Monoclonal Anti-VZV gH & gL Antibody, Human IgG1 (4F12)

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GHL-MY2111-100ug
$400.00
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GHL-MY2111-1mg
$2,655.00
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Source

Chimeric Monoclonal Anti-VZV gH & gL Antibody, Human IgG1 (4F12) is recombinantly expressed in HEK293. It consists of mouse variable regions genetically fused to human IgG1 constant domains.

Antibody Type

Recombinant Monoclonal

Clone

4F12

Isotype

Human IgG1, Kappa

Host Species

Mouse

Reactivity

Varicella zoster virus (strain Oka vaccine)

Immunogen

Recombinant Varicella zoster virus (strain Oka vaccine) gH&gL Protein is expressed from human 293 cells

Specificity

Specifically recognizes Varicella zoster virus (strain Oka vaccine) Protein.

Application
Application
Recommended Use / Performance
ELISA
0.2-2 μg/mL
Purification

Protein A purified.

Aggregation

Less than 10%, as determined by SEC-MALS.

Concentration

Please refer to the Certificate of Analysis (CoA).

Form

Lyophilized

Formulation

Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

Please contact us for customized product forms or formulations.

Reconstitution

Please refer to the Certificate of Analysis (CoA) for specific instructions.

Shipping

Lyophilized product is shipped at ambient temperature.

Storage

For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.
Notices

Product Specific Notices: For research use only.

Background

Varicella-zoster virus (VZV) is the alphaherpesvirus that causes chicken pox (varicella) and shingles (zoster). As for all herpesviruses, VZV relies on a fusion complex comprised of three core glycoproteins, gB, gH and gL, required for entry of virions into host cells. VZV ORFs 37 and 60 encode gH (841aa; 118 kDa) and gL (160aa; 20 kDa), respectively, which are N- and O-linked glycosylated and form a heterodimer that is necessary for the activation of gB.