Human CEACAM-5 Protein, Fc Tag (HPLC verified)

Customer Reviews
Cat. No. / Size
Price
Qty
CE5-H5253-100ug
$310.00
CE5-H5253-1mg (250ug X 4)
$2245.00
ETA of in-stock products:2 business days

Product Details

  • Synonyms

    CEACAM-5, CD66e, CEA, Meconium antigen 100

  • Source

    Human CEACAM-5, Fc Tag (CE5-H5253) is expressed from human 293 cells (HEK293). It contains AA Lys 35 - Ala 685 (Accession # P06731-1).

    Predicted N-terminus: Lys 35

    Request for sequence
  • Molecular Characterization

    CEACAM-5 Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 97.8 kDa. The protein migrates as 150-180 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SDS-PAGE.

    >95% as determined by SEC-HPLC.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

Customers Also Viewed

Performance Data

  • SDS-PAGE

    CEACAM-5 SDS-PAGE

    Human CEACAM-5, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-HPLC

    CEACAM-5 SEC-HPLC

    The purity of Human CEACAM-5, Fc Tag (Cat. No. CE5-H5253) was greater than 95% as determined by SEC-HPLC.

  • Bioactivity-ELISA

     CEACAM-5 ELISA

    Immobilized Human CEACAM-5, Fc Tag (Cat. No. CE5-H5253) at 1 μg/mL (100 μL/well) can bind Labetuzumab with a linear range of 1-10 ng/mL (QC tested).

    Protocol

Customer Reviews
Writing Reviews

Background

Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) is also Carcinoembryonic antigen (CEA), Meconium antigen 100, CD antigen CD66e, CEACAM5 belongs to the immunoglobulin superfamily and CEA family. CEACAM5 contains seven Ig-like (immunoglobulin-like) domains. CEACAM5 is homodimer protein which binding of E.coli Dr adhesins leads to dissociation of the homodimer. CEACAM5 is cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. CEACAM5 is receptor for E.coli Dr adhesins.

Recent Advances

 
Drug Development Progress
  • English Name:

    Carcinoembryonic antigen related cell adhesion molecule 5

  • Category:

  • Approved Drugs:

    0 Details

  • Drugs in Clinical Trials:

    18 Details

  • Highest Development Stage:

    Phase 3 Clinical

Contact Us
Drug Candidate Licensing
More
  • Basic Product Information
  • Product Details
  • Customers Also Viewed
  • Performance Data
  • Customer Reviews
  • Background
Contact Us

お問い合わせ
グローバル:+1 800-810-0816(Toll Free)

メールアドレス
order.jp@acrobiosystems.com

アクロバイオシステムズ株式会社
〒101-0051
東京都千代田区神田神保町1-32-8