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Product Details
- ProductSizeAmountActiveMax® Human DLL3 μBeads, premium grade (for cells)2.5 mg2.5×10⁷ beadsActiveMax® Human DLL3 μBeads, premium grade (for cells)10 mg (2.5 mg×4)1.0×10⁸ beads
Product Description
ActiveMax® Human DLL3 μBeads, premium grade (for cells) are uniform, superparamagnetic beads of 5.5 µm in diameter immobilized with Human DLL3 Protein, expressed from human 293 cells (HEK293) and contains AA Ala 27 - Leu 492 (Accession # Q9NYJ7-1).
ActiveMax® Human DLL3 μBeads, premium grade (for cells) are produced under sterile manufacturing conditions (ISO 5) , and no animal- or human-derived components are used throughout the production process. It is produced under our rigorous quality control system that includes a comprehensive set of tests including sterility and endotoxin tests.Application
ActiveMax® Human DLL3 μBeads, premium grade (for cells) are designed to stimulate in vitro DLL3-specific CAR-T cells or UCAR-T cells, similar to the tumor cell lines that express human DLL3 antigen. It can be used as follows:
Evaluating the characteristics of CAR-T cells or UCAR-T cells.
In vitro expansion of DLL3-specific CAR-T cells or UCAR-T cells.
In vitro enrichment of DLL3-specific CAR-T cells or UCAR-T cells.Reconstitution
See Certificate of Analysis (CoA) for detailed instruction.
Storage
This product is stable in storage under the following conditions: -20˚C for 12 months in lyophilized state. -70°C for 3 months under sterile conditions after reconstitution.
Please protect from light and avoid repeated freeze-thaw cycles. Immediate use after reconstitution is highly recommended.
Sterility
Negative
Mycoplasma
Negative
Important Note
This product is for research use only and not intended for therapeutic or in vivo diagnostic use.
Formulation
Lyophilized in PBS with 0.1% HSA，pH 7.4. Trehalose is added as protectant before lyophilization.
ACRO Quality Management System
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Performance Data
FACS Data
Assay of human DLL3 protein on the μBeads surface by Flow cytometry. The human DLL3 protein conjugated on the μBeads (Cat. No. MBS-C018) surface were fluorescently stained using anti-human DLL3 antibody and PE anti-human IgG Fc Recombinant Antibody, and then analyzed by flow cytometry.
Protocol
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FAQ
- product
Can lyophilized proteins remain stable during room-temperature shipping or temporary room-temperature exposure?
In general, lyophilized proteins remain stable during room-temperature shipping or temporary exposure to room-temperature conditions.
Many ACROBiosystems recombinant proteins are supplied in lyophilized (freeze-dried) form. The lyophilization process effectively removes moisture from the product, helping reduce degradation-related reactions and improve protein stability during transportation and storage.
To evaluate the stability of lyophilized proteins under normal temperature conditions, ACROBiosystems conducted a stability study on 11 representative lyophilized protein products at 37°C. The study demonstrated that these proteins maintained good quality stability after storage at 37°C for approximately 20 days. Based on these validation results, temporary room-temperature exposure during shipping or handling is generally not expected to have a significant impact on product quality or downstream application performance.
To ensure optimal long-term stability, products should be stored according to the storage conditions specified in the product Certificate of Analysis (COA) upon receipt.
Supporting Document
Recent Advances
Drug Development Progress- English Name：
Delta-like protein 3
- Category：
- Approved Drugs：
1 Details
- Drugs in Clinical Trials：
28 Details
- Highest Development Stage：
Approved
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