Human SUSD6 Protein, Tag Free

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SU6-H5213-100ug
$420.00
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SU6-H5213-1mg (500ug X 2)
$2,720.00
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SU6-H5213
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Synonyms

SUSD6

Source

Human SUSD6 Protein, Tag Free (SU6-H5213) is expressed from human 293 cells (HEK293). It contains AA Ser 40 - Ser 120 (Accession # Q92537).

Molecular Characterization

This protein carries no "tag".

The protein has a calculated MW of 9.8 kDa. The protein migrates as 8 kDa and 12 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Endotoxin

Less than 1.0 EU per μg by the LAL method / rFC method.

Purity

>90% as determined by SDS-PAGE.

Formulation

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

Contact us for customized product form or formulation.

Reconstitution

Please see Certificate of Analysis for specific instructions.

For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

Shipping and Storage

This product is shipped at ambient temperature.

For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Please avoid repeated freeze-thaw cycles.

This product is stable after storage at:
  • -20°C to -70°C for 12 months in lyophilized state;
  • -70°C for 3 months under sterile conditions after reconstitution.

Background

SUSD6 is a Type I transmembrane protein, the extracellular portion of which contains a characteristic Sushi domain (also known as a Complement Control Protein domain). This domain typically mediates protein-protein interactions. Dysregulated expression of SUSD6 is closely associated with the pathogenesis, progression, and prognosis of various cancers. Its core characteristics lie in its ability to promote apoptosis via the DR5 pathway and its dualistic role across different cancer types.