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Human MMP-7 / PUMP1 Protein, His Tag (Pro-form)

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MM7-H5249-50ug
$360.00
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MM7-H5249-1mg
$2,225.00
In Stock - Delivery in 1-2 business days
MM7-H5249
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Product Details
Performance Data
Reviews & Citations
Resources
  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
Synonyms

MMP7, Matrilysin, Matrin, MPSL1, PUMP1

Source

Human MMP-7, His Tag (MM7-H5249) is expressed from human 293 cells (HEK293). It contains AA Leu 18 - Lys 267 (Accession # P09237-1). It needs to be activated by agents such as APMA in vitro to have hydrolytic activity.

Predicted N-terminus: Leu 18

Molecular Characterization
Other Tags and Version Biotin & Other Labeled Version

This protein carries a polyhistidine tag at the N-terminus.

The protein has a calculated MW of 30.0 kDa. The protein migrates as 30 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>90% as determined by SDS-PAGE.

Formulation

Supplied as 0.2 μm filtered solution in 10 mM HEPES,150 mM NaCl,pH7.5 with glycerol as protectant.

Contact us for customized product form or formulation.

Shipping and Storage

This product is supplied and shipped on dry ice.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • The product MUST be stored at -70°C or lower upon receipt;
  • -70°C for 3 months under sterile conditions.
ACRO Quality Management System

Background

Matrix metalloproteinase-7（MMP-7）also known as neutrophil collagenase and CLG1，is a member of matrix metalloproteinases (MMPs) family，which degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes as well as pathological processes. MMP-7 may affect the metastatic behavior of breast cancer cells through protection against lymph node metastasis, underlining the importance of anti-target identification in drug development. MMP-7 in the tumor may have a protective effect against lymph node metastasis.