言語を選択

ADORA2A

ADORA2A 詳細

英語名	Adenosine A2a receptor	市販薬剤の数	53
治験薬の数	23	ターゲットの別称	Adenosine receptor A2a，ADORA2A，Adenosine A2a Receptor，ADORA2，Adenosine Receptor Subtype A2a，A2aR，RDC8，Receptor， Adenosine A2A
研究＆開発段階	Approved

英語名	Adenosine A2a receptor
ターゲットの別称	Adenosine receptor A2a，ADORA2A，Adenosine A2a Receptor，ADORA2，Adenosine Receptor Subtype A2a，A2aR，RDC8，Receptor， Adenosine A2A
市販薬剤の数	53
治験薬の数	23
研究＆開発段階	Approved

ADORA2A 製品リスト

属性
Protein (2)
製品ライブラリ
オンライン (2)
種
Human (2)
タグ
- (1)His Tag & Flag Tag (1)
マーカー
Unconjugated (2)

製品番号	種	発現システム	製品説明	タンパク質の構造	純度	特性
ADA-H52D3	Human	HEK293	Human ADORA2A Protein, Flag,His Tag (Detergent)
ADA-H52P4	Human	HEK293	Human ADORA2A Full Length Protein (VLP)

総数量2

ADORA2Aバックグランド

Adenosine Receptor Subtype A2a (ADORA2A) is a G-protein coupled adenosine receptor encoded by the ADORA2A gene. It is mainly involved in pathophysiological processes including neuroinflammation, synaptic plasticity in glutamatergic synapses and neurogenesis.

