PE-Labeled Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Tetramer Protein

ユーザーレビュー
製品番号/仕様
価格
Availability
数量
HLM-HP2H8-25ug
$410.00
In Stock - Delivery in 2-3 business days
HLM-HP2H8-200ug (100ug X 2)
$2350.00
In Stock - Delivery in 2 weeks
総アイテム数 製品金額$ 0

製品詳細

  • Synonyms

    HLA-A*0201 & B2M & MAGE-A10 (GLYDGMEHL)

  • Source

    PE-Labeled Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Tetramer Protein (HLM-HP2H8) is expressed from human 293 cells (HEK293). It contains AA Gly 25 - Ile 308 (HLA-A*02:01) & Ile 21 - Met 119 (B2M) & GLYDGMEHL peptide (Accession # AAA59606.1 (HLA-A*02:01) & P61769 (B2M) & GLYDGMEHL).

    Predicted N-terminus: Gly 25 & Ile 21

    Request for sequence
  • Molecular Characterization

    PE-Labeled Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Tetramer Protein is assembled by biotinylated monomer (HLM-H82Ec) and PE-labeled streptavidin.

    Biotinylated Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Complex Protein is produced by co-expression of HLA and B2M loaded with MAGE-A10 peptide. Biotinylated Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Complex Protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™).

  • Conjugate

    PE

    Excitation Wavelength: 488 nm / 561 nm

    Emission Wavelength: 575 nm

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, 1% BSA, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Shipping and Storage

    This product is shipped at ambient temperature.

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please protect from light and avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

お客様はこちらも閲覧

データ表示

  • Bioactivity-ELISA

     HLA-A*0201 & B2M & MAGE-A10 (GLYDGMEHL) ELISA

    Immobilized PE-Labeled Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Tetramer Protein (Cat. No. HLM-HP2H8) at 1 μg/mL (100 μL/well) can bind Anti-HLA class I Antibody, Human IgG1 (W6/32) with a linear range of 0.1-4 ng/mL (QC tested).

    Protocol
  •  HLA-A*0201 & B2M & MAGE-A10 (GLYDGMEHL) ELISA

    Immobilized PE-Labeled Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Tetramer Protein (Cat. No. HLM-HP2H8) at 1 μg/mL (100 μL/well) can bind Anti-B2M Antibody, Human IgG1 with a linear range of 0.06-2 ng/mL (Routinely tested).

    Protocol

ユーザーレビュー
コメントを投稿

バックグランド

Melanoma-associated antigen A10 (MAGE-A10) is a cancer/testis protein associated with many cancers. MAGE-A10 is overexpressed in cancer cells. The repression of MAGE-A10 expression increased cell-cell and cell matrix adhesion. The Human HLA-A*0201 MAGE-A10 (GLYDGMEHL) complex protein is a complex of HLA-A*0201 of the MHC Class I, B2M and GLYDGMEHL peptide of the MAGE-A10.

最新の進展

 
お問い合わせ
医薬品候補ライセンス
他の関連情報
  • 製品情報
  • 製品詳細
  • お客様はこちらも閲覧
  • データ表示
  • ユーザーレビュー
  • 背景
お問い合わせ

お問い合わせ
グローバル:+1 800-810-0816(Toll Free)

メールアドレス
order.jp@acrobiosystems.com

アクロバイオシステムズ株式会社
〒101-0051
東京都千代田区神田神保町1-32-8