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Monoclonal Anti-HRSV F-hRSV90 Antibody, Human IgG1 (MALS verified)

COADS MS
DS

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製品番号/仕様
価格
数量
HRV-M720-100ug
$415.00
HRV-M720-1mg
$2735.00
ETA of in-stock products:2 business days
総アイテム数 製品金額$ 0
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製品詳細

  • Source

    Monoclonal Anti-HRSV F-hRSV90 Antibody, Human IgG1 is a recombinant chimeric monoclonal antibody expressed in HEK293, which combines the variable region of a mouse monoclonal antibody with human constant domain.

  • Antibody Type

    Recombinant Monoclonal

  • Clone

    hRSV90

  • Isotype

    Human IgG1, Kappa

  • Specificity

    This product is a specific antibody specifically reacts with HRSV F.

  • Application

    Application
    Recommended Usage
    ELISA
    0.2-2 μg/mL

  • Purification

    Protein A purified / Protein G purified.

  • Aggregation

    Less than 5%, as determined by SEC-MALS.

  • Concentration

    Please refer to the Certificate of Analysis (CoA).

  • Form

    Liquid

  • Formulation

    Supplied a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 12 months under sterile conditions.

  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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データ表示

  • Bioactivity-ELISA

    Prefusion glycoprotein F0/pre-F protein (RSV) ELISA

    Immobilized HRSV (A) Pre-fusion glycoprotein F0, His Tag (Cat. No. RSF-V52H7) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-HRSV F-hRSV90 Antibody, Human IgG1 (Cat. No. HRV-M720) with a linear range of 0.03-1 ng/mL. HRSV (A) Post-fusion glycoprotein F0, His Tag (Cat. No. RSF-V52H6) is verified not recoginized by Monoclonal Anti-HRSV F-hRSV90 Antibody, Human IgG1 (Cat. No. HRV-M720) in low concentration (QC tested).

    Protocol

  • Prefusion glycoprotein F0/pre-F protein (RSV) ELISA

    Immobilized HRSV (B) Pre-fusion glycoprotein F0, His Tag (Cat. No. RSF-V52H8) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-HRSV F-hRSV90 Antibody, Human IgG1 (Cat. No. HRV-M720) with a linear range of 0.03-1 ng/mL. HRSV (B) Post-fusion glycoprotein F0, His Tag (Cat. No. RSF-V52H9) is verified not recoginized by Monoclonal Anti-HRSV F-hRSV90 Antibody, Human IgG1 (Cat. No. HRV-M720) in low concentration (Routinely tested).

    Protocol

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バックグランド

Human respiratory syncytial virus (HRSV) is the most common etiological agent of acute lower respiratory tract disease in infants and can cause repeated infections throughout life. The RSV fusion glycoprotein (RSV F) is the principal target of RSV neutralizing antibodies in human sera. The RSV F is a type I viral fusion protein synthesized as inactive, single‑chain polypeptides that assemble into trimers. RSV F fuses the viral and host cell membranes by irreversible protein refolding from the labile prefusion conformation to the stable post‑fusion conformation. The antibody hRSV90 recognizes a prefusion‑specific epitope encompassing residues 163–181 within antigenic site V on the RSV F protein.

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