with a linear range of 5-78 ng/mL (QC tested).

Synonym Name

CD24,CD24A

Background

CD24 may have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity.

Clinical and Translational Updates

臨床試験情報

Name Research Code Research Phase Company Indications Clinical Trials
ATG-031 ATG-031 Phase 1 Clinical Antengene Corporation Co Ltd Hematologic Neoplasms; Solid tumours; Lymphoma, B-Cell Details

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