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TNF-alpha

概要

Name:Tumor necrosis factor α
Target Synonym:ICD1,Tumor necrosis factor,Tumor Necrosis Factor (TNF Superfamily, Member 2),Tumor Necrosis Factor Ligand 1F,Tumor Necrosis Factor-Alpha,TNF Superfamily, Member 2,TNF, Macrophage-Derived,TNF, Monocyte-Derived,APC1 Protein,TNLG1F,DIF,NTF,TNF-a,TNF-alpha,ICD2,N-terminal fragment,TNF,Tumor necrosis factor ligand superfamily member 2,Cachectin,TNFSF2,TNFA
Number of Launched Drugs:61
Number of Drugs in Clinical Trials:63
Lastest Research Phase:Approved

製品リスト製品比較と製品注文

製造番号 種類 製品説明 構造 純度 特徴
TNA-H82F3 Human Biotinylated Human TNF-alpha Protein, Fc,Avitag™ (MALS verified)
TNA-H82F3-structure
TNA-H82F3-sds
RAS-SP003 Human Human TNF-alpha ELISPOT Kit
RAS-SP004 Mouse Mouse TNF-alpha ELISPOT Kit
RES-A027 Human resDetect™ Human Tumor Necrosis Factor Alpha (TNF-α) ELISA Kit (Residue Testing)
EP-165 Human TNF-alpha : TNFR1[HRP] Inhibitor Screening ELISA Kit-Pre coated plate
GMP-TNAH23 Human GMP Human TNF-alpha Protein
GMP-TNAH23-structure
GMP-TNAH23-sds
GMP-TNAH23-hplc
TNA-M5257 Mouse Mouse TNF-alpha Protein, Fc Tag, active trimer (MALS verified)
TNA-M5257-structure
TNA-M5257-sds
EP-161 Human TNF-alpha : TNFR2 [Biotinylated] Inhibitor Screening ELISA Kit
TNA-H5255 Human Human TNF-alpha Protein, Fc Tag (MALS verified)
TNA-H5255-structure
TNA-H5255-sds
EP-147 Human TNF-alpha [Biotinylated] : TNFR2 Inhibitor Screening ELISA Kit
CRS-D002 Human Human Tumor Necrosis Factor Alpha (TNF-α) ELISA Assay Pair
TNA-M52H3 Mouse Mouse TNF-alpha Protein, His Tag
TNA-M52H3-structure
TNA-M52H3-sds
EP-143 Human TNF-alpha [Biotinylated] : TNFR1 Inhibitor Screening ELISA Kit
TNA-BLM494 Mouse Biotinylated Monoclonal Anti-TNF-alpha Antibody, human IgG1 (16H5) (MALS verified)
TNA-BLM494-sds
TNA-AM493 Mouse Monoclonal Anti-TNF-alpha Antibody, Human IgG1 (13B8) (MALS verified)
TNA-AM493-sds
TNA-AM494 Mouse Monoclonal Anti-TNF-alpha Antibody, Human IgG1 (16H5) (MALS verified)
TNA-AM494-sds
TNA-Y59 Mouse Monoclonal Anti-TNF-alpha Antibody, Mouse IgG1 (16H5)
TNA-Y58 Mouse Monoclonal Anti-TNF-alpha Antibody, Mouse IgG1 (13B8)
CRS-A002 Human ClinMax™ Human Tumor Necrosis Factor Alpha (TNF-α) ELISA Kit
TNA-C52H3 Canine Canine TNF-alpha Protein, His Tag, active trimer (MALS verified)
TNA-C52H3-structure
TNA-C52H3-sds
TNA-H5228 Human Human TNF-alpha Protein, His Tag, active trimer (MALS verified)
TNA-H5228-structure
TNA-H5228-sds
TNA-M82E9 Mouse Biotinylated Mouse TNF-alpha Protein, His,Avitag™, active trimer (MALS verified)
TNA-M82E9-structure
TNA-M82E9-sds
TNA-H82E3 Human Biotinylated Human TNF-alpha Protein, His,Avitag™, active trimer (MALS verified)
TNA-H82E3-structure
TNA-H82E3-sds
TNA-H8211 Human Biotinylated Human TNF-alpha Protein, epitope tag free, ultra sensitivity (primary amine labeling), active trimer (MALS verified)
TNA-H8211-structure
TNA-H8211-sds
TNA-H4211 Human Human TNF-alpha Protein, premium grade
TNA-H4211-structure
TNA-H4211-sds
ACRO Quality

生物活性データの一部

GMP-TNAH23-Cell-based assay
 TNF-alpha CELL

GMP Human TNF-alpha Protein (Cat. No. GMP-TNAH23) induces cytotoxicity effect on the WEHI-13VAR cells in the presence of the metabolic inhibitor actinomycin D. The specific activity GMP Human TNF-alpha Protein (Cat. No. GMP-TNAH23) is ≥ 2.00×10^7 IU/mg, which is calibrated against human TNF-alpha WHO International Standard (NIBSC code: 12/154) (QC tested).

TNA-H5228-Cell-based assay
 TNF-alpha CELL

Human TNF-alpha Protein, His Tag (Cat. No. TNA-H5228) induces cytotoxicity effect on the WEH1-13VAR cells in the presence of the metabolic inhibitor actinomycin D. The EC50 for this effect is 0.013-0.074 ng/mL (Routinely tested).

TNA-BLM494-SPR
 TNF-alpha SPR

Biotinylated Monoclonal Anti-TNF-alpha Antibody, human IgG1 (16H5) (Cat. No. TNA-BLM494) captured on CM5 chip via Anti-human IgG Fc antibodies surface can bind Human TNF-alpha, His Tag (Cat. No. TNA-H5228) with an affinity constant of 75.9 pM as determined in a SPR assay (Biacore 8K) (Routinely  tested).

