製品詳細
Synonyms
CD217, CDw217, IL-17RA, IL17R, CANDF5, hIL-17R
Source
Human IL-17 RA Protein, Fc Tag (ILA-H525f) is expressed from human 293 cells (HEK293). It contains AA Leu 33 - Trp 320 (Accession # Q96F46-1).
Predicted N-terminus: Leu 33
Molecular Characterization
This protein carries a human IgG1 Fc tag at the C-terminus.
The protein has a calculated MW of 59.9 kDa. The protein migrates as 75-95 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 1.0 EU per μg by the LAL method / rFC method.
Purity
>95% as determined by SDS-PAGE.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System
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データ表示
SDS-PAGE

Human IL-17 RA Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).
SEC-MALS

The purity of Human IL-17 RA Protein, Fc Tag (Cat. No. ILA-H525f) is more than 85% and the molecular weight of this protein is around 155-185 kDa verified by SEC-MALS.
Report
Bioactivity-ELISA

Immobilized Human IL-17F, His Tag (Cat. No. ILF-H5244) at 2 μg/mL (100 μL/well) can bind Human IL-17 RA Protein, Fc Tag (Cat. No. ILA-H525f) with a linear range of 4-63 ng/mL (QC tested).
Protocol
Immobilized Human IL-17 RA Protein, Fc Tag (Cat. No. ILA-H525f) at 2 μg/mL (100 μL/well) can bind Biotinylated Human IL17A, His,Avitag (Cat. No. ILA-H82Q1) with a linear range of 0.1-2 ng/mL (Routinely tested).
Protocol
Bioactivity-SPR

Human IL-17 RA Protein, Fc Tag (Cat. No. ILA-H525f) captured on Protein A Chip can bind Human IL-17A Protein, His Tag (Cat. No. ILA-H5243) with an affinity constant of 0.360 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).
Protocol
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最新の進展
- 英語名:
Interleukin-17 receptor A
- カテゴリ:
- 市販の医薬品数:
1 詳細
- 治験医薬品数:
2 詳細
- 最新の開発ステージ:
Approved
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