BST1 詳細
Molecule Name
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2
分子の別称
ADP-ribosyl cyclase 2, CD157
Drug Development Progress
治験薬の数0
市販薬剤の数0
研究＆開発段階Discontinued
ターゲットの別称
Bone Marrow Stromal Cell Antigen 1 Variant 2，BST1，Bone marrow stromal antigen 1，Bone Marrow Stromal Cell Antigen 1，ADP-Ribosyl Cyclase 2，Cyclic ADP-Ribose Hydrolase 2，NAD(+) Nucleosidase，CADPr Hydrolase 2，ADP-Ribosyl Cyclase/Cyclic ADP-Ribose Hydrolase 2，CD157 Antigen，EC 3.2.2.6，CD157，BST-1，EC:3.2.2.6
バックグランド
Bone marrow stromal cell antigen-1(BST-1) or CD157 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that belongs to the CD38 family. CD157 was discovered in a bone marrow stromal cell line where it facilitates pre-B-cell growth.BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be, at least in part, attributed to BST1 overexpression in the stromal cell population.
BST1 製品リスト
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