Recombinant Monoclonal Anti-Claudin-18.2 Antibody, Mouse (3B10)

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$170.00
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$570.00
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Background

Recombinant Monoclonal Anti-Claudin-18.2 Antibody, Mouse (3B10) is a Claudin-18.2 primary antibody for IHC application. The Claudin-18.2 (CLDN 18.2) protein, an isoform of Claudin 18, a member of the tight junction protein family, is a highly selective biomarker with limited expression in normal tissues and often abnormal expression during the occurrence and development of various primary malignant tumors, such as gastric cancer/gastroesophageal junction (GC/GEJ) cancer, breast cancer, colon cancer, liver cancer, head and neck cancer, bronchial cancer and non-small-cell lung cancer. Claudin-18.2 participates in the proliferation, differentiation and migration of tumor cells. Recent studies have identified Claudin-18.2 expression as a potential specific marker for the diagnosis and treatment of these tumors.

Product Specifications
Host Species
Mouse
Isotype
Mouse IgG1, Mouse Kappa
Clone
3B10
Application
IHC-P
Dilution Ratio
1: 500 - 1: 2000
Form
Liquid
Clonality
Monoclonal
Reactivity
Human
Synonyms
CLDN 18.2
Concentration
0.6~0.9 mg/ml
Specificity
React with Claudin 18.2 protein on the membrane of target cell/tissue; No cross reactivity with Claudin 18.1
Purification Tech
Protein G
Preservation
PBS, 10% Trehalose (pH7.4)
Experiment Protocol
Storage

Shipped at 4°C, Blue Ice. Store at +4°C for 14 days. Store at -20°C for long term.
Avoid freeze / thaw cycle. Upon delivery aliquot.