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NF-κB

NF-κB 詳細

英語名	Nuclear factor NF-kappa-B complex	市販薬剤の数	12
治験薬の数	39	ターゲットの別称	NF-kappa B
研究＆開発段階	Approved

英語名	Nuclear factor NF-kappa-B complex
ターゲットの別称	NF-kappa B
市販薬剤の数	12
治験薬の数	39
研究＆開発段階	Approved

NF-κB 製品リスト

属性
Cell (2)
製品ライブラリ
オンライン (2)
種
Human (2)
タグ
- (2)
マーカー
- (2)

製品番号	種	発現システム	製品説明	タンパク質の構造	純度	特性
CHEK-ATF048	Human	HEK293	NF-κB (Luc) HEK293 Reporter Cell
SCJUR-STF113	Human	Jurkat	NF-κB (Luc) Jurkat Reporter Cell

総数量2

NF-κB分子の別称

NF-κB, nuclear factor kappa-B

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
NF-kappa-B decoy oligonucleotide	MP-40; MP-41; MP-42; AMS-001; SI-3104; AMG-0101; AMG-0102; AMG-0103; S-414114	Phase 3 Clinical	Anges Mg, Osaka University	Dermatitis, Atopic; Intervertebral Disc Degeneration	詳細
RGN-259	RGN-457; RGN-352; RGN-259; RGN-137; Tβ4; TB4; GBT-101; GBT-201; Thymosin beta 4-16-38; TB4 16-38; Thymosin beta4; Thymosin B4; Fx peptide	Phase 3 Clinical	National Institutes Of Health	Diabetes Mellitus; Dry Eye Syndromes; Epidermolysis Bullosa; Epidermolysis Bullosa Dystrophica; Epidermolysis Bullosa, Junctional; Graft vs Host Disease; Keratitis; Myocardial Infarction; Myocardial Ischemia; Pressure Ulcer; Sjogren's Syndrome; ST Elevation Myocardial Infarction; Varicose Ulcer; Xerophthalmia	詳細
Dazdotuftide	TRS-01	Phase 3 Clinical	Tarsius Pharma	Glaucoma; Ocular inflammation; Uveitis; Uveitis, Anterior	詳細
Hypochlorous Acid	PR-022; PR-013	Phase 3 Clinical	Realm Therapeutics	Cataract; Conjunctivitis, Allergic; Coronavirus Disease 2019 (COVID-19); Dermatitis, Atopic; Endophthalmitis; Virus Diseases	詳細
ARINA-1	ARINA-1	Phase 3 Clinical	Renovion Inc, University Of North Carolina At Chapel Hill	Bronchiectasis; Bronchiolitis Obliterans; Rejection of lung transplantation	詳細
Bezisterim	HE-3286; NE-3107	Phase 3 Clinical	Harbor Therapeutics Inc	Alzheimer Disease; Arthritis, Rheumatoid; Brain Injuries, Traumatic; Colitis, Ulcerative; Diabetes Mellitus, Type 2; Insulin Resistance; Parkinson Disease; Post-Acute COVID-19 Syndrome	詳細
Dimethylaminomicheliolide Fumarate	ACT-001	Phase 3 Clinical	Tianjin Accendatech Technology Co Ltd	Brain metastases; Breast Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Central Nervous System Neoplasms; Glioblastoma; Glioma; Melanoma; Neuromyelitis Optica; Optic Neuritis; Small Cell Lung Carcinoma; Solid tumours	詳細
Nanocurcumin (Tehran University of Medical Sciences)		Phase 2 Clinical	Tehran University Of Medical Sciences	Neoplasms; Periapical Diseases	詳細
APPA	APPA; AKL-4; AKL-IV; APPA-1	Phase 2 Clinical	AKL Research & Development Ltd	Osteoarthritis	詳細
CKBA	CKBA	Phase 2 Clinical	BCY Pharm Co Ltd	Plaque psoriasis; Rosacea; Vitiligo	詳細
IMR-261	CXA-10; IMR-261; E-10-NO2-18:1	Phase 2 Clinical	Complexa Inc	Acute Kidney Injury; Asthma; Glomerulosclerosis, Focal Segmental; Obesity; Phenylketonurias; Pulmonary Arterial Hypertension	詳細
Manganese butoxyethyl pyridyl porphyrin	BMX-001; MnTnBuOE-2-PyP5+	Phase 2 Clinical	Duke University	Astrocytoma; Brain metastases; Carcinoma, Squamous Cell; Endometrial Neoplasms; Glioblastoma; Glioma; Head and Neck Neoplasms; Ovarian Neoplasms; Rectal Neoplasms	詳細
CBL-0137	CX-137; CBL-0137; CBLC-137; Curaxin-CBL0137	Phase 2 Clinical	Cleveland Biolabs Inc	Central Nervous System Neoplasms; Diffuse Intrinsic Pontine Glioma; Diffuse midline glioma; Glioblastoma; Hematologic Neoplasms; Lymphoma; Neoplasms; Sarcoma; Skin Melanoma; Solid tumours	詳細
