Human ANGPTL7 / CDT6 Protein, His Tag

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製品番号/仕様
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数量
AN7-H52H3-100ug
$420.00
In Stock - Delivery in 2-3 business days
AN7-H52H3-1mg
$3060.00
In Stock - Delivery in 2-3 business days
総アイテム数 製品金額$ 0

製品詳細

  • Synonyms

    ANGPTL7, CDT6

  • Source

    Human ANGPTL7 Protein, His Tag (AN7-H52H3) is expressed from human 293 cells (HEK293). It contains AA Gln 27 - Pro 346 (Accession # O43827-1).

    Request for sequence
  • Molecular Characterization

    ANGPTL7 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 39.0 kDa. The protein migrates as 48-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

    The protein is designed as a trimer.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Supplied as 0.2 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Shipping and Storage

    This product is supplied and shipped on dry ice.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. The product MUST be stored at -70°C or lower upon receipt;
    2. -70°C for 3 months under sterile conditions.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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データ表示

  • SDS-PAGE

    ANGPTL7 SDS-PAGE

    Human ANGPTL7 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    ANGPTL7 SEC-MALS

    The purity of Human ANGPTL7 Protein, His Tag (Cat. No. AN7-H52H3) is more than 90% and the molecular weight of this protein is around 130-160 kDa verified by SEC-MALS.

    Report
  • Bioactivity-SPR

     ANGPTL7 SPR

    Cynomolgus LILRB4, His Tag (Cat. No. CDK-C5227) immobilized on CM5 Chip can bind Human ANGPTL7 Protein, His Tag (Cat. No. AN7-H52H3) with an affinity constant of 0.792 μM as determined in a SPR assay (Biacore 8K) (Routinely tested).

    Protocol

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バックグランド

Angiopoietin-like 7 (ANGPTL7) is also known as Corneal-Derived Transcript 6 (CDT6), and is a secreted glycoprotein that is structurally related to the angiopoietins. It is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor. Recently, ANGPTL proteins, including ANGPTL-2, -3, -4, -5 and -7, are identified as growth factors in combination with SCF, Thrombopoietin, IGF-II and FGF acidic that enhance the expansion and engraftment of human and mouse hematopoietic stem cells.

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