TNA-AM493-SPR
 TNF-alpha SPR

Monoclonal Anti-TNF-alpha antibody, Human IgG1 (13B8) (Cat. No. TNA-AM493) captured on CM5 chip via Anti-human IgG Fc antibodies surface can bind Human TNF-alpha, His Tag (Cat. No. TNA-H5228) with an affinity constant of 0.133 nM as determined in a SPR assay (Biacore 8K) (Routly tested).

Synonym Name

DIF,TNF-alpha,TNFA,TNFSF2,cachexin,cachectin,TNFα

Background

Tumor necrosis factor alpha (TNFα)  is a cytokine produced primarily by monocytes and macrophages. It is found in synovial cells and macrophages in the tissues.The primary role of TNFα is in the regulation of immune cells. TNFα is able to induce apoptotic cell death, to induce inflammation, and to inhibit tumorigenesis and viral replication. Dysregulation of TNFα production has been implicated in a variety of human diseases, including major depression, Alzheimer's disease and cancer. Recombinant TNFα is used as an immunostimulant under the INN tasonermin. TNFα can be produced ectopically in the setting of malignancy and parallels parathyroid hormone both in causing secondary hypercalcemia and in the cancers with which excessive production is associated.

Clinical and Translational Updates

公開薬物情報

Name Research Code Research Phase Company First Brand Name First Approved Country First Indication First Approved Company First Approved Date Indications Clinical Trials
Etanercept biosimilar (Hanwha Chemical) HD-203; MK-8953 Approved Hanwha Chemical Davictrel Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Arthritis, Psoriatic Details
Anti-tumour necrosis factor-alpha antibody Approved Materia Medica Holding Research And Production Company Artrofoon, Arthrofoon Arthritis, Rheumatoid; Osteoarthritis Details
Etanercept biosimilar (AryoGen Biopharma) Approved Aryogen Biopharma Altebrel Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic Details
Adalimumab biosimilar (Reliance Life Sciences) R-TPR-021 Approved Reliance Life Sciences Adfrar IB India Spondylitis, Ankylosing; Arthritis, Rheumatoid; Colitis, Ulcerative; Psoriasis; Arthritis, Psoriatic Torrent Pharma, Reliance Life Sciences 2016-01-12 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Colitis, Ulcerative; Arthritis, Psoriatic Details
Certolizumab pegol PHA-738144; CDP-870; CZP Approved Ucb 希敏佳, Cimzia, Cimziat United States Crohn Disease Ucb Inc 2008-04-22 Non-radiographic axial spondyloarthritis; Infertility, Male; Polyarticular Juvenile Idiopathic Arthritis; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Spondylarthropathies; Spondylarthritis; Psoriasis; Arthritis, Psoriatic; Cystitis, Interstitial; Colitis, Ulcerative; Osteoarthritis, Spine; Crohn Disease; Plaque psoriasis Details
Etanercept biosimilar (Nanogen Biopharmaceutical) Approved Nanogen Biopharmaceutical Co Nanercept Vietnam Arthritis, Rheumatoid; Psoriasis Nanogen Biopharmaceutical Co 2019-01-01 Arthritis, Rheumatoid; Psoriasis Details
Infliximab Biosimilar (Genor Biopharma) GB-242 Approved Genor Biopharma Co Ltd 佳佑健 Mainland China Arthritis, Rheumatoid; Colitis, Ulcerative; Spondylitis, Ankylosing; Crohn Disease; Psoriasis Yuxi Genor Biotechnology Co Ltd 2022-02-23 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis; Colitis, Ulcerative; Crohn Disease Details
Etanercept biosimilar (Mochida) LBEC-0101 Approved Mochida Pharmaceutical Co Ltd Japan Arthritis, Juvenile; Arthritis, Rheumatoid null 2018-01-19 Arthritis, Rheumatoid; Arthritis, Juvenile Details
Adalimumab biosimilar (Amgen) ABP-501 Approved Amgen Inc Amjevita, Amgevita, Solymbic United States Colitis, Ulcerative; Crohn Disease; Psoriasis; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid Amgen Inc 2016-09-23 Non-radiographic axial spondyloarthritis; Polyarticular Juvenile Idiopathic Arthritis; Arthritis, Rheumatoid; Pediatric Crohn's disease; Spondylitis, Ankylosing; Arthritis, Juvenile; Pediatric ulcerative colitis; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Hidradenitis Suppurativa; Uveitis; Plaque psoriasis; Crohn Disease Details
Etanercept biosimilar (PROBIOMED) Approved Probiomed Infinitam Mexico Arthritis, Rheumatoid Probiomed 2014-01-01 Arthritis, Rheumatoid Details
Adalimumab biosimilar (Fresenius Kabi) MSB-11022 Approved Merck Serono, Fresenius Kabi Ag Idacio, Kromeya EU Crohn Disease; Uveitis; Hidradenitis Suppurativa; Psoriasis; Arthritis, Psoriatic Fresenius Kabi Deutschland Gmbh 2019-04-02 Non-radiographic axial spondyloarthritis; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Colitis, Ulcerative; Arthritis, Psoriatic; Uveitis; Hidradenitis Suppurativa; Plaque psoriasis; Crohn Disease Details
Etanercept biosimial (Sandoz) GP-2015 Approved Clariant Produkte (Schweiz) Ag Erelzi United States Psoriasis; Arthritis, Rheumatoid; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile Sandoz 2016-08-30 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic; Plaque psoriasis Details
Adalimumab biosimilar (Sinocelltech) SCT-630 Approved SinoCelltech Ltd 安佳润 Mainland China Arthritis, Juvenile; Crohn Disease; Pediatric Crohn's disease; Arthritis, Rheumatoid; Uveitis; Psoriasis; Spondylitis, Ankylosing SinoCelltech Ltd 2023-06-07 Pediatric Crohn's disease; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Uveitis; Crohn Disease; Plaque psoriasis Details
