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CCL24

CCL24 Overview

English Name	Chemokine (C-C Motif) Ligand 24	Approved Drugs	0
Drugs in Clinical Trials	1	Target Synonym	Small Inducible Cytokine Subfamily A (Cys-Cys)， Member 24，Chemokine (C-C Motif) Ligand 24，Small-Inducible Cytokine A24，MPIF-2，Ckb-6，Chemokine CCL24，MPIF2，SCYA24，Eotaxin-2，CK-beta-6，Myeloid progenitor inhibitory factor 2，C-C motif chemokine 24，CCL24，C-C Motif Chemokine Ligand 24，Eosinophil Chemotactic Protein 2
Highest Development Stage	Phase 2 Clinical

English Name	Chemokine (C-C Motif) Ligand 24
Target Synonym	Small Inducible Cytokine Subfamily A (Cys-Cys)， Member 24，Chemokine (C-C Motif) Ligand 24，Small-Inducible Cytokine A24，MPIF-2，Ckb-6，Chemokine CCL24，MPIF2，SCYA24，Eotaxin-2，CK-beta-6，Myeloid progenitor inhibitory factor 2，C-C motif chemokine 24，CCL24，C-C Motif Chemokine Ligand 24，Eosinophil Chemotactic Protein 2
Approved Drugs	0
Drugs in Clinical Trials	1
Highest Development Stage	Phase 2 Clinical

CCL24 Product List

Product Category
Protein (1)
Product Status
Launched (1)
Species
Human (1)
Tag
His Tag (1)
Conjugate
Unconjugated (1)

Cat. No.	Species	Host	Product Description	Structure	Purity	Feature
CC4-H52H1	Human	HEK293	Human CCL24/Eotaxin-2 Protein, His Tag (HPLC verified)

Total: 1

CCL24 Background

C-C motif chemokine ligand 24 (CCL24), also known as eotaxin2, belongs to CC chemokines like MCP-1, and it mainly chemoattracts eosinophils. CCL24 can promote the separation of eosinophils from endothelial cells and then combine with its sole ligand to promote eosinophils to enter the tissue. CCL24 was not originally found in eosinophils but was first isolated from monocytes. Latest, it was found that the expression of CCL24 in the bronchial epithelial cells of asthma patients increased. CCL24 promotes immune cell trafficking and activation as well as profibrotic activities through the CCR3 receptor (C-C chemokine receptor type 3). Both CCL24 and CCR3 is involved in lung and skin inflammation and fibrosis.

CCL24 Synonyms

C-C motif chemokine 24,CK-beta-6,Eosinophil chemotactic protein 2,Myeloid progenitor inhibitory factor 2,Small-inducible cytokine A24,Eotaxin-2,MPIF-2,SCYA24,MPIF2

Clinical Drug Information

English Name	Research Code	Highest Development Stage	Company	Indication	Clinical Trial
Nebokitug	CM-101	Phase 2 Clinical	Chemomab Therapeutics Ltