Product Details
Background
Recombinant Monoclonal Anti-MSH2 Antibody, Rabbit (3D2) is a MSH2 primary antibody for IHC application. MSH2 leads mismatch repair (MMR), which is a DNA repair pathway that corrects mispaired based in DNA molecules and restore the correct nucleotide sequence. MSH2 is over-expressed in a variety of tumors in the colon, stomach, breast, pancreas, and lung.
Product Specifications
Host SpeciesRabbitIsotypeRabbit IgG, Rabbit KappaClone3D2ApplicationIHC-PDilution Ratio1: 200 - 1: 1000FormLiquidClonalityMonoclonalReactivityHumanSynonymsMSH2Concentration0.9~1.1 mg/mlSpecificityReact with MSH2 protein on the intracellular area of target cellsPurification TechProtein APreservationPBS, BSA, GlycerolExperiment Protocol
Storage
Shipped at 4°C, Blue Ice. Store at +4°C for short term (1-2 weeks). Store at -20°C for long term.
Avoid freeze / thaw cycle. Upon delivery aliquot. The shelf life is 30 days from the date of opening.ACRO Quality Management System
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Performance Data
Sample Staining Data

Immunohistochemical analysis of paraffin embedded human breast cancer tissue labelled with HGS-S314 at 1/500 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with LEICA BOND IHC staining protocol.
Immunohistochemical analysis of paraffin embedded human lung adenocarcinama tissue labelled with HGS-S314 at 1/500 dilution.
Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with LEICA BOND IHC staining protocol.
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