Lenalidomide IMID-5013; CDC-5013; CDC-501; CC-5013; IMiD-3; ENMD-0997; STAR-LLD Approved Celgene Corp Revimid (former Brand Name), 瑞复美, Revlimid, Leavdo United States Myelodysplastic Syndromes Bristol Myers Squibb Srlcompany 2005-12-27 Lymphoma, T-Cell, Peripheral; Optic Nerve Glioma; Intestinal Neoplasms; Immunoproliferative Small Intestinal Disease; Solid tumours; Bone Marrow Neoplasms; Lymphoma, B-Cell, Marginal Zone; Kidney Neoplasms; Leukemia; Liver Neoplasms; Hematologic Diseases; Leukemia, Erythroblastic, Acute; Leukemia, Promyelocytic, Acute; Leukemia, Myeloid; Ependymoma; HIV Infections; Ovarian Neoplasms; Medulloblastoma; Leukemia, Hairy Cell; Anemia; Paraproteinemias; Pain; Polycythemia Vera; Plaque, Amyloid; Rhabdoid Tumor; Anemia, Refractory, with Excess of Blasts; Glioblastoma; Smoldering Multiple Myeloma; Anemia, Refractory; Lymphoma, Large B-Cell, Diffuse; Hodgkin Disease; Myelodysplastic Syndromes; Hypothalamic Neoplasms; Neoplasms; Leukemia-Lymphoma, Adult T-Cell; Plasmacytoma; Blood Protein Disorders; Graft vs Host Disease; Leukemia, Myelomonocytic, Chronic; Leukemia, Myelomonocytic, Acute; Nerve Degeneration; Lymphomatoid Granulomatosis; Pancreatic Neoplasms; Multiple Myeloma; Leukemia, Megakaryoblastic, Acute; Oligodend Details
Etanercept biosimilar (Amega Biotech) Approved Amega Biotech Enerceptan Argentina Arthritis, Rheumatoid Amega Biotech 2012-01-01 Arthritis, Rheumatoid Details
Infliximab biosimilar (Reliance Life Sciences) BOW-015; R-TPR-015 Approved Epirus Biopharmaceuticals Inc Infimab Arthritis, Rheumatoid Details
Adalimumab biosimilar (Celltrion) CT-P17 Approved Celltrion Inc Yuflyma EU Arthritis, Psoriatic; Psoriasis; Arthritis, Juvenile; Plaque psoriasis; Pediatric Crohn's disease; Spondylitis, Ankylosing; Pediatric ulcerative colitis; Crohn Disease; Uveitis; Arthritis, Rheumatoid; Hidradenitis Suppurativa; Colitis, Ulcerative Celltrion Healthcare Hungary Kft 2021-02-11 Spondylitis, Ankylosing; Pediatric Crohn's disease; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Pediatric ulcerative colitis; Arthritis, Psoriatic; Colitis, Ulcerative; Hidradenitis Suppurativa; Uveitis; Plaque psoriasis; Crohn Disease Details
Etanercept biosimilar (Intas Biopharmaceuticals) Approved Intas Biopharmaceuticals Intacept India Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid; Psoriasis Intas Biopharmaceuticals 2015-03-01 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic Details
Infliximab biosimilar (Amgen) ABP-710 Approved Amgen Inc Avsola United States Pediatric ulcerative colitis; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Pediatric Crohn's disease; Plaque psoriasis Amgen Inc 2019-12-06 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Pediatric Crohn's disease; Pediatric ulcerative colitis; Arthritis, Psoriatic; Colitis, Ulcerative; Crohn Disease; Plaque psoriasis Details
Adalimumab biosimilar (LG Life Sciences) LBAL Approved Lg Chemical Ltd, Mochida Pharmaceutical Co Ltd Japan Arthritis, Rheumatoid; Psoriasis; Arthritis, Psoriatic; Arthritis, Juvenile; Colitis, Ulcerative; Spondylitis, Ankylosing; Behcet Syndrome; Uveitis, Intermediate; Uveitis, Posterior; Panuveitis; Crohn Disease Mochida Pharmaceutical Co Ltd 2021-03-23 Uveitis, Intermediate; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Uveitis, Posterior; Behcet Syndrome; Panuveitis; Crohn Disease Details
Adalimumab biosimilar (Boehringer Ingelheim) BI-695501 Approved C.H. Boehringer Sohn Ag & Co. Kg Cyltezo United States Colitis, Ulcerative; Crohn Disease; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid; Psoriasis Boehringer Ingelheim Gmbh 2017-08-25 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Colitis, Ulcerative; Arthritis, Psoriatic; Hidradenitis Suppurativa; Uveitis; Crohn Disease Details
Golimumab CNTO-148; rTNV148B Approved Johnson & Johnson Innovative Medicine Simponi/Simponi aria, Simponi, Simponi aria United States Spondylitis, Ankylosing; Arthritis, Psoriatic; Arthritis, Rheumatoid Centocor Ortho Biotech Inc 2009-04-24 Non-radiographic axial spondyloarthritis; Diabetes Mellitus, Type 1; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Colitis, Ulcerative; Arthritis, Psoriatic; Asthma; Labyrinth Diseases; Crohn Disease Details
Adalimumab biosimilar (Mylan/Biocon) BMO-2; MYL-1401-A Approved Biocon Ltd United States Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Plaque psoriasis; Arthritis, Psoriatic Mylan Pharmaceuticals Inc 2020-07-06 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Colitis, Ulcerative; Arthritis, Psoriatic; Hidradenitis Suppurativa; Crohn Disease; Plaque psoriasis Details
Luminol sodium MP-1032 Approved Selvim, Metrio Immune System Diseases; Psoriasis null 1997-01-01 Coronavirus Disease 2019 (COVID-19); Immune System Diseases; Psoriasis Details
Adalimumab biosimilar (Innovent Biologics) IBI-303 Approved Innovent Biologics(Suzhou) Co Ltd 苏立信 Mainland China Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis Innovent Biologics(Suzhou) Co Ltd 2020-09-02 Pediatric Crohn's disease; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Uveitis; Crohn Disease; Plaque psoriasis Details
