Select Language

CCL22

CCL22 Overview

English Name	ATP Binding Cassette Subfamily D Member 1	Approved Drugs	1
Drugs in Clinical Trials	2	Target Synonym	ATP Binding Cassette Subfamily D Member 1，Adrenoleukodystrophy Protein，ATP-Binding Cassette Sub-Family D Member 1，ALDP，ATP-Binding Cassette， Sub-Family D (ALD)， Member 1，ABC42，ABCD1，AMN，ALD，ATP Binding Cassette Transporter， Subfamily D， Member 1，Adrenoleukodystrophy
Highest Development Stage	Approved

English Name	ATP Binding Cassette Subfamily D Member 1
Target Synonym	ATP Binding Cassette Subfamily D Member 1，Adrenoleukodystrophy Protein，ATP-Binding Cassette Sub-Family D Member 1，ALDP，ATP-Binding Cassette， Sub-Family D (ALD)， Member 1，ABC42，ABCD1，AMN，ALD，ATP Binding Cassette Transporter， Subfamily D， Member 1，Adrenoleukodystrophy
Approved Drugs	1
Drugs in Clinical Trials	2
Highest Development Stage	Approved

CCL22 Product List

Product Category
Protein (1)
Product Status
Launched (1)
Species
Human (1)
Tag
Fc Tag (1)
Conjugate
Unconjugated (1)

Cat. No.	Species	Host	Product Description	Structure	Purity	Feature
CC2-H5257	Human	HEK293	Human CCL22 / MDC Protein, Fc Tag

Total: 1

CCL22 Background

This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for monocytes, dendritic cells, natural killer cells and for chronically activated T lymphocytes. It also displays a mild activity for primary activated T lymphocytes and has no chemoattractant activity for neutrophils, eosinophils and resting T lymphocytes. The product of this gene binds to chemokine receptor CCR4. This chemokine may play a role in the trafficking of activated T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology.

CCL22 Synonyms

MDC,ABCD-1,SCYA22,STCP-1,DC,B-CK,A-152E5.1

Clinical Drug Information

English Name	Research Code	Highest Development Stage	Company	Indication	Clinical Trial
Pozetaldogene ormesparvovec	SBT-101	Phase 2 Clinical	SwanBio Therapeutics Ltd	Adrenoleukodystrophy	Details
TYF-ABCD1	TYF-ABCD1	Clinical	Shenzhen Geno-Immune Medical Institute	Adrenoleukodystrophy	Details

Marketed Drug Information

English Name	Research Code	Highest Development Stage	Company	Earliest Brand Name	Earliest Approval Country	Earliest Indication	Earliest Approval Company	Earliest Approval Date	Indication	Clinical Trial
Elivaldogene autotemcel		Approved	Genetix Biotherapeutics Inc, Inserm	Lenti-D, Skysona	United States	Adrenoleukodystrophy	Genetix Biotherapeutics Inc	2021-07-27	Adrenoleukodystrophy	Details