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Cadherin-17

Cadherin-17 詳細

英語名	Cadherin-17	市販薬剤の数	0
治験薬の数	17	ターゲットの別称	Liver-intestine cadherin，HPT-1，Intestinal peptide-associated transporter HPT-1，LI-cadherin，HPT-1 Cadherin，Cadherin 17， LI Cadherin (Liver-Intestine)，HPT1，Human Intestinal Peptide-Associated Transporter HPT-1，LI Cadherin，Cadherin，Cadherin 17，Human Peptide Transporter 1
研究＆開発段階	Phase 2 Clinical

英語名	Cadherin-17
ターゲットの別称	Liver-intestine cadherin，HPT-1，Intestinal peptide-associated transporter HPT-1，LI-cadherin，HPT-1 Cadherin，Cadherin 17， LI Cadherin (Liver-Intestine)，HPT1，Human Intestinal Peptide-Associated Transporter HPT-1，LI Cadherin，Cadherin，Cadherin 17，Human Peptide Transporter 1
市販薬剤の数	0
治験薬の数	17
研究＆開発段階	Phase 2 Clinical

Cadherin-17 製品リスト

属性
Protein (30)Cell (1)
製品ライブラリ
オンライン (31)
種
Mouse (4)Human (22)Rat (1)Cynomolgus (3)Rhesus macaque (1)
タグ
His Tag (11)His Tag & Avi Tag (4)Mouse IgG Fc Tag (1)Fc Tag (12)Fc Tag & Avi Tag (2)- (1)
マーカー
Unconjugated (23)Biotin-labeled (6)- (1)FITC Labeled (1)

製品番号	種	発現システム	製品説明
HOT CA7-H52E6	Human	HEK293	Biotinylated Human Cadherin-17 / CDH17 Protein, His,Avitag™ (MALS verified)
HOT CA7-H52H3	Human	HEK293	Human Cadherin-17 / CDH17 Protein, His Tag
HOT CA7-H52H4	Human	HEK293	Human Cadherin-17 / CDH17 Protein, His Tag, low endotoxin (Active)
HOT CA7-M52H5	Mouse	HEK293	Mouse Cadherin-17 / CDH17 Protein, His Tag (MALS verified)
HOT CA7-C52H3	Cynomolgus	HEK293	Cynomolgus Cadherin-17 / CDH17 Protein, His Tag (MALS verified)
CA7-H5253	Human	HEK293	Human Cadherin-17 / CDH17 Protein, Fc Tag (Active, MALS verified)
CA7-H5254	Human	HEK293	Human Cadherin-17 / CDH17 Protein, Fc Tag
CA7-H5255	Human	HEK293	Human Cadherin-17 / CDH17 (450-566) Protein, Fc Tag (MALS verified)
CA7-H5256	Human	HEK293	Human Cadherin-17 / CDH17 (341-449) Protein, Fc Tag
CA7-H5257	Human	HEK293	Human Cadherin-17 / CDH17 (129-244) Protein, Fc Tag (MALS verified)

総数量31

Cadherin-17バックグランド

Cadherin-17, also known as liver-intestine (LI) Cadherin, belongs to the cadherin family of calcium-dependent cell adhesion molecules. In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach.

Cadherin-17分子の別称

Cadherin-17,CDH17,HPT-1,LI-cadherin

抗体購入プラットフォーム

プロジェクト	ステージ	タイプ	由来	疾患領域	適応症
CDH17 mAb - 01	PCC	Monoclonal	Humanized Mouse	Solid Tumor	Colorectal cancer,Gastric Cancer

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
LM-350	LM-350	Phase 2 Clinical	LaNova Medicines Ltd	Gastrointestinal Neoplasms; Neoplasms; Solid tumours	詳細
7MW-4911	7MW-4911	Phase 2 Clinical	Mabwell (Shanghai) Bioscience Co Ltd	Colorectal Neoplasms; Gastrointestinal Neoplasms; Solid tumours	詳細
CM518D1	CM518D1; CM-518-D-1	Phase 2 Clinical	Keymed Biosciences Co Ltd	Solid tumours	詳細
HS-20110	HS20110; HS-20110	Phase 2 Clinical	Changzhou Hengbang Pharmaceutical Co Ltd, Shanghai Hansoh Biomedical Co Ltd	Carcinoma, Renal Cell; Colorectal Neoplasms; Solid tumours	詳細
AMT-676	AMT-676	Phase 2 Clinical	Multitude Therapeutics Inc	Colorectal Neoplasms; Pancreatic Neoplasms; Solid tumours; Stomach Neoplasms	詳細
CHM-2101	CDH17-CAR T; CHM-2101; CHM2101; CHM-2101 CAR-T cells	Phase 2 Clinical	University Of Pennsylvania	Colorectal Neoplasms; Gastrointestinal Neoplasms; Neuroendocrine Tumors; Pancreatic Neoplasms; Stomach Neoplasms	詳細
MRG-007	MRG-007; ARR-217	Phase 2 Clinical	Lepu Biopharma Co Ltd	Colorectal Neoplasms; Neoplasm Metastasis; Pancreatic Neoplasms; Solid tumours; Stomach Neoplasms	詳細
BI-905711	BI-905711	Phase 1 Clinical	Boehringer Ingelheim International Gmbh	Cholangiocarcinoma; Gastrointestinal Neoplasms; Pancreatic Neoplasms	詳細
Cabotamig	ARB-202	Phase 1 Clinical	Arbele Corp	Biliary Tract Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms; Esophageal adenocarcinoma; Gastrointestinal Neoplasms; Liver Neoplasms; Neuroendocrine Tumors; Pancreatic Neoplasms; Stomach Neoplasms	詳細
HDM-2017	HDM-2017; HDM2017	Phase 1 Clinical	Hangzhou Zhongmei Huadong Pharmaceutical Co Ltd	Colorectal Neoplasms; Solid tumours	詳細
SIM-0609	SIM-0609; SIM0609	Phase 1 Clinical	Shanghai Xianwei Pharmaceutical Technology Co Ltd	Gastrointestinal Neoplasms; Neoplasm Metastasis; Solid tumours	詳細
UCLH-801	UCLH-801	Phase 1 Clinical	UTC Therapeutics Inc	Biliary Tract Neoplasms; Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Neoplasms; Stomach Neoplasms	詳細
Anti-CDH17 CAR-T cells Therapy (Guangzhou Bio-Gene Technology)		Phase 1 Clinical	Guangzhou Bio-Gene Technology Co Ltd	Solid tumours	詳細
Anti-CDH17 CAR-T Cell therapy (UTC Therapeutics)		Phase 1 Clinical	UTC Therapeutics Inc	Solid tumours	詳細
YL-217	YL217; YL-217	Phase 1 Clinical	MediLink Therapeutics Co Ltd	Solid tumours	詳細
TORL-3-600	TORL-3-600	Phase 1 Clinical	Torl Biotherapeutics LLC	Colorectal Neoplasms; Solid tumours	詳細
CDH17 - IHC Test(Arbele)		Clinical	Arbele Corp	Gastrointestinal Neoplasms	詳細