Infliximab biosimilar (Pfizer) PF-6438179; GP-1111; PF-06438179 Approved Pfizer Inc Ixifi, Zessly EU Pediatric Crohn's disease; Pediatric ulcerative colitis; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Psoriasis; Arthritis, Psoriatic Pfizer Europe Ma Eeig 2013-09-09 Pediatric Crohn's disease; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Pediatric ulcerative colitis; Psoriasis; Colitis, Ulcerative; Arthritis, Psoriatic; Crohn Disease; Plaque psoriasis Details
Adalimumab biosimilar (Bio-Thera Solutions) BAT-1406 Approved Bio-Thera Solutions Ltd 格乐立 Mainland China Spondylitis, Ankylosing; Arthritis, Rheumatoid; Crohn Disease; Uveitis; Psoriasis Bio-Thera Solutions Ltd 2019-11-04 Non-radiographic axial spondyloarthritis; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Uveitis; Crohn Disease Details
Adalimumab biosimilar (Alvotech) AVT-02 (Alvotech) Approved Alvotech hf SIMLANDI, Ardalicip, Ciptunec, HUKYNDRA, LIBMYRIS EU Uveitis; Hidradenitis Suppurativa; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Crohn Disease; Psoriasis; Colitis, Ulcerative Stada Arzneimittel Ag 2021-11-12 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Colitis; Psoriasis; Colitis, Ulcerative; Arthritis, Psoriatic; Uveitis; Hidradenitis Suppurativa; Inflammation; Crohn Disease; Plaque psoriasis Details
Adalimumab biosimilar (Biocad) BCD-057 Approved Biocad Russian Federation Psoriasis Biocad 2019-03-01 Psoriasis Details
Adalimumab biosimilar (Shanghai Henlius Biotech) HLX-03 Approved Shanghai Henlius Biotech Inc 汉达远 Mainland China Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis Shanghai Henlius Biotech Inc 2020-12-02 Uveitis, Intermediate; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Immune System Diseases; Psoriasis; Uveitis, Posterior; Plaque psoriasis; Panuveitis Details
Infliximab TA-650 Approved Johnson & Johnson Innovative Medicine Remicade, 类克, Avakine, CenTNF United States Crohn Disease Centocor 1998-08-24 Uveitis; Vitreoretinopathy, Proliferative; Diabetic macular oedema; Visual Acuity; Pediatric ulcerative colitis; Glaucoma; Arthritis, Psoriatic; Colitis, Ulcerative; Retinal Detachment; Aneurysm; Parapsoriasis; Psoriasis; Hidradenitis Suppurativa; Granulomatous Disease, Chronic; Pulmonary Disease, Chronic Obstructive; Crohn Disease; Stevens-Johnson Syndrome; Behcet Syndrome; Diabetic Retinopathy; Melanoma; Plaque psoriasis; Pediatric Crohn's disease; Polymyositis; Inflammatory Bowel Diseases; Macular Edema; Scleritis; Dermatomyositis; Giant Cell Arteritis; Pancreatitis; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Graft vs Host Disease; Non-radiographic axial spondyloarthritis; Vasculitis; Bipolar Disorder; Spondylarthropathies; Sarcoidosis; Coronavirus Disease 2019 (COVID-19); Mucocutaneous Lymph Node Syndrome; Polymyalgia Rheumatica; Stroke; Arthritis, Juvenile Details
Infliximab biosimilar (Shanghai Biomabs) CMAB-008; STI-002 Approved Shanghai Biomabs Pharmaceuticals Co Ltd 百类停, 类停 Mainland China Arthritis, Rheumatoid; Pediatric Crohn's disease; Crohn Disease; Spondylitis, Ankylosing; Colitis, Ulcerative; Psoriasis Taizhou Mabtech Pharmaceutical Co Ltd 2021-07-12 Arthritis, Rheumatoid; Pediatric Crohn's disease; Spondylitis, Ankylosing; Psoriasis; Colitis, Ulcerative; Crohn Disease Details
Infliximab biosimilar (Hisun Pharma) HS-626 Approved Zhejiang Hisun Pharmaceutical Co Ltd Mainland China Psoriasis Hisun Biopharmaceutical Co Ltd 2021-09-24 Psoriasis Details
Infliximab biosimilar (Bionovis/The Instituto Vital Brazil) Approved Bionovis, The Instituto Vital Brazil Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Crohn Disease Details
Etanercept biosimilar (Mylan) YLB-113 Approved Lupin Ltd, Mylan Nv Nepexto EU Plaque psoriasis; Arthritis, Juvenile; Arthritis, Rheumatoid; Spondylarthropathies; Spondylitis, Ankylosing; Arthritis, Psoriatic Biosimilar Collaborations Ireland Ltd 2020-05-20 Arthritis, Rheumatoid; Spondylarthropathies; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Psoriatic; Plaque psoriasis Details
Pomalidomide IMID-4047; CDC-394; CC-4047; IMiD-1 Approved Celgene Corp Pomalyst, Imnovid, Actimid, Pomalyst/Imnovid, 安跃 United States Multiple Myeloma Bristol-Myers Squibb Company 2013-02-08 Pulmonary Fibrosis; Atypical Squamous Cells of the Cervix; Sarcoma, Kaposi; Anemia, Sickle Cell; Neurofibromatosis 1; Lymphoma, Non-Hodgkin; Carcinoma, Small Cell; Waldenstrom Macroglobulinemia; Glioma; Primary Myelofibrosis; Sarcoma; Thrombocytosis; Prostatic Neoplasms; Lung Diseases, Interstitial; Medulloblastoma; Central Nervous System Neoplasms; Multiple Myeloma; Hodgkin Disease; Plasmacytoma; Kidney Diseases; Pancreatic Neoplasms; Immunoglobulin Light-chain Amyloidosis; Myeloproliferative Disorders; Graft vs Host Disease; Scleroderma, Systemic; Polycythemia Vera; Bone Marrow Neoplasms; Solid tumours Details
