Anti-SARS-CoV-2 Nucleocapsid Antibody, Mouse IgG1 (AS47) (Trehalose free)

製品番号/仕様
価格
Availability
数量
NUN-S47-100ug
$450.00
NUN-S47-1mg
$3,255.00
NUN-S47-1.5mg
$4,440.00
NUN-S47-10mg
$23,690.00
NUN-S47-100mg
$189,520.00
NUN-S47
製品金額 :
$ 0
推奨新製品 Request Quote
Contact Us
Contact Us
製品金額:
$ 0
  • 製品詳細
  • データ表示
  • Reviews & Citations
  • Important Statement
  • Resources
  • Source

    Anti-SARS-CoV-2 Nucleocapsid Antibody, Mouse IgG1 (AS47) (NUN-S47) was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified recombinant SARS-CoV-2 Nucleocapsid protein. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. ELISA test validated that this antibody can bind multiple N protein variants (Cat. No. NUN-C52H8) with similar affinity as compared to the wild type N protein (Cat. No. NUN-C5227).

  • Clone

    AS47

  • Species

    Mouse

  • Isotype

    Mouse IgG1 | Mouse Kappa

  • Conjugate

    Unconjugated

  • Reactivity

    Virus

  • Specificity

    This product is a specific antibody against SARS-CoV-2 Nucleocapsid protein. No cross-reactivity is detected with nucleocapsid protein of other coronaviruses, including SARS-CoV, MERS-CoV, HCoV-229E, HCoV-NL63, HCoV-OC43 and HCoV-HKU1.

  • Application

    Application
    Recommended Usage
    ELISA
    0.1-10 ng/mL
  • Purity

    95% as determined by SDS-PAGE.

  • Purification

    Protein A purified / Protein G purified

  • Formulation

    Supplied as 0.2 μm filtered solution in PBS, pH7.4 .

    Contact us for customized product form or formulation.

  • Shipping

    This product is supplied and shipped with blue ice, please inquire the shipping cost.

  • Storage

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. For long term storage, the product is stable for up to 12 months at -70°C from date of receipt;
    2. For short term storage, the product is stable for up to 3 months at 2-8°C from date of receipt.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

バックグランド

Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.