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CCL2

CCL2 詳細

英語名	C-C motif chemokine 2	市販薬剤の数	1
治験薬の数	3	ターゲットの別称	MCP1，HC11，Monocyte chemotactic protein 1，Monocyte chemoattractant protein 1，CCL2，C-C Motif Chemokine Ligand 2，Monocyte Chemotactic And Activating Factor，Monocyte Secretory Protein JE，Small Inducible Cytokine A2 (Monocyte Chemotactic Protein 1， Homologous To Mouse Sig-Je)，Small Inducible Cytokine Subfamily A (Cys-Cys)， Member 2，Monocyte Chemoattractant Protein-1，Chemokine (C-C Motif) Ligand 2，Small-Inducible Cytokine A2，SCYA2，MCP-1，MCAF，Monocyte Chemotactic Protein 1， Homologous To Mouse Sig-Je，C-C Motif Chemokine 2，HSMCR30，GDCF-2，SMC-CF，Chemokine CCL2，MGC9434
研究＆開発段階	Approved

英語名	C-C motif chemokine 2
ターゲットの別称	MCP1，HC11，Monocyte chemotactic protein 1，Monocyte chemoattractant protein 1，CCL2，C-C Motif Chemokine Ligand 2，Monocyte Chemotactic And Activating Factor，Monocyte Secretory Protein JE，Small Inducible Cytokine A2 (Monocyte Chemotactic Protein 1， Homologous To Mouse Sig-Je)，Small Inducible Cytokine Subfamily A (Cys-Cys)， Member 2，Monocyte Chemoattractant Protein-1，Chemokine (C-C Motif) Ligand 2，Small-Inducible Cytokine A2，SCYA2，MCP-1，MCAF，Monocyte Chemotactic Protein 1， Homologous To Mouse Sig-Je，C-C Motif Chemokine 2，HSMCR30，GDCF-2，SMC-CF，Chemokine CCL2，MGC9434
市販薬剤の数	1
治験薬の数	3
研究＆開発段階	Approved

CCL2 製品リスト

属性
Protein (1)Kits (1)
製品ライブラリ
オンライン (2)
種
Human (2)
タグ
Fc Tag (1)- (1)
マーカー
Unconjugated (1)- (1)

製品番号	種	発現システム	製品説明	タンパク質の構造	純度	特性
CC2-H5255	Human	HEK293	Human CCL2 / MCP-1 Protein, Fc Tag (MALS verified)
CEA-B036	Human	-	Human MCP-1 / CCL2 ELISA Kit

総数量2

CCL2バックグランド

Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. CCL2, a member of the CC subfamily, is characterized by two adjacent cysteine residues. CCL2 displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

CCL2分子の別称

CCL2,C-C motif chemokine 2,MCP-1,MCAF

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
AFX-5931	AFX-5931	Phase 2 Clinical	Afecta Pharmaceuticals Inc	Eczema	詳細
MW-151	MW01-9-034WH; MW-151; MW01-2-151SRM	Phase 1 Clinical	University Of Kentucky	Drug-Related Side Effects and Adverse Reactions; Poisoning	詳細
64CU-DOTA-ECL1i		Phase 1 Clinical	Washington University School Of Medicine	Arteriosclerosis; Carotid Artery Diseases; Heart Diseases	詳細