Adalimumab biosimilar (Jiangsu Zhonghe/Shanghai Junshi/Jiangsu T-Mab) 9MW-0113; 9MW0113; UBP-1211; 9-MW-0113; 9-MW0113 Approved Shanghai Junshi Biosciences Co Ltd, Jiangsu Zhonghe Pharmaceutical Technology Co Ltd, Jiangsu T-Mab Bio-Pharmaceuticals Co Ltd, Mabwell (Shanghai) Bioscience Co Ltd 君迈康 Mainland China Psoriasis; Arthritis, Rheumatoid; Spondylitis, Ankylosing Shanghai Junshi Biosciences Co Ltd 2022-03-01 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Pediatric Crohn's disease; Arthritis, Juvenile; Psoriasis; Uveitis; Crohn Disease Details
Adalimumab biosimilar (Samsung Bioepis) SB-5 Approved Samsung Bioepis Co Ltd Imraldi, Hadlima EU Uveitis; Hidradenitis Suppurativa; Arthritis, Psoriatic; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Plaque psoriasis; Pediatric Crohn's disease; Arthritis, Juvenile; Psoriasis; Pediatric ulcerative colitis Samsung Bioepis Nl Bv 2017-08-24 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Pediatric Crohn's disease; Arthritis, Juvenile; Psoriasis; Pediatric ulcerative colitis; Arthritis, Psoriatic; Colitis, Ulcerative; Uveitis; Hidradenitis Suppurativa; Crohn Disease; Plaque psoriasis Details
Adalimumab biosimilar (Fujifilm Kyowa Kirin Biologics/Mylan) FKB-327 Approved Fujifilm Kyowa Kirin Biologics Co Ltd Hulio EU Colitis, Ulcerative; Crohn Disease; Uveitis; Arthritis, Psoriatic; Hidradenitis Suppurativa; Spondylitis, Ankylosing; Arthritis, Rheumatoid Biosimilar Collaborations Ireland Ltd 2018-09-16 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Colitis, Ulcerative; Arthritis, Psoriatic; Uveitis; Hidradenitis Suppurativa; Crohn Disease Details
Etanercept biosimilar (Sunshine Guojian) 301S Approved Sunshine GuoJian Pharmaceutical (Shanghai) Co Ltd, Cipla Gmbh Yisaipu, 益赛普, Etanar, Etacept Mainland China Arthritis, Rheumatoid; Psoriasis; Spondylitis, Ankylosing Sunshine GuoJian Pharmaceutical (Shanghai) Co Ltd 2005-06-20 Non-radiographic axial spondyloarthritis; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Psoriasis Details
PG-201 PG-201 Approved Viromed Layla South Korea Osteoarthritis Pmg Pharm Co Ltd 2012-01-01 Osteoarthritis, Knee; Osteoarthritis Details
Adalimumab biosimilar (Sandoz) GP-2017 Approved Sandoz Hefiya, Hyrimoz, Halimatoz EU Sandoz Gmbh 2018-07-26 Non-radiographic axial spondyloarthritis; Polyarticular Juvenile Idiopathic Arthritis; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Uveitis; Hidradenitis Suppurativa; Crohn Disease; Plaque psoriasis Details
Edaravone/(+)-2-Decanol SIM-071201; Y-2 Approved Jiangsu Simcere Pharmaceutical Co Ltd Sanbexin, 三贝心, 三贝欣 Mainland China Stroke Nanjing Simcere Dongyuan Pharmaceutical Co Ltd 2020-07-29 Intracranial Hemorrhages; Brain Infarction; Cerebral Hemorrhage; Stroke; Alzheimer Disease; Cognitive Dysfunction; Amyotrophic Lateral Sclerosis; Cognition Disorders Details
Adalimumab biosimilar (CTTQ Pharma) TQZ-2301; TQZ2301 Approved Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd Mainland China Spondylitis, Ankylosing; Arthritis, Rheumatoid Jiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd 2022-01-18 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Colitis, Ulcerative; Arthritis, Psoriatic; Crohn Disease Details
Infliximab biosimilar (AXXO) Approved Axxo Russian Federation Crohn Disease; Autoimmune Diseases Axxo 2013-01-01 Autoimmune Diseases; Crohn Disease Details
Infliximab biosimilar (Celltrion) CT-P13 Approved Celltrion Inc ZYMFENTRA, Remsima, Flammegis, Inflectra, Inflectra/Remsima EU Spondylitis, Ankylosing; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Psoriasis; Arthritis, Psoriatic Celltrion Healthcare Hungary Kft 2013-09-10 Non-radiographic axial spondyloarthritis; Inflammatory Bowel Diseases; Pediatric Crohn's disease; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Hidradenitis Suppurativa; Crohn Disease; Plaque psoriasis Details
Adalimumab biosimilar (Zydus Cadila) ZRC-3197 Approved Zydus Cadila Exemptia, Adaly India Arthritis, Juvenile; Arthritis, Rheumatoid; Arthritis, Psoriatic; Spondylitis, Ankylosing Zydus Cadila 2014-12-09 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Arthritis, Psoriatic Details
Ozoralizumab PF-5230896; ATN-103; PF-05230896; TS-152 Approved Ablynx Nv ナノゾラ, Nanozora Japan Arthritis, Rheumatoid Taisho Pharmaceutical Co Ltd 2022-09-26 Arthritis, Rheumatoid Details
Opinercept E-11; ENIA-11 Approved Tsh Biopharm, Mycenax Biotech Inc TuNEX Taiwan Arthritis, Rheumatoid null 2017-01-01 Non-radiographic axial spondyloarthritis; Arthritis, Rheumatoid Details
Adalimumab biosimilar (Hisun Pharma) HS-016 Approved Zhejiang Hisun Pharmaceutical Co Ltd 安健宁 Mainland China Arthritis, Rheumatoid; Spondylitis, Ankylosing Hisun Biopharmaceutical Co Ltd 2019-12-06 Arthritis, Rheumatoid; Spondylitis, Ankylosing Details
Infliximab biosimilar (Merck & Co/Samsung Bioepis) SB-2 Approved Samsung Bioepis Co Ltd, Merck & Co Inc Renflexis, Flixabi EU Crohn Disease; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Spondylitis, Ankylosing; Arthritis, Rheumatoid Samsung Bioepis Nl Bv 2016-05-26 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Crohn Disease; Plaque psoriasis Details
Andrographolide/Sodium Hydrogen Sulfite Approved Bacterial Infections Details
