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Human BTN2A1 / Butyrophilin Protein, His Tag, low endotoxin (MALS verified)

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BT1-H52H6-100ug
$395.00
In Stock - Delivery in 1-2 business days
BT1-H52H6-1mg (500ug X 2)
$2,615.00
In Stock - Delivery in 2 weeks
BT1-H52H6
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Synonyms

BK14H9.1, BT2.1, BTF1, BTF1BT2.1butyrophilin BTF1, BTN2A1, butyrophilin subfamily 2 member A1, butyrophilin, subfamily 2, member A1, DJ3E1.1, FLJ36567

Source

Human BTN2A1 Protein, His Tag (BT1-H52H6) is expressed from human 293 cells (HEK293). It contains AA Gln 29 - Ala 248 (Accession # Q7KYR7-2).

Predicted N-terminus: Gln 29

Molecular Characterization

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 26.4 kDa. The protein migrates as 38-45 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 0.01 EU per μg by the LAL method / rFC method.

Purity

>95% as determined by SDS-PAGE.

>95% as determined by SEC-MALS.

Formulation

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System

バックグランド

Duplication events have led to three paralogues of BTN2A in primates: BTN2A1, BTN2A2, and BTN2A3. In humans, only BTN2A1 has been functionally characterised; it has been detected on epithelial cells and leukocytes, and identified as a novel ligand of dendritic cell-specific ICAM-3 grabbing nonintegrin (DCSIGN), a C-type lectin receptor that acts as an internalization receptor for HIV-1, HCV, and other pathogens. BTN2A2 mR has been shown to be expressed in circulating human immune cells.