Human MRGPRX2 Full Length Protein, Flag Tag (Nanodisc-pro)

AIDD‑Ready
Related Products: Cell line CHEK-ATP214
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Availability
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MR2-H52D3-20ug
$750.00
In Stock - Delivery in 2-3 weeks
MR2-H52D3-100ug
$1,500.00
In Stock - Delivery in 2-3 weeks
MR2-H52D3-500ug
$4,800.00
In Stock - Delivery in 1-2 business days
MR2-H52D3
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Application
  • Cell based assay (FACS or functional assay)
  • Affinity testing (SPR / BLI)
  • Screening (ELISA)
Synonyms

MRGPRX2

Source

Nanodisc-pro Human MRGPRX2 Full Length Protein, Flag Tag (MR2-H52D3) is expressed from human 293 cells (HEK293). It contains AA Asp 2 - Val 330 (Accession # Q96LB1).

Predicted N-terminus: Asp

Molecular Characterization

This protein carries a flag tag at the N-terminus. The protein has a calculated MW of 53.3 kDa.

*The isotype control of empty/mock nanodisc (Cat. No. APO-H5143) is sold separately and not included in protein, you can follow the link for product information.

Structure

Nanodisc-pro membrane protein is wrapped by a piece of cell membrane and scaffold, the info of scaffold can be found in above red text "isotope type control...".

Synthesis Process

Nanodisc-pro membrane protein extraction is a gentle, non-disruptive process that directly isolates full-length transmembrane proteins together with their surrounding native phospholipids from cellular membranes, without breaking or disturbing the original membrane structure. This preserves the membrane protein's natural conformational landscape and native lipid environment, yielding stable nanodisc that retain cellular phospholipids, with fully preserved biological activity—making them ideal for cell-based assays such as FACS and binding assays in antibody discovery and screening (ELISA), etc.

Purity

>90% as determined by SDS-PAGE.

Formulation

Supplied as 0.2 μm filtered solution in 20 mM HEPES, 150 mM NaCl, pH7.5 with glycerol as protectant.

Contact us for customized product form or formulation.

Shipping and Storage

This product is supplied and shipped on dry ice.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • The product MUST be stored at -70°C or lower upon receipt;
  • -70°C for 3 months under sterile conditions.

バックグランド

The protein belongs to the family of G-protein coupled receptors, that are preferentially activated by adenosine and uridine nucleotides. It is moderately expressed in undifferentiated HL60 cells, and is located on both chromosomes X and Y.