Adalimumab biosimilar (Coherus BioSciences) CHS-1420 Approved Coherus Biosciences Inc Yusimry United States Colitis, Ulcerative; Spondylitis, Ankylosing; Crohn Disease; Plaque psoriasis; Arthritis, Juvenile; Arthritis, Rheumatoid; Arthritis, Psoriatic Coherus Biosciences Inc 2021-12-17 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Colitis, Ulcerative; Arthritis, Psoriatic; Crohn Disease; Plaque psoriasis Details
Infliximab biosimilar (Nichiiko/Aprogen) NI-071; GS-071; GS-07; AP-07 Approved Nichi-Iko Pharmaceutical Co Ltd, Aprogen Japan Arthritis, Psoriatic; Arthritis, Rheumatoid; Colitis, Ulcerative; Crohn Disease; Psoriasis Nichi-Iko Pharmaceutical Co Ltd 2017-09-27 Arthritis, Rheumatoid; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Crohn Disease Details
Thalidomide NSC-66847; NSC-527179; K-17; VP-02; FPF-300; FPF300 Approved Celgene Corp Talizer, Thalidomide Celgene, Thalidomide Pharmion, Synovir, Thalomid, Thaled Mainland China Leprosy, Lepromatous; Multiple Myeloma Changzhou Pharmaceutical Factory 1982-01-01 HIV Wasting Syndrome; Angiodysplasia; Primary Myelofibrosis; Neuroectodermal Tumors, Primitive; Prostatitis; Colorectal Neoplasms; Osteosarcoma; Lymphoma, Mantle-Cell; Sarcoma, Ewing; Retinoblastoma; Erythema Nodosum; Drug Resistant Epilepsy; Xerostomia; Sarcoma; Pancreatitis, Chronic; Adenocarcinoma, Clear Cell; Lymphoma, Follicular; Arachnoiditis; Carcinoma, Adenosquamous; Gastrointestinal Hemorrhage; Cholangitis, Sclerosing; Prostatic Neoplasms; Pelvic Pain; Neoplasm Metastasis; Stomatitis; Burning Mouth Syndrome; Mycobacterium avium-intracellulare Infection; Amyotrophic Lateral Sclerosis; Melanoma; Myelodysplastic-Myeloproliferative Diseases; Carcinoma, Hepatocellular; Leukemia, Lymphocytic, Chronic, B-Cell; Vascular Malformations; Tuberculosis; Appendiceal Neoplasms; Lymphoma, Non-Hodgkin; Uterine Neoplasms; Anemia, Sideroblastic; Glioma; Leprosy, Lepromatous; Endometrial Neoplasms; Lung Neoplasms; Waldenstrom Macroglobulinemia; Kidney Neoplasms; Thalassemia; Carcinoid Tumor; Lupus Erythematosus, Discoid Details
Adalimumab biosimilar (Pfizer) PF-06410293 Approved Pfizer Inc Abrilada, Fyzoclad, Amsparity United States Arthritis, Psoriatic; Spondylitis, Ankylosing; Psoriasis; Arthritis, Rheumatoid; Colitis, Ulcerative; Arthritis, Juvenile; Crohn Disease Pfizer Inc 2019-11-15 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Hidradenitis Suppurativa; Uveitis; Crohn Disease Details
Etanercept biosimilar (Hisun-Pfizer Pharmaceuticals) Approved Hisun-Pfizer AnBaiNuo Mainland China Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Arthritis, Psoriatic Wyeth Europa Ltd 2010-02-26 Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Arthritis, Psoriatic Details
Adalimumab ABT-D2E7; LU-200134; D2E7 Approved Abbvie Inc Humira, Trudexa, 修美乐 United States Arthritis, Rheumatoid Abbvie Inc 2002-12-31 Uveitis, Posterior; Glomerulosclerosis, Focal Segmental; Colitis, Ulcerative; Osteoarthritis, Knee; Cystitis, Interstitial; Arthritis, Psoriatic; Asthma; Arthritis; Uveitis; Hidradenitis Suppurativa; Mucopolysaccharidosis VI; Mucopolysaccharidosis II; Nephrotic Syndrome; Osteoarthritis; Crohn Disease; Diabetic Retinopathy; Choroidal Neovascularization; Plaque psoriasis; Panuveitis; Spondylarthritis; Pain; Prostatic Hyperplasia; Pyoderma Gangrenosum; Uveitis, Intermediate; Pouchitis; Arthritis, Rheumatoid; Pediatric Crohn's disease; Sarcoidosis; Non-radiographic axial spondyloarthritis; Spondylitis, Ankylosing; Coronavirus Disease 2019 (COVID-19); Dupuytren Contracture; Arthritis, Juvenile; Mucopolysaccharidosis I; Nephrosis, Lipoid; Psoriasis; Periarthritis Details
Etanercept biosimilar (Qilu Pharmaceutical) QL-0902 Approved Qilu Pharmaceutical Co Ltd Mainland China Qilu Pharmaceutical Co Ltd 2023-12-19 Arthritis, Rheumatoid; Spondylitis, Ankylosing Details
Etanercept biosimilar (Samsung Bioepis) SB-4 Approved Samsung Bioepis Co Ltd Eticovo, Benepali EU Arthritis, Psoriatic; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Plaque psoriasis Samsung Bioepis Nl Bv 2016-01-13 Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Psoriasis; Arthritis, Psoriatic; Plaque psoriasis Details
Etanercept TNR-001 Approved Amgen Inc, Pfizer Inc Lifmior, 恩利, Enbrel EU Plaque psoriasis; Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Psoriatic; Arthritis, Juvenile Pfizer Europe Ma Eeig 2000-02-02 Obesity; Pulmonary Fibrosis; Psoriasis; Myositis, Inclusion Body; Prostatic Neoplasms; Temporomandibular Joint Disorders; Arthritis, Psoriatic; Bone Neoplasms; Lichen Planus; Alzheimer Disease; Asthma; Hidradenitis Suppurativa; Respiratory Distress Syndrome, Adult; Inflammation; Cachexia; Arthritis; Lung Neoplasms; Uveitis; Plaque psoriasis; Vitiligo; Neoplasm Metastasis; Acute Lung Injury; Kidney Failure, Chronic; Stomatitis; Spondylitis, Ankylosing; Granulomatosis with Polyangiitis; Leukemia; Non-radiographic axial spondyloarthritis; Bronchiolitis Obliterans; Solid tumours; Tinnitus; HIV Infections; Lupus Erythematosus, Discoid; Rejection of lung transplantation; Arthritis, Rheumatoid; Fanconi Anemia; Diabetes Mellitus, Type 1; Vasculitis; Graft vs Host Disease; Lupus Erythematosus, Cutaneous; Synovitis; Sjogren's Syndrome; Anorexia; Metabolic Syndrome; Spondylarthritis; Chronic Urticaria; Small Cell Lung Carcinoma; Arthritis, Juvenile Details

