Mouse TPBG / 5T4 Protein, Fc Tag (MALS verified)

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製品番号/仕様
価格
数量
TPG-M5255-100ug
$360.00
TPG-M5255-1mg (500ug X 2)
$2615.00
ETA of in-stock products:2 business days
総アイテム数 製品金額$ 0

製品詳細

  • Synonyms

    TPBG, 5T4, M6P1, 5T4AG, WAIF1, 5T4 oncofetal antigen, Trophoblast glycoprotein, 5T4 oncofetal trophoblast glycoprotein

  • Source

    Mouse TPBG Protein, Fc Tag (TPG-M5255) is expressed from human 293 cells (HEK293). It contains AA Ser 32 - Ser 361 (Accession # Q9Z0L0-1).

    Predicted N-terminus: Ser 32

    Request for sequence
  • Molecular Characterization

    TPBG Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a human IgG1 Fc tag at the C-terminus.

    The protein has a calculated MW of 62.2 kDa. The protein migrates as 80-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

  • Endotoxin

    Less than 1.0 EU per μg by the LAL method / rFC method.

  • Purity

    >90% as determined by SDS-PAGE.

    >90% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Shipping and Storage

    This product is shipped at ambient temperature.

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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データ表示

  • SDS-PAGE

    TPBG SDS-PAGE

    Mouse TPBG Protein, Fc Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90%.

  • SEC-MALS

    TPBG SEC-MALS

    The purity of Mouse TPBG Protein, Fc Tag (Cat. No. TPG-M5255) is more than 90% and the molecular weight of this protein is around 150-180 kDa verified by SEC-MALS.

    Report

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バックグランド

Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues.This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. TPBG is expressed by all types of trophoblasts as early as 9 weeks of development.

最新の進展

 
医薬品開発の進捗
  • 英語名:

    Trophoblast glycoprotein

  • カテゴリ:

  • 市販の医薬品数:

    0 詳細

  • 治験医薬品数:

    16 詳細

  • 最新の開発ステージ:

    Phase 2 Clinical

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