CCL19

CCL19

CCL19 詳細

Molecule Name
C-C motif chemokine 19
分子の別称
CCL19,MIP-3 beta,MIP-3-beta,ELC,MIP3B,SCYA19,EBI1 ligand chemokine
Drug Development Progress
治験薬の数1
市販薬剤の数0
研究&開発段階Phase 1 Clinical
ターゲットの別称
Beta-chemokine exodus-3,CK beta-11,Epstein-Barr virus-induced molecule 1 ligand chemokine,EBI1 ligand chemokine,ELC,Macrophage inflammatory protein 3 beta,MIP-3-beta,Small-inducible cytokine A19,MIP3B,SCYA19
バックグランド
C-C motif chemokine 19(CCL19) is as known as CK beta-11, ELC, MIP3B and SCYA19. May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4.

CCL19 製品リスト

Species
  • Human(1)
Tag
  • Tag Free(1)
Host
  • HEK293(1)
Conjugate
  • Unconjugated(1)
Grade
  • RUO(1)
Low Endotoxin
  • Yes(1)
MoleculeCat. No.Product Name種HostStructurePurityActivitySize&Price
CCL19
Human CCL19 / MIP-3 beta Protein, Tag Free, low endotoxin (HPLC verified)
Human
HEK293
HPLCSDS-PAGE

$360.00

50ug
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治験薬に関する情報

英語名研究コード研究開発ステージ会社適応症臨床試験
Anti-GPC3 chimeric antigen receptor T cell therapy (Hunan Zhaotai Yongren Biotech/Guangdong Zhaotai Invivo Biomedicine)Phase 1 ClinicalGuangdong Zhaotai Invivo Biomedicine Co Ltd, Hunan Zhaotai Yongren Biotech Co Ltd
Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung
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