Mouse Cadherin-3 Protein, His Tag

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製品番号/仕様
価格
数量
CA3-M52H3-100ug
$410.00
CA3-M52H3-1mg
$2625.00
ETA of in-stock products:2 business days
総アイテム数 製品金額$ 0

製品詳細

  • Synonyms

    CDH3, CDHP, Cadherin-3, P-cadherin

  • Source

    Mouse Cadherin-3 Protein, His Tag (CA3-M52H3) is expressed from human 293 cells (HEK293). It contains AA Glu 100 - Gly 647 (Accession # P10287).

    Predicted N-terminus: Glu 100

    Request for sequence
  • Molecular Characterization

    Cadherin-3 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the C-terminus.

    The protein has a calculated MW of 62.3 kDa. The protein migrates as 53-55 kDa and 70-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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データ表示

  • SDS-PAGE

    Cadherin-3 SDS-PAGE

    Mouse Cadherin-3 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).

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バックグランド

Cadherin-3 (CDH3), also known as P-Cadherin, is a classical cadherin that functions as a calcium-dependent glycoprotein mediating cell-cell adhesion. Structurally, it is characterized by five extracellular cadherin repeats, a single transmembrane domain, and a highly conserved cytoplasmic tail. The CDH3 gene resides within a cadherin cluster on chromosome 16q, a genomic region linked to loss of heterozygosity in breast and prostate cancer. Furthermore, aberrant expression of the protein is implicated in the pathology of cervical adenocarcinoma.

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医薬品開発の進捗
  • 英語名:

    Cadherin 3

  • カテゴリ:

  • 市販の医薬品数:

    0 詳細

  • 治験医薬品数:

    7 詳細

  • 最新の開発ステージ:

    Phase 2 Clinical

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