ADORA2A分子の別称

ADORA2A,adenosine A2a receptor,A2aR, ADORA2, RDC8

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Naproxen/Caffeine	BAY-2880376	Phase 3 Clinical	Bayer AG	Pain, Postoperative	詳細
Imaradenant	AZD-4635; HTL-1071	Phase 2 Clinical	Nxera Pharma UK Ltd	Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Solid tumours	詳細
Ciforadenant	CPI-444; V-81444	Phase 2 Clinical	Vernalis (R&D) Ltd	Attention Deficit Disorder with Hyperactivity; Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Multiple Myeloma; Neoplasms; Parkinson Disease	詳細
Caffeinol		Phase 2 Clinical	Cardium Therapeutics	Alcoholic Intoxication; Alcoholism; Carcinoma, Non-Small-Cell Lung; Disruptive, Impulse Control, and Conduct Disorders; Ischemic Stroke	詳細
Etrumadenant	AB-928; GS-0928	Phase 2 Clinical	Arcus Biosciences Inc	Breast Neoplasms; Carcinoma, Merkel Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Colorectal Neoplasms; Endometrial Neoplasms; Esophageal Neoplasms; Head and Neck Neoplasms; Hormone-Resistant Prostate Neoplasms; Hypopharyngeal Neoplasms; Laryngeal Neoplasms; Lung Neoplasms; Melanoma; Mouth Neoplasms; Neoplasm Metastasis; Oral Squamous Cell Carcinoma; Oropharyngeal Neoplasms; Oropharyngeal Squamous Cell Carcinoma (OPSCC); Ovarian Neoplasms; Pharyngeal Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Rectal Neoplasms; Squamous Cell Carcinoma of Head and Neck; Stomach Neoplasms; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms	詳細
PORT-8	PORT-8; TT-53	Phase 2 Clinical	Tarus Therapeutics Inc	Solid tumours	詳細
ND10(Theialife Inc)	ND-10; ND10	Phase 2 Clinical	Theialife Inc	Cataract; Dry Eye Syndromes; Myopia	詳細
PORT-6	PORT-6; TT-10	Phase 2 Clinical	Impetis Biosciences Ltd	Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Colorectal Neoplasms; Endometrial Neoplasms; Neoplasms; Ovarian Neoplasms; Prostatic Neoplasms, Castration-Resistant; Squamous Cell Carcinoma of Head and Neck	詳細
MK-1088	MK-1088	Phase 2 Clinical	Merck Sharp & Dohme LLC	Solid tumours	詳細
VG081821AC	VG081821AC; VG-081821AC	Phase 2 Clinical	Zhejiang Vimgreen Pharmaceuticals Ltd	Metabolic Dysfunction-Associated Steatotic Liver Disease; Parkinson Disease	詳細
ILB-2109	WTS-001; ILB-2109	Phase 2 Clinical	Hangzhou Wutong Tree Pharmaceutical Co Ltd	Carcinoma, Non-Small-Cell Lung; Endometrial Neoplasms; Head and Neck Neoplasms; Hodgkin Disease; Melanoma; Nasopharyngeal Carcinoma; Neoplasms; Ovarian Neoplasms; Sarcoma; Solid tumours; Triple Negative Breast Neoplasms; Uterine Cervical Neoplasms	詳細
PBF-999	PBF-999	Phase 1 Clinical	Palobiofarma Sl	Huntington Disease; Neoplasms	詳細
[18F]MNI-444	[18F]MNI-444	Phase 1 Clinical	Invicro Llc	Diagnostic agents	詳細
SHR-5126	SHR-5126	Phase 1 Clinical	Jiangsu Hengrui Medicine Co Ltd	Neoplasms	詳細
Taminadenant	NIR-178; PBF-509	Phase 1 Clinical	Palobiofarma Sl	Carcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Colorectal Neoplasms; Head and Neck Neoplasms; Lymphoma, Large B-Cell, Diffuse; Melanoma; Ovarian Neoplasms; Pancreatic Neoplasms; Parkinson Disease; Prostatic Neoplasms, Castration-Resistant; Solid tumours; Triple Negative Breast Neoplasms	詳細
ST-4206	ST-4206	Phase 1 Clinical	Alfasigma Spa	Parkinson Disease	詳細
CKD-512	CKD-512	Phase 1 Clinical	Chong Kun Dang Pharmaceutical Corp	Neoplasms; Solid tumours	詳細
JNJ-86974680	JNJ-86974680	Phase 1 Clinical	Johnson & Johnson Enterprise Innovation Inc	Carcinoma, Non-Small-Cell Lung; Prostatic Neoplasms	詳細
YZJ-5053	YZJ5053; YZJ-5053	Phase 1 Clinical	Shanghai Haiyan Pharmaceutical Technology Co Ltd	Neoplasm Metastasis; Solid tumours	詳細
CT-1500	CT-1500	Phase 1 Clinical	Circadian Technologies Ltd		詳細
DZD-2269	DZD-2269	Phase 1 Clinical	Dizal Pharmaceutical Co Ltd	Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant	詳細
INCB-106385	INCB-106385	Phase 1 Clinical	Incyte Corp	Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Gastrointestinal Neoplasms; Ovarian Neoplasms; Prostatic Neoplasms, Castration-Resistant; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms	詳細
CS-3005	CS-3005	Phase 1 Clinical	Cstone Pharmaceuticals (Suzhou) Co Ltd	Solid tumours	詳細

