Monoclonal Anti-Rabies virus (strain CVS-11) Nucleoprotein Antibody, Mouse IgG2b (2A12)

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数量
NUN-MY2302-100ug
$399.00
In Stock - Delivery in 2-3 business days
NUN-MY2302-1mg (500ug X 2)
$2625.00
In Stock - Delivery in 2 weeks
総アイテム数 製品金額$ 0

製品詳細

  • Source

    Chimeric Monoclonal Anti-Rabies virus (strain CVS-11) Nucleoprotein Antibody, Mouse IgG2b (2A12) is recombinantly expressed in HEK293. It consists of mouse variable regions genetically fused to mouse IgG2b constant domains.

  • Antibody Type

    Recombinant Monoclonal

  • Clone

    2A12

  • Isotype

    Mouse IgG2b, Kappa

  • Host Species

    Mouse

  • Reactivity

    Virus

  • Immunogen

    Recombinant Rabies virus (strain CVS-11) Nucleoprotein is expressed from Baculovirus-Insect cells

  • Specificity

    Specifically recognizes Rabies virus (strain CVS-11) Nucleoprotein.

  • Application

    Application
    Recommended Use / Performance
    ELISA
    0.2-2 μg/mL
  • Purification

    Protein A purified.

  • Aggregation

    Less than 10%, as determined by SEC-MALS.

  • Concentration

    Please refer to the Certificate of Analysis (CoA).

  • Form

    Lyophilized

  • Formulation

    Lyophilized from a 0.22 μm-filtered solution in PBS (pH 7.4), with trehalose as protectant.

    Please contact us for customized product forms or formulations.

  • Reconstitution

    Please refer to the Certificate of Analysis (CoA) for specific instructions.

  • Shipping

    Lyophilized product is shipped at ambient temperature.

  • Storage

    For long term storage, the product should be stored in a lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • Notices

    Product Specific Notices: For research use only.

  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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データ表示

  • Bioactivity-ELISA

     Nucleoprotein/NP (RABV) ELISA

    Immobilized Rabies virus (strain ERA) Nucleoprotein, His Tag (Cat. No. NUN-R55H3) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Rabies virus (strain CVS-11) Nucleoprotein Antibody, Mouse IgG2b (2A12) (Cat. No. NUN-MY2302) with a linear range of 0.02-1 ng/mL (QC tested).

    Protocol

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よくある質問

  • product

    Can lyophilized proteins remain stable during room-temperature shipping or temporary room-temperature exposure?

    In general, lyophilized proteins remain stable during room-temperature shipping or temporary exposure to room-temperature conditions.


    Many ACROBiosystems recombinant proteins are supplied in lyophilized (freeze-dried) form. The lyophilization process effectively removes moisture from the product, helping reduce degradation-related reactions and improve protein stability during transportation and storage.


    To evaluate the stability of lyophilized proteins under normal temperature conditions, ACROBiosystems conducted a stability study on 11 representative lyophilized protein products at 37°C. The study demonstrated that these proteins maintained good quality stability after storage at 37°C for approximately 20 days. Based on these validation results, temporary room-temperature exposure during shipping or handling is generally not expected to have a significant impact on product quality or downstream application performance.


    To ensure optimal long-term stability, products should be stored according to the storage conditions specified in the product Certificate of Analysis (COA) upon receipt.


    Supporting Document


バックグランド

The ​​Anti-Rabies Virus Nucleoprotein Antibody​​ targets the ​​nucleoprotein (N protein)​​ of rabies virus (RABV), a structural protein essential for viral replication. The N protein encapsidates the viral RNA genome, forming the ribonucleoprotein (RNP) complex that serves as the template for transcription and replication by the viral polymerase. This antibody is typically generated using recombinant N protein as an immunogen and purified via affinity chromatography. It is widely used for ​​detecting rabies virus in diagnostic assays​​ such as immunofluorescence, Western blotting, and ELISA, aiding in the identification of viral inclusions like Negri bodies in infected neural tissues. Its specificity supports research on viral pathogenesis and host immune responses.

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