Zenuzolac	GIT-27; GIT-027; VGX-1027; GLS-1027	Phase 2 Clinical	Geneone Life Science Inc	Coronavirus Disease 2019 (COVID-19); Pneumonia	詳細
Parthenolide	NSC-157035	Phase 2 Clinical	Ashbury Biologicals	Alzheimer Disease; Cognition Disorders; Cognitive Dysfunction; Lymphoma	詳細
Withaferin A		Phase 2 Clinical	UofL Health	Ovarian Neoplasms	詳細
TML-6	TML-6	Phase 2 Clinical	Merry Life Biomedical Co Ltd	Alzheimer Disease	詳細
Proximod		Phase 2 Clinical	Institue Of Materia Medica Chinese Academy Of Medical Science	Arthritis, Rheumatoid	詳細
YIV-906	PHY-906; KD-018	Phase 2 Clinical	Phytoceutica Inc	Carcinoma, Hepatocellular; Colorectal Neoplasms; Diarrhea; Hepatitis B; Liver Neoplasms; Pancreatic Neoplasms; Rectal Neoplasms	詳細
Ascorbic Acid/Menadione		Phase 2 Clinical	Ic-Medtech Co, Summa Health System	Joint Diseases; Prostatic Neoplasms	詳細
LC-280126	MIT-001; LC-280126; NecroX-7; LC28-0126	Phase 2 Clinical	Lg Chemical Ltd	Hematologic Neoplasms; Lymphoma; Multiple Myeloma; Squamous Cell Carcinoma of Head and Neck; ST Elevation Myocardial Infarction; Stomatitis	詳細
Ginsenoside C-K	IH-901; LCHK-168; KBB-N1	Phase 1 Clinical	Fudan University, Il-Hwa, Rohto, State Pharmaceutical Administration of Shanghai Institute of Pharmaceutical Industry, Zhejiang Hisun Pharmaceutical Co Ltd	Arthritis, Rheumatoid; Multiple Myeloma	詳細
ORYN-1001	ORTD-1; ORYN-1001	Phase 1 Clinical	Oryn Therapeutics Llc	Arthritis, Rheumatoid; Coronavirus Disease 2019 (COVID-19)	詳細
CKD-712	CKD-712	Phase 1 Clinical	Chong Kun Dang Pharmaceutical Corp	Sepsis	詳細
LH-025	LH-025	Phase 1 Clinical	Dr August Wolff	Colitis, Ulcerative	詳細
Xempritolimod	KMRC-011; KMRC011; CNT-101; CNT-102	Phase 1 Clinical	Korea Institute Of Industrial Technology	Acute Radiation Syndrome; Graft vs Host Disease; Neoplasms; Stomatitis	詳細
DEN-181	DEN-181; CurcusomeRA; CurcusomeTMRA	Phase 1 Clinical	Dendright	Arthritis, Rheumatoid	詳細
ILB-202	ILB-202; ILB202	Phase 1 Clinical	Ilias Biologics Inc	Acute Kidney Injury; Intraoperative Complications	詳細
SFA-001	SFA-001; SFA-001N	Phase 1 Clinical	SFA Therapeutics Inc, Temple University	Fibrosis; Metabolic Dysfunction-Associated Steatotic Liver Disease	詳細
Sprayable Hypochlorous Acid (RELIFE)	RLF-TD011	Phase 1 Clinical	Relief Therapeutics Holding Sa	Epidermolysis Bullosa	詳細
Reformulated Cepharanthine (Sairiyo Therapeutics Inc)	PD-001; PD001	Phase 1 Clinical	Sairiyo Therapeutics Inc	Communicable Diseases; Neoplasms	詳細
RHN-002	RHN-002; RHN002	Phase 1 Clinical	RH Nanopharmaceuticals LLC	Anemia, Sickle Cell; Pain, Postoperative	詳細
RHN-001	RHN-001; RHN001	Phase 1 Clinical	RH Nanopharmaceuticals LLC		詳細
Hypochlorous Acid/Acetic Acid	SS0350; SS-0350	Phase 1 Clinical	Softox Solutions As	Leg Ulcer; Varicose Ulcer	詳細
SHetA2		Phase 1 Clinical	The University Of Oklahoma	Solid tumours	詳細
TLZ-16-CL	TLZ-16-CL	Phase 1 Clinical	Beijing Taizhou Lize Pharmaceutical Technology Co Ltd	Cocaine-Related Disorders; Substance Withdrawal Syndrome	詳細
Misetionamide	GP-2250	Phase 1 Clinical	Geistlich Pharma	Pancreatic Neoplasms	詳細
Anatabine citrate	RCP-006	Clinical	Rock Creek, Roskamp Institute	Alzheimer Disease; Inflammation; Smoking Cessation; Thyroiditis, Autoimmune; Tobacco Use Disorder	詳細
Tarenflurbil spraygel (MIKA Pharma)		Clinical	Galen Ltd, Mika Pharma Gmbh	Arthritis, Rheumatoid; Dermatitis, Atopic; Inflammation; Pain; Skin Diseases	詳細

