Human RON / MSPR Protein, His Tag (MALS verified)

Synonyms

CD136 antigen, CD136, CDw136c-met-related tyrosine kinase, EC 2.7.10, EC 2.7.10.1, macrophage stimulating 1 receptor (c-met-related tyrosine kinase), MSP R, MSP receptor, MSPR, MST1R, p185-Ron, Protein-tyrosine kinase 8, PTK8 protein tyrosine kinase 8, PTK8, Ron, RONmacrophage-stimulating protein receptor, RON

Source

Human RON, His Tag (RON-H52H9) is expressed from human 293 cells (HEK293). It contains AA Glu 25 - Leu 571 (Accession # Q04912-1).

Molecular Characterization

Other Tags and Version Biotin & Other Labeled Version

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 60.7 kDa. This protein contains a furin cleavage site, 306-RRRR-309, and will be processed into disulfide-linked alpha chain and partial beta chain, with calculated MW of 30.6 kDa (alpha chain) and 30.1 kDa (partial beta chain), respectively. The protein migrates as 33-35 kDa and 36-43 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>95% as determined by SDS-PAGE.

>90% as determined by SEC-MALS.

Formulation

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:

1. -20°C to -70°C for 12 months in lyophilized state;
2. -70°C for 3 months under sterile conditions after reconstitution.

ACRO Quality Management System

1. QMS(ISO, GMP)
2. Quality Advantages
3. Quality Control Process