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Influenza A virus (A/Croatia/10136RV/2023) & (A/District of Columbia/27/2023) NA(H3N2) Protein, His Tag

製品番号/仕様
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NEE-V524x-100ug
$360.00
In Stock - Delivery in 1-2 business days
NEE-V524x-1mg
$2,760.00
In Stock - Delivery in 1-2 business days
NEE-V524x
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製品詳細
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  • 製品詳細
  • データ表示
  • Reviews & Citations
  • Important Statement
  • Resources
Synonyms

NA, Neuraminidase

Source

Influenza A virus (Croatia/10136RV) & (Columbia/27) NA(H3N2) Protein, His Tag (NEE-V524x) is expressed from human 293 cells (HEK293). It contains AA Ile 30 - Thr 469 (Accession # EPI3472932 & EPI2990330, GISAID).

Predicted N-terminus: His

Molecular Characterization

This protein carries a polyhistidine tag at the N-terminus.

The protein has a calculated MW of 51.0 kDa. The protein migrates as 60-75 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>90% as determined by SDS-PAGE.

Formulation

Supplied as 0.2 μm filtered solution in 50 mM Tris, 500 mM NaCl, pH7.5 with trehalose as protectant.

Contact us for customized product form or formulation.

Shipping and Storage

This product is supplied and shipped on dry ice.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • The product MUST be stored at -70°C or lower upon receipt;
  • -70°C for 3 months under sterile conditions.
ACRO Quality Management System

バックグランド

Influenza, commonly known as 'the flu', is an infectious disease of birds and mammals caused by RNA viruses of the family Orthomyxoviridae, the influenza viruses. The virus is divided into three main types (Influenzavirus A, Influenzavirus B, and Influenzavirus C), which are distinguished by differences in two major internal proteins (hemagglutinin (HA) and neuraminidase (NA), which are the most important targets for the immune system. Hemagglutinin binds to the sialic acid-containing receptors on the surface of host cells during initial infection and at the end of an infectious cycle which makes it a great target for vaccine studies.