Mouse IL-2 R beta&IL-2 R alpha&IL-2 R gamma Protein, Fc Tag&Fc Tag

Synonyms

IL-2 R beta & IL-2 R alpha & IL-2 R gamma

Source

Mouse IL-2RB&IL-2RA&IL-2RG, Fc Tag&Fc Tag (ILG-M5253) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Glu 240 & Glu 22 - Lys 236 & Trp 23 - Ala 263 (Accession # P16297-1 (IL-2RB) & P01590-1 (IL-2RA) & P34902-1 (IL-2RG)).

Predicted N-terminus: Ala 27 & Glu 22

Molecular Characterization

Mouse IL-2RB&IL-2RA&IL-2RG, Fc Tag&Fc Tag is produced by co-expression of IL-2RB and IL-2RA and IL-2RG, has a calculated MW of 51.5 kDa (IL-2RB) and 79.4 kDa (IL-2RA&IL-2RG). Subunit IL-2RB is fused with a human IgG1 Fc tag at the C-terminus and subunit IL-2RA&IL-2RG is fused with a human IgG1 Fc tag at the C-terminus. The reducing (R) protein migrates as 75-90 kDa and 120-150 kDa when calibrated against Star Ribbon Pre-stained Protein Marker respectively due to glycosylation.

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>95% as determined by SDS-PAGE.

Formulation

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

After reconstitution, this product is stable after storage at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

1. -20°C to -70°C for 12 months in lyophilized state;
2. -70°C for 3 months under sterile conditions after reconstitution.

ACRO Quality Management System

1. QMS(ISO, GMP)
2. Quality Advantages
3. Quality Control Process