Mogengel Matrix Organoid Culture (Acro Certified)

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製品番号/仕様
価格
数量
AC-M082755-5ml
$265.00
AC-M082755-10ml
$415.00
総アイテム数 製品金額$ 0

製品詳細

  • Product Show

    Mogengel PRODUCT SHOW
  • Key Benefits

    1. Long - term Culture for Organoid Validated - Strict Quality Control Assays for every produced lot.
    2. Lot-to-lot Consistency - Strict manufacturing controls and management systems.
    3. Stable, Long-term Supply - Large-scale manufacturing capacity and ACRO’s global supply chain.
    4. Cost Effective - Bulk pricing available to meet your research needs.

  • Intended Use

    Mogengel Matrix Organoid Culture is intended to be used for robust, reproducible organoid culturing. For organoids that are harder to culture with other types of culturing media, try this series of Mogengel Matrix to ensure effectiveness and reproducibility of organoid studies. This includes studies on mouse intestinal organoids, lung organoids, human brain organoids, and so on.

  • Product Description

    1. Basement membranes are comprised of continuous sheets of a specialized extracellular matrix. It acts an interface between various types of cells, including muscle, neuronal, epithelial, or endothelial cells, along with adjacent stroma. Basement membranes are an essential part in the organization of tissues forming the scaffolding and support for cellular growth and cell layers. They also affect a variety of cellular mechanisms such as adhesion, migration, proliferation, and differentiation. Basement membranes are selectively degraded and regenerated during development and wound healing, forming the base scaffold for tissue reconstruction. Basement membranes also act as a major barrier to invasion by metastatic tumor cells.
    2. Mogengel Matrix Organoid Culture is a soluble form of basement membrane that is purified from gene-edited mouse tumor cells grown in LDEV-free mouse populations. Reconstitution into the original basement membrane form occurs at 37℃ and is mainly comprised of laminin, collagen IV, entactin, and heparin sulfate proteoglycan.
  • Specification

    Protein Concentration
    Within 8 to 12 mg/mL, tested by BCA assay.
    Endotoxin Level
    < 4.5 EU/mL, tested by LAL assay.
    Organoid Culture
    Mouse intestinal organoids, mouse liver ductal organoids and mouse airway organoids could grow well under the Mogengel Matrix.
    *Evaluated Mogengel Matrix: Medium Ratio = 7:3 (v/v).
    Angiogenesis
    Blood vessel formation is observed, tested by HUVEC angiogenesis assay.
    *Evaluated Mogengel Matrix: Medium Ratio = 1:0 (original formulation), 2:1, 1:1 (v/v).
    Sterility
    No growth observed after 14 days. Testing for the detection of bacteria, fungi, and mycoplasma through cell culture.
    Viral Testing
    Tested negative by ELISA, bacterial culture and microscope observation for a total of 19 bacterial and virus strains, and additional murine infectious agents including LDEV.
    Stability
    Product is stable for at least two years from date of manufacture when stored at ≤ -20℃. See lot specific Certificate of Analysis for expiration date.
    Shipping Conditions
    The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended on the product label.
    Storage
    Store at -20℃. Avoid multiple freeze-thaws. Do not store in frost-free freezer. KEEP FROZEN.

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データ表示

  • Bioactivity-Tumor Organoid Culture

     Mogengel TUMOR ORGANOID CULTURE

    Human tumor organoids (colorectal cancer organoids, gastric cancer organoids) can grow well in greater than 70% Mogengel (Cat. No. AC-M082755).

  • Bioactivity- Long-term Culture For Mouse Organoid

     Mogengel LONG-TERM CULTURE FOR MOUSE ORGANOID

    Mogengel (Cat. No. AC-M082755) can maintain the stability of organoid passage. Long-term expansion of mouse small intestinal organoids for more than 7 passages with typical organoid budding morphology and marker expression.

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重要な声明

  • Acro Certify Disclaimer

    This product is one of ACROBiosystems' Certify products. ACROBiosystems and our Certify partners have established a close partnership that includes an in-depth review of quality management and quality audits this product. Products from our Certify partners have been qualified by ACROBiosystems to be included under Acro Certify. ACROBiosystems may provide Product information, including technical information, specifications, recommendations, literature, and other material (collectively, "Product Information") for customer's convenience. The accuracy and completeness of Product Information is not guaranteed and is subject to change without notice. ACROBiosystems is not responsible for the intellectual property or impact to intellectual property for products sold under Acro Certify.

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