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製品詳細
Synonyms
IL-22, IL-TIF, ZCYTO18
Source
Mouse IL-22 Protein, His Tag (IL2-M52H6) is expressed from human 293 cells (HEK293). It contains AA Leu 34 - Val 179 (Accession # Q9JJY9).
Predicted N-terminus: Leu 34
Request for sequenceMolecular Characterization
Other Tags and Version Biotin & Other Labeled Version
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 18.5 kDa. The protein migrates as 25-35 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
Less than 1.0 EU per μg by the LAL method / rFC method.
Purity
>95% as determined by SDS-PAGE.
>90% as determined by SEC-HPLC.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
Reconstitution
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
Storage
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System
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データ表示
SDS-PAGE
Mouse IL-22 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).
SEC-HPLC
The purity of Mouse IL-22 Protein, His Tag (Cat. No. IL2-M52H6) was greater than 90% as determined by SEC-HPLC.
Bioactivity-ELISA
Immobilized Mouse IL-22 Protein, His Tag (Cat. No. IL2-M52H6) at 5 μg/mL (100 μL/well) can bind Human IL-22 R alpha 1, Fc Tag with a linear range of 0.01-0.313 μg/mL (Routinely tested).
Protocol
Bioactivity-SPR
Mouse IL-22 R alpha 1 Protein, His Tag (Cat. No. IL1-M52H8) immobilized on CM5 Chip can bind Mouse IL-22 Protein, His Tag (Cat. No. IL2-M52H6) with an affinity constant of 85.1 nM as determined in a SPR assay (Biacore 8K) (QC tested).
Protocol
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最新の進展
医薬品開発の進捗- 英語名：
Interleukin-22
- カテゴリ：
- 市販の医薬品数：
0 詳細
- 治験医薬品数：
3 詳細
- 最新の開発ステージ：
Phase 3 Clinical
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