GMP Human Truncated Vitronectin / VTN-N Protein

Vitronectin is a multifunctional glycoprotein present in the extracellular matrix and plasma. It plays important roles in various biological processes. It functions as an adhesive protein, facilitating cell attachment and spreading by binding to specific cell-surface receptors. Overall, Vitronectin is essential for maintaining the integrity and normal function of tissues and for coordinating various physiological processes in the body. It could support embryonic stem cell attachment and proliferation.

• Safe Recombinant Production: Produced via a recombinant E. coli expression system with an AOF process, ensuring a high‑purity profile.
• High Batch-to-Batch Consistency: Recombinant expression and purification deliver a single, defined component, avoiding the inherent variability of natural mixtures and variants to ensure exceptional reproducibility for scalable manufacturing.
• Validated Biological Activity: Demonstrates high functional performance, rigorously validated in stem cell culture applications.

• Quality Assurance: Global QMS with comprehensive and stringent QC release criteria.
• End-to-End GMP Compliance: Full manufacturing and QC under a cGMP system.
• Comprehensive Control of Adventitious Agents: Stringent biosafety from cell banks to final release.
• Comprehensive Regulatory Support: Includes RSF and DMF to meet global requirements.
• Resilient Supply Chain: Intelligent modular facilities ensure a stable global supply.
• Professional Support: Extensive manufacturing and application expertise to accelerate development.

GMP Human Truncated Vitronectin / VTN-N Protein (GMP-VINH19) is expressed from E. coli cells. It contains AA Val 62 - Leu 478 (Accession # P04004).

Less than 10 EU/mg, tested by the rFC method in compliance with USP <86> and Ph. Eur. 2.6.32.

<0.5 ng/µg of protein tested by ELISA.

<0.02 ng/μg of protein tested by qPCR.

Sterility testing was performed using the membrane filtration method in compliance with USP <71> and Ph. Eur. 2.6.1.

Negative

>95% as determined by SDS-PAGE.

Supplied as 0.2 μm filtered solution in PBS, 0.15 M Arginine, 0.5 mM EDTA, 250 mM N-Acetyl-L-cysteine, pH7.4 with protectants.

Contact us for customized product form or formulation.

2R (13 mm neck finish)

This product is supplied and shipped on dry ice.

Please avoid repeated freeze-thaw cycles.

• The product MUST be stored at -70°C or lower upon receipt;
• -70°C for 5 years under sterile conditions.