Human Coagulation factor IX / F9 Protein, His Tag, low endotoxin (Pro-form, MALS verified)

製品番号/仕様
価格
Availability
数量
FIX-H52H3-20ug
$410.00
In Stock - Delivery in 2 weeks
FIX-H52H3-100ug
$1,545.00
In Stock - Delivery in 1-2 business days
FIX-H52H3-500ug
$5,770.00
In Stock - Delivery in 1-2 business days
FIX-H52H3
製品金額 :
$ 0
推奨新製品 Request Quote
Contact Us
Contact Us
製品金額:
$ 0
  • 製品詳細
  • データ表示
  • Reviews & Citations
  • Important Statement
  • Resources
Synonyms

Coagulation factor Ix, PTC, F9, THPH8, FIX, Plasma Thromboplastic Component, factor Ix

Source

Human Coagulation factor IX Protein, His Tag (FIX-H52H3) is expressed from human 293 cells (HEK293). It contains AA Thr 29 - Thr 461 (Accession # P00740-1).

Predicted N-terminus: Thr 29

Molecular Characterization

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 50.6 kDa. The protein migrates as 60-68 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 0.01 EU per μg by the LAL method / rFC method.

Purity

>90% as determined by SDS-PAGE.

>90% as determined by SEC-MALS.

Formulation

Lyophilized from 0.22 μm filtered solution in 50 mM Tris,150 mM NaCl,pH8.0 with trehalose as protectant.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.

バックグランド

Coagulation Factor IX is also known as F9, FIX, and P19. Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca2+ ions, phospholipids, and factor VIIIa,and plays an important role in the intrinsic blood coagulation cascade. As a key component of the clotting cascade, Factor IX helps form stable blood clots and prevents excessive bleeding.