臨床試験情報

Name Research Code Research Phase Company Indications Clinical Trials
Adalimumab biosimilar (Danhong Pharma) BC-002 Phase 3 Clinical Shandong Danhong Pharmaceutical Co Ltd Spondylitis, Ankylosing; Arthritis, Rheumatoid Details
Adalimumab biosimilar (Hetero Drugs) Phase 3 Clinical Hetero Drugs Ltd Arthritis, Rheumatoid Details
Efprezimod alfa CD24-Fc; HAS-CD24; CD24-Fc-IgG; MK-7110; MK7110 Phase 3 Clinical Oncoimmune Inc Solid tumours; Hematopoietic stem cell transplantation (HSCT); Leukemia; HIV Infections; Graft vs Host Disease; Myelodysplastic Syndromes; Coronavirus Disease 2019 (COVID-19); Precursor Cell Lymphoblastic Leukemia-Lymphoma; Dyslipidemias; Leukemia, Myeloid, Acute; Melanoma Details
Adalimumab biosimilar (CinnaGen) Phase 3 Clinical Cinnagen Arthritis, Rheumatoid Details
Adalimumab biosimilar (Hualan Biological Engineering) Phase 3 Clinical Hualan Genetic Engineering Co Ltd Spondylitis, Ankylosing; Psoriasis; Arthritis Details
Etanercept biosimilar (Clover Biopharmaceuticals) SCB-808 Phase 3 Clinical Arthritis, Rheumatoid; Spondylitis, Ankylosing; Thrombocytopenia Details
Golimumab biosimilar (Bio-thera) BAT-2506 Phase 3 Clinical Bio-Thera Solutions Ltd Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis; Arthritis, Psoriatic; Arthritis Details
Adalimumab biosimilar (Oncobiologics) ONS-3010; HOT-3010; Onco-3010 Phase 3 Clinical Outlook Therapeutics Inc Spondylitis, Ankylosing; Psoriasis; Arthritis; Plaque psoriasis Details
Recombinant anti-TNFα monoclonal antibody (Wuhan Institute of Biological Products) Phase 3 Clinical Wuhan Institute Of Biological Products Co Ltd Plaque psoriasis Details
Adalimumab biosimilar (Tonghua Dongbao Pharmaceutical) Phase 3 Clinical Tonghua Dongbao Pharmaceutical Co Ltd Arthritis, Rheumatoid; Plaque psoriasis Details
Mufemilast Hemay-005 Phase 3 Clinical Tianjin Hemay Pharmaceutical Co Ltd, Hainan Hailing Chemipharma Corporation Ltd Spondylitis, Ankylosing; Psoriasis; Arthritis, Psoriatic; Colitis, Ulcerative; Pulmonary Disease, Chronic Obstructive; Behcet Syndrome; Plaque psoriasis; Dermatitis, Atopic Details
Tanfanercept HBM-9036; HL-036 Phase 3 Clinical Hanall Dry Eye Syndromes; Xerophthalmia Details
Adalimumab biosimilar (Mabscale) Phase 3 Clinical Mabscale LLC Psoriasis; Plaque psoriasis Details
Golimumab biosimilar( Alvotech) AVT05; AV-T05 Phase 3 Clinical Alvotech Swiss Ag Arthritis, Rheumatoid Details
Adalimumab biosimilar(Incepta) Phase 3 Clinical Incepta Pharmaceuticals Ltd Arthritis, Rheumatoid Details
Hemay007 Hemay-007 Phase 2 Clinical Tianjin Hemay Bio-Tech Co Ltd Inflammatory Bowel Diseases; Arthritis, Rheumatoid; Colitis, Ulcerative Details
Recombinant anti-TNFα monoclonal antibody (Livzon Group) AT-132; LZM-001 Phase 2 Clinical Livzon Pharmaceutical Group Inc Arthritis, Rheumatoid Details
CC-10015 CC-10015 Phase 2 Clinical Celgene Corp Sarcoidosis; Multiple Myeloma; Lupus Erythematosus, Systemic Details
EYS-606 EYS-606 Phase 2 Clinical Eyevensys SAS Uveitis Details
Dovramilast CC-11050; AMG-634 Phase 2 Clinical Celgene Corp HIV Infections; Lupus Erythematosus, Cutaneous; Tuberculosis Details
Licaminlimab OCS-02; ESBA-1622; LME-636 Phase 2 Clinical Oculis Pharma, Alcon Dry Eye Syndromes; Uveitis, Anterior Details
XTMAB-16 XTMAB-16 Phase 2 Clinical Xentria Inc Sarcoidosis, Pulmonary Details
SAR-442970 SAR-442970 Phase 2 Clinical Sanofi Inflammation; Hidradenitis Suppurativa Details
Guselkumab/Golimumab JNJ-78934804 Phase 2 Clinical Janssen Research & Development Llc Colitis, Ulcerative; Crohn Disease Details
Isomyosamine MYMD-1 Phase 2 Clinical Mymd Pharmaceuticals Inc Depression; Anxiety; Hashimoto Disease; Frailty; Coronavirus Disease 2019 (COVID-19); Arthritis, Rheumatoid; Healthy Aging; Inflammation; Sarcopenia Details
ME-3183 ME-3183 Phase 2 Clinical Meiji Seika Pharma Co Ltd Psoriasis; Plaque psoriasis Details
