Bat coronavirus hCoV-19/bat/Yunnan/RmYN02/2019 Spike Trimer Protein (R640A, KV940-941PP), His Tag

製品番号/仕様
価格
Availability
数量
SPN-B52H3-50ug
$465.00
In Stock - Delivery in 1-2 business days
SPN-B52H3-500ug (250ug X 2)
$3,170.00
In Stock - Delivery in 1-2 business days
SPN-B52H3
製品金額 :
$ 0
推奨新製品 Request Quote
Contact Us
Contact Us
製品金額:
$ 0
  • 製品詳細
  • データ表示
  • Reviews & Citations
  • Important Statement
  • Resources
Synonyms

Spike, S protein, Spike glycoprotein, S glycoprotein

Source

Bat coronavirus hCoV-19/bat/Yunnan/RmYN02/2019 Spike Trimer, His Tag (SPN-B52H3) is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. It contains AA Ala 11 - Pro 1167 (Accession # EPI_ISL_412977 (R640A, KV940-941PP)).

Predicted N-terminus: Ala 11

Molecular Characterization

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 132.5 kDa. The protein migrates as 150-180 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>95% as determined by SDS-PAGE.

Formulation

Lyophilized from 0.22 μm filtered solution in 0.1 M Sodium citrate, pH5.5 with trehalose as protectant.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.

バックグランド

The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.