市販薬剤に関する情報

英語名	研究コード	研究開発ステージ	会社	オリジナル製品名	最初に承認をした国	最初の適応症	最初に承認を受けた会社	承認された日付	適応症	臨床試験
Glucosamine Hydrochloride		Approved		Dona, Xicil, Dolenio, Dona 200-S, Viartril-S	Mainland China	Osteoarthritis	Bright Future Pharmaceutical Laboratories Ltd	2004-03-17	Chronic Periodontitis; Insulin Resistance; Obesity; Osteoarthritis	詳細
Charcoal	AST-120; MP-146	Approved	Kureha Co	Kremezin, Zysa, Kremezin Fine Granules	Japan	Kidney Failure, Chronic	Mitsubishi Tanabe Pharma	1991-10-04	Asthma; Gastroesophageal Reflux; Hepatic Encephalopathy; Inflammatory Bowel Diseases; Intestinal Fistula; Irritable Bowel Syndrome; Kidney Failure, Chronic; Pouchitis; Renal Insufficiency, Chronic	詳細
Mepacrine hydrochloride	CBL-0102; CBLC-102; Curaxin CBLC-102	Approved	Bayer AG	Atebrin, Maladin, Atabrine, Tenicridine		Lupus Erythematosus, Systemic; Giardiasis; Leishmaniasis; Malaria	Bayer AG	1932-01-01	Carcinoma, Renal Cell; Creutzfeldt-Jakob Syndrome; Giardiasis; Leishmaniasis; Lupus Erythematosus, Systemic; Malaria; Prostatic Neoplasms	詳細
Anapsos	EQA-00	Approved	Asac Pharmaceutical International	Psoriacen		Psoriasis; Dermatitis, Atopic	Asac Pharmaceutical International	1972-01-01	Dermatitis, Atopic; Psoriasis	詳細
Metaxalone (Primus Pharmaceuticals)		Approved	Primus Pharmaceuticals Inc		United States	Muscle Spasticity	Primus Pharmaceuticals Inc	2015-06-01	Muscle Spasticity	詳細
Acetylaconitine		Approved			Mainland China	Pain	Shaanxi Xingbang Pharmacevtical Co Ltd	1985-01-01	Pain	詳細
Andrographolide/Sodium Hydrogen Sulfite		Approved							Bacterial Infections	詳細
Glucosamine Hydrochloride/Chondroitin sulfate		Approved								詳細
Glucosamine Hydrochloride/Indomethacin		Approved			Mainland China	Spondylitis, Ankylosing; Spondylosis; Periarthritis; Arthritis, Rheumatoid; Arthritis	null	1995-01-01	Arthritis; Arthritis, Rheumatoid; Periarthritis; Spondylitis, Ankylosing; Spondylosis	詳細
Glucosamine Hydrochloride/Dermatan sulfate		Approved								詳細
Iguratimod	T-614	Approved	Jiangsu Simcere Pharmaceutical Co Ltd	艾得辛, Colvet, Iremod, Kolbet, Careram	Mainland China	Arthritis, Rheumatoid	Hainan Simcere Pharmaceutical Co Ltd	2011-08-15	Arthritis, Rheumatoid; Graft vs Host Disease; Sjogren's Syndrome	詳細
Anvirzel		Approved	Nerium Biotechnology Inc, Ozelle Pharmaceuticals Inc	Anvirzel					Neoplasms	詳細