市販薬剤に関する情報

英語名	研究コード	研究開発ステージ	会社	オリジナル製品名	最初に承認をした国	最初の適応症	最初に承認を受けた会社	承認された日付	適応症	臨床試験
Regadenoson Hydrate	CVT-3146	Approved	Astellas Pharma Inc	Rapiscan, 海诺生, Lexiscan	United States	Contrast agents	Astellas Pharma Inc	2008-04-10	Anemia, Sickle Cell; Astrocytoma; Cardiovascular contrast agents; Cardiovascular Diseases; Contrast agents; Coronary Artery Disease; Coronavirus Disease 2019 (COVID-19); Diagnostic agents; Glioblastoma; Glioma; Heart Diseases; Myocardial Ischemia; Oligodendroglioma; Pneumonia; Rejection of lung transplantation; Retinal Artery Occlusion	詳細
Caffeine/Ergotamine Tartrate		Approved	Novartis Pharma Ag	Cafergot	Japan	Vascular Headaches; Migraine Disorders; Tension-Type Headache	Nichi-Iko Pharmaceutical Co Ltd	1948-11-26	Migraine Disorders; Tension-Type Headache; Vascular Headaches	詳細
Oxtriphylline		Approved		Theocolin	Canada		null		Asthma	詳細
Caffeine/Metamizole Sodium/Dihydroergotamine Mesylate		Approved		Cefaliv					Migraine Disorders	詳細
Adenine		Approved		Leucon	Japan	Leukopenia	Ohara Pharmaceutical Co Ltd		Leukemia; Leukopenia	詳細
Acetaminophen/Butalbital/Caffeine/Codeine Phosphate		Approved	Actavis Laboratories Ut Inc		United States	Headache; Headache Disorders	Actavis Laboratories Ut Inc	1992-07-30	Headache; Headache Disorders	詳細
Istradefylline	KW-6002	Approved	Kyowa Hakko Kirin Co Ltd	Nourianz, Nouriast	Japan	Parkinson Disease	Kyowa Hakko Kirin Co Ltd	2013-03-25	Amyotrophic Lateral Sclerosis; Cognition Disorders; Hepatic Insufficiency; Movement Disorders; Parkinson Disease; Restless Legs Syndrome; Sleep Wake Disorders; Substance-Related Disorders	詳細
Sodium Citrate/Citric Acid/Dextrose/Monosodium phosphate/Adenine/Mannitol/Sodium Chloride		Approved								詳細
Sodium Citrate/Citric Acid/Dextrose		Approved								詳細
Sodium Citrate/Citric Acid/Dextrose/Monosodium phosphate/Adenine		Approved								詳細
Aspirin/Acetaminophen/Caffeine/Thiamine		Approved							Fever; Pain	詳細
Propranolol hydrochloride/Caffeine/Phenytoin Sodium		Approved			Mainland China		Hebei Tiancheng Pharmaceutical Co Ltd			詳細
Salicylamide/Acetaminophen/Caffeine		Approved							Arthralgia; Fever; Headache; Neuralgia; Rheumatic Diseases	詳細
Compound Paracetamol Caffeine and Pseudoephedrine Hydrochloride		Approved							Common Cold	詳細
Acetaminophen/Methylephedrine Hydrochloride/Dextromethorphan Hydrobromide/Chlorphenamine Maleate/Caffeine/Sulfogaiacol		Approved			Mainland China	Common Cold	Zhejiang Apeloa Kangyu Pharmaceutical Co Ltd		Common Cold	詳細
Dextromethorphan Hydrobromide/Chlorphenamine Maleate/Sodium Citrate/Ammonium Chloride/Caffeine		Approved		尔可芬					Cough	詳細
Acetaminophen/Caffeine/Codeine Phosphate/Diphenhydramine Hydrochloride		Approved		斯力帮					Headache	詳細
Ferric Ammonium Citrate/Vitamin B1/Sodium glycerophosphate/Caffeine		Approved							Ischemia	詳細
Norethidranum Dipropionas/Caffeine/Vitamin B6		Approved			Mainland China	Contraception	Huazhong Pharmaceutical Co Ltd	1981-01-01	Contraception	詳細
Acetaminophen/Propyphenazone/Caffeine		Approved		散利痛, 散列通					Common Cold	詳細
Quinine Hydrochloride Hydrate/Caffeine		Approved							Malaria	詳細
Dihydroergocryptine/Caffeine		Approved		洛斯宝, VASOBRAL					Diabetes Mellitus; Diabetic Retinopathy	詳細
Aminophenazone/Phenacetin/Caffeine		Approved							Fever; Pain	詳細
Aminophenazone/Caffeine/Calcium Glycerophosphate		Approved							Dysmenorrhea; Headache; Neuralgia	詳細
