IL-2 R beta & IL-2 R gamma 詳細
Molecule Name
Interleukin-2 receptor subunit gamma
分子の別称
IL-2 R beta & IL-2 R gamma,IL-2RB & IL-2RG
Drug Development Progress
治験薬の数14
市販薬剤の数0
研究＆開発段階Phase 2 Clinical
ターゲットの別称
Common Cytokine Receptor Gamma Chain，IL-2R Subunit Gamma，IL2RG，SCIDX，CD132，CIDX，IL-2RG，IMD4，Nonfunctional Common Cytokine Receptor Gamma Chain，Combined Immunodeficiency， X-Linked，Interleukin 2 Receptor Subunit Gamma，Interleukin-2 Receptor Subunit Gamma，Severe Combined Immunodeficiency，Cytokine Receptor Common Subunit Gamma，CD132 Antigen，GammaC，Interleukin 2 Receptor， Gamma，IL-2 Receptor Subunit Gamma，SCIDX1，P64
バックグランド
Both Interleukin-2 receptor subunit beta and Interleukin-2 receptor subunit gamma are receptor for interleukin-2. Common subunit for the receptors for a variety of interleukins. Interacts with SHB upon interleukin stimulation. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.
IL-2 R beta & IL-2 R gamma 製品リスト
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E***e2021-09-06We purchased this protein for BLI/SPR analysis. We got the fast and applicable support from Acrobiosystems for our SPR experiment.