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This product is in development. If you are interested in this product, please contact us directly. We will accelerate our R&D process according to your needs and reserve the product for you.
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CLC-H52H3-100ug
$350.00
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CLC-H52H3-1mg
$2,310.00
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CLC-H52H3
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  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources

分子别名（Synonym）

DLEC,CLEC4C,BDCA-2,CD303,CLECSF11,CLECSF7, HECL

表达区间及表达系统（Source）

Human CLEC4C, His Tag (CLC-H52H3) is expressed from human 293 cells (HEK293). It contains AA Asn 45 - Ile 213 (Accession # Q8WTT0-1).

Predicted N-terminus: His

蛋白结构（Molecular Characterization）

Online-Res(Asn 45 - Ile 213) Q8WTT0-1

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 21.8 kDa.

内毒素（Endotoxin）

制剂（Formulation）

Please contact us for detailed information.

Contact us for customized product form or formulation.

重构方法（Reconstitution）

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

存储（Storage）

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

  1. -20°C to -70°C for 12 months in lyophilized state;
  2. -70°C for 3 months under sterile conditions after reconstitution.

Background

CLEC4C (C-type lectin domain family 4 member C), also known as BDCA2, CLECSF11, CLECSF7, DLEC and CD303. Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cell. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.