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Gastrin-71

Gastrin-71 Overview

English Name	Gastrins	Approved Drugs	0
Drugs in Clinical Trials	0	Target Synonym	Gastrins
Highest Development Stage	Discontinued

English Name	Gastrins
Target Synonym	Gastrins
Approved Drugs	0
Drugs in Clinical Trials	0
Highest Development Stage	Discontinued

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Gastrin-71 Background

Gastrin is a peptide hormone that stimulates secretion of gastric acid (HCl) by the parietal cells of the stomach and aids in gastric motility. It is released by G cells in the pyloric antrum of the stomach, duodenum, and the pancreas. Gastrin binds to cholecystokinin B receptors to stimulate the release of histamines in enterochromaffin-like cells, and it induces the insertion of K+/H+ ATPase pumps into the apical membrane of parietal cells (which in turn increases H+ release into the stomach cavity). Its release is stimulated by peptides in the lumen of the stomach.