GMP Human Laminin 511 Protein (Mix & Scale)

GMP Human Laminin 511 Protein (Mix & Scale) is a recombinant human laminin 511 E8 (LN511-E8) protein that provides a defined surface for in vitro feeder-free culture of multiple human pluripotent stem cells (PSCs).
As published by Takamichi Miyazaki et al., the LN511-E8 variant of laminin 511 shows higher efficiency for supporting the adhesion of dissociated cells than did wild-type laminin 511 which makes it a cost-effective choice.
LN511-E8 has been proven to maintain normal growth characteristics and stemness in multiple PSC lines without simultaneous differentiation, which includes ESC, iPSC, MSC, etc. In addition, LN511-E8 has been demonstrated to support PSC growth for > 10 passages without any signs of karyotypic abnormalities and to maintain the ability of PSCs to differentiate into all three germ line lineages.
This product is designed and developed utilizing our proprietary AI technology, which is protected by patent rights. We retain full commercial rights to this product.
Importantly, our innovative laminin 511 protein (Mix & Scale) could meanwhile support pre-coating method and suspension method (directly mixing the protein with cell suspensions without coating plates).

• Scalable Manufacturing Designed: No coating steps required, simplifies operation and enables seamless automation in large-scale GMP production.
• Significant Cost Efficiency​: Achieves substantial cost savings compared to traditional coating methods.
• Reliable Stemness Maintenance​: Supports stable hPSC expansion over multiple passages without spontaneous differentiation.
• Comprehensive Safety Assurance: ATCC-compliant CHO host cell origin and comprehensive testing (52 items), full MCB testing coverage, validated dual viral clearance.

• Quality Assurance: Global QMS with comprehensive and stringent QC release criteria.
• End-to-End GMP Compliance: Full manufacturing and QC under a cGMP system.
• Comprehensive Control of Adventitious Agents: Stringent biosafety from cell banks to final release.
• Comprehensive Regulatory Support: Includes RSF and DMF to meet global requirements.
• Resilient Supply Chain: Intelligent modular facilities ensure a stable global supply.
• Professional Support: Extensive manufacturing and application expertise to accelerate development.

CHO

Supplied as 0.2 μm filtered solution in PBS, pH7.4 with protectants.

Contact us for customized product form or formulation.

2R (13 mm neck finish)

This product is supplied and shipped with dry ice, please inquire the shipping cost.

For long term storage, the product should be stored at liquid state at -20℃ or below.

Please avoid repeated freeze-thaw cycles.

• 2-8°C for 6 months under sterile conditions;
• -20°C or below for 3 years.