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Hamster PLBD2 / PLBL2 Protein, His Tag

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PL2-H51H3-100ug
$610.00
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PL2-H51H3-1mg (500ug X 2)
$3,960.00
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PL2-H51H3
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Product Details
Performance Data
Reviews & Citations
Resources
  • Product Details
  • Performance Data
  • Reviews & Citations
  • Important Statement
  • Resources
Synonyms

PLBD2

Source

Hamster PLBD2 Protein, His Tag (PL2-H51H3) is expressed from CHO cells. It contains AA Leu 38 - Asp 585 (Accession # G3I6T1-1).

Predicted N-terminus: Leu 38

Molecular Characterization
Other Tags and Version Biotin & Other Labeled Version

This protein carries a polyhistidine tag at the C-terminus.

The protein has a calculated MW of 63.7 kDa. The protein migrates as 43 kDa and 70-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>95% as determined by SDS-PAGE.

Formulation

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.
ACRO Quality Management System

Background

PLBL2 (also annotated as PLBD2, phospholipase B–like 2) is a lysosome-localized, functionally semi-orphan member of the phospholipase B family. Its mature, active form depends on ordered post-translational processing—signal-peptide removal, mannose-6-phosphate–mediated lysosomal targeting, and an autocatalytic cleavage step. In biopharmaceutical production, especially from CHO cells, PLBL2 is classified among high-risk host cell proteins (HCPs): it persists through downstream purification owing to its stability and clearance-resistant properties, creating a potential immunogenicity hazard (anti-HCP/anti-drug antibody risk) that mandates sensitive, specific monitoring.