OPS-2071 OPS-2071 Phase 2 Clinical Otsuka Pharmaceutical Co Ltd Enteritis; Irritable Bowel Syndrome; Crohn Disease Details
Adalimumab biosimilar (Eastern Biotech) JY-026 Phase 1 Clinical Beijing Eastern Biotech Co Ltd Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Psoriasis; Crohn Disease Details
Recombinant human anti-TNFα monoclonal antibody (Qilu Pharmaceutical) Phase 1 Clinical Qilu Pharmaceutical Co Ltd Arthritis, Rheumatoid; Spondylitis, Ankylosing Details
Recombinant human monoclonal antibody specific for human tumor necrosis factor (North China Pharmaceutical) Phase 1 Clinical North China Pharmaceutical Company Ltd Spondylitis, Ankylosing; Arthritis, Rheumatoid; Psoriasis Details
Certolizumab (Intrexon) AG-014 Phase 1 Clinical Intrexon Corporation Inflammatory Bowel Diseases Details
Adalimumab biosimilar (Weimingdamu Biotech) Phase 1 Clinical Anhui Weiming Damu Biomedicine Co Ltd Arthritis, Rheumatoid Details
Anti-tumour necrosis factor alpha (Livzon) Phase 1 Clinical Livzon Pharmaceutical Group Inc Autoimmune Diseases Details
Etanercept biosimilar (Suzhou Genemen Biotech) BF-02; GM-02 Phase 1 Clinical Suzhou Genemen Biotech Co Ltd Spondylitis, Ankylosing Details
Infliximab biosimilar (Ospedale San Raffaele) Phase 1 Clinical Ospedale San Raffaele Takayasu Arteritis Details
Recombinant anti-TNFα antibody (Shanghai Xiesheng Medicine) Phase 1 Clinical Shanghai Harmony Pharmaceutical Technology Co Ltd Details
JNJ-61178104 JNJ-61178104 Phase 1 Clinical Johnson & Johnson Innovative Medicine Autoimmune Diseases Details
Adalimumab biobetter(Xencor/Zenas Biopharma) XmAb-6755; ZB-002 Phase 1 Clinical Xencor Inc, Zenas BioPharma Arthritis, Rheumatoid; Autoimmune Diseases of the Nervous System Details
JNJ-63823539 JNJ-63823539 Phase 1 Clinical Johnson & Johnson Innovative Medicine Arthritis, Rheumatoid Details
Adalimumab biosimilar (Laboratorios Richmond) Phase 1 Clinical Laboratorios Richmond Details
NEX-20A NEX-20A Phase 1 Clinical Nanexa AB Multiple Myeloma Details
IA-14069 IA-14069 Phase 1 Clinical ILAb Co Ltd Arthritis, Rheumatoid Details
SOR-102 SOR-102 Phase 1 Clinical Sorriso Pharmaceuticals Inc Inflammatory Bowel Diseases; Colitis, Ulcerative Details
Monoclonal Antibody (Mab) sB24M Phase 1 Clinical Swiss Biopharma Med GmbH Pyoderma Gangrenosum; Pyoderma Details
ND-009 ND-009 Phase 1 Clinical Numab Therapeutics Ag, Tillotts Pharma Ag Inflammation Details
Adalimumab biosimilar (DZM Biotech) Phase 1 Clinical Dzm Biotech Ltd Arthritis, Rheumatoid Details
Igrelimogene litadenorepvec PM-1016; PM1016; TILT-123 Phase 1 Clinical Tilt Biotherapeutics Ltd Solid tumours; Ovarian Neoplasms; Squamous Cell Carcinoma of Head and Neck; Small Cell Lung Carcinoma; Peritoneal Neoplasms; Lung Neoplasms; Fallopian Tube Neoplasms; Melanoma; Carcinoma, Hepatocellular Details
Adalimumab biosimilar (Prestige BioPharma) PBP-1502 Phase 1 Clinical Prestige BioPharma Ltd Details
Adalimumab biosimilar (AXXO) Clinical Axxo Arthritis, Rheumatoid; Arthritis, Psoriatic Details
IBPM005IX (Inbiopro Solutions) Clinical Inbiopro Solutions Spondylitis, Ankylosing; Arthritis, Rheumatoid; Arthritis, Juvenile; Arthritis, Psoriatic; Crohn Disease Details
Etanercept (Neurokine Pharmaceuticals) NP-1; NK-001 Clinical Pivot Pharmaceuticals Cognition Disorders Details
Adalimumab biosimilar(BioXpress) BX-2922; BXT-2922 Clinical Bioxpress Therapeutics Sa Pediatric Crohn's disease; Arthritis, Rheumatoid; Spondylitis, Ankylosing; Arthritis, Juvenile; Colitis, Ulcerative; Arthritis, Psoriatic; Hidradenitis Suppurativa; Uveitis; Crohn Disease Details
Wogonin Shandong Buchang Pharmaceuticals Co Ltd, Hefei Cosource Medicine Technology, Daewoong Pharmaceutical Co Ltd, China Pharmaceutical University Details

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