Acetaminophen/Caffeine/Chlorphenamine Maleate		Approved							Common Cold	詳細
Aminophenazone/Caffeine/Chlorphenamine Maleate		Approved							Common Cold; Headache; Neuralgia	詳細
Aspirin/Caffeine/Codeine Phosphate		Approved		柯克					Pain	詳細
Acetaminophen/Pseudoephedrine Hydrochloride/Caffeine		Approved							Common Cold	詳細
Aspirin/Acetaminophen/Caffeine/Chlorphenamine Maleate		Approved							Common Cold	詳細
Aspirin/Caffeine/Chlorphenamine Maleate/Tartaric Acid		Approved							Common Cold	詳細
Acetaminophen/Caffeine/Pseudoephedrine Hydrochloride/Chlorphenamine Maleate		Approved							Common Cold	詳細
Aminophenazone/Phenacetin/Caffeine/Phenobarbital		Approved							Migraine Disorders	詳細
Acetaminophen/Chlorphenamine Maleate/Caffeine/Guaifenesin		Approved							Common Cold	詳細
Acetaminophen/Amantadine Hydrochloride/Caffeine/Artificial Bezoar		Approved							Common Cold	詳細
Acetaminophen/Salicylamide/Pseudoephedrine Hydrochloride/Caffeine/Triprolidine Hydrochloride Hydrate		Approved		联邦菲迪乐					Common Cold	詳細
Sodium Benzoate/Caffeine		Approved							Central Nervous System Diseases	詳細
Aminophenazone/Caffeine		Approved							Fever	詳細
Antipyrine/Caffeine		Approved							Common Cold	詳細
Aspirin/Caffeine		Approved							Common Cold	詳細
Antipyrine/Caffeine/Citric Acid		Approved		米格来宁	Mainland China	Sedation	Mudanjiang Lingtai Medicdment Co Ltd, Xi'An Disai Biological Pharmaceutical Co Ltd, Heilongjiang Hasing Pharmaceutical Group Co Ltd, Huadong Medicine (Xi'An) Bodyguard Pharmaceutical Co Ltd	1982-01-01	Sedation	詳細
Aminophenazone/Acetaminophen/Caffeine/Chlorphenamine Maleate		Approved		克感敏, 扑感敏, 朴感敏					Common Cold	詳細
Acetaminophen/Caffeine/Ephedrine Hydrochloride/Diphenhydramine Hydrochloride		Approved							Influenza, Human	詳細
Acetaminophen/Caffeine/Chlorphenamine Maleate/Artificial Bezoar		Approved							Common Cold	詳細
Aspirin/Phenacetin/Caffeine		Approved							Arthralgia; Dysmenorrhea; Fever; Headache; Neuralgia; Toothache	詳細
Aspirin/Caffeine/Acetaminophen		Approved			United States	Migraine Disorders	Haleon PLC		Anesthesia; Migraine Disorders	詳細
Acetaminophen/Butalbital/Caffeine		Approved							Headache	詳細
Acetaminophen/Caffeine		Approved	Zentiva As		Mainland China	Pain	Sino--American Shanghai Squibb Pharmaceutical Ltd		Pain	詳細
Sodium glycerophosphate/Caffeine/Vitamin B/Phosphoric Acid/Niacin		Approved								詳細
Acetaminophen/Caffeine/Phenylephrine Hydrochloride/Chlorphenamine Maleate/Vitamin B		Approved								詳細
Acetaminophen/Chlorphenamine Maleate/Methylephedrine Hydrochloride/Sulfogaiacol/Caffeine		Approved			Mainland China	Common Cold	Hainan Sanfengyou Pharmaceutical Co Ltd	2006-05-16	Common Cold	詳細
Brompheniramine Maleate/Bromhexine Hydrochloride/Caffeine/Acetaminophen/Phenylephrine Hydrochloride		Approved							Common Cold	詳細
Acetaminophen/Amantadine Hydrochloride/Caffeine/Chlorphenamine Maleate/Artificial Bezoar		Approved		复方氨酚烷胺	Mainland China	Common Cold	null	1984-01-01	Common Cold	詳細
Caffeine		Approved							Apnea; Cocaine-Related Disorders; Cognitive Dysfunction; Consciousness; Delirium; Diabetes Complications; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Disorders of Excessive Somnolence; Fatigue; Fetal Membranes, Premature Rupture; Intermittent Claudication; Memory Disorders; Mental Fatigue; Parkinson Disease; Postoperative Cognitive Complications; Sexual Dysfunction, Physiological; Sleepiness; Spinal Cord Injuries	詳細