Mouse Transferrin R / CD71 Protein, His Tag (MALS verified)

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製品番号/仕様
価格
数量
TFR-M524b-100ug
$415.00
TFR-M524b-1mg
$2695.00
ETA of in-stock products:2 business days
総アイテム数 製品金額$ 0

製品詳細

  • Synonyms

    CD71, TFRC, TFR, sTfR, TfR1, Trfr, T9, p90

  • Source

    Mouse Transferrin R, His Tag (TFR-M524b) is expressed from human 293 cells (HEK293). It contains AA Cys 89 - Phe 763 (Accession # Q62351-1).

    Predicted N-terminus: His

    Request for sequence
  • Molecular Characterization

    Transferrin R Structure

    Other Tags and Version Biotin & Other Labeled Version

    This protein carries a polyhistidine tag at the N-terminus.

    The protein has a calculated MW of 77.8 kDa. The protein migrates as 80-90 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

    The protein is designed as a dimer.

  • Endotoxin

    Less than 0.1 EU per μg by the LAL method / rFC method.

  • Purity

    >95% as determined by SDS-PAGE.

    >95% as determined by SEC-MALS.

  • Formulation

    Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

    Contact us for customized product form or formulation.

  • Reconstitution

    Please see Certificate of Analysis for specific instructions.

    For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.

  • Storage

    For long term storage, the product should be stored at lyophilized state at -20°C or lower.

    Please avoid repeated freeze-thaw cycles.

    This product is stable after storage at:

    1. -20°C to -70°C for 12 months in lyophilized state;
    2. -70°C for 3 months under sterile conditions after reconstitution.
  • ACRO Quality Management System

    1. QMS(ISO, GMP)
    2. Quality Advantages
    3. Quality Control Process

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データ表示

  • SDS-PAGE

    Transferrin R SDS-PAGE

    Mouse Transferrin R, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 95% (With Star Ribbon Pre-stained Protein Marker).

  • SEC-MALS

    Transferrin R SEC-MALS

    The purity of Mouse Transferrin R, His Tag (Cat. No. TFR-M524b) is more than 95% and the molecular weight of this protein is around 135-165 kDa verified by SEC-MALS.

    Report
  • Bioactivity-ELISA

     Transferrin R ELISA

    Immobilized Mouse Transferrin R, His Tag (Cat. No. TFR-M524b) at 5 μg/mL (100 μL/well) can bind Mouse Transferrin, Mouse IgG2a Fc Tag, low endotoxin (Cat. No. TRN-M525b) with a linear range of 0.4-25 ng/mL (QC tested).

    Protocol

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バックグランド

CD antigen CD71 is also known as Transferrin receptor protein 1, TfR, sTfR, p90, TfR1, Trfr, which belongs to the peptidase M28 family and M28B subfamily. CD71 /TFR contains one PA (protease associated) domain. CD71 / TfR1 is required for iron delivery from transferrin to cells. CD71 is a potential new target in cases of human leukomia & lymphoma. CD71 /TFRC / TfR has been shown to interact with GABARAP and HFE.

最新の進展

 
医薬品開発の進捗
  • 英語名:

    Transferrin receptor protein 1

  • カテゴリ:

  • 市販の医薬品数:

    1 詳細

  • 治験医薬品数:

    15 詳細

  • 最新の開発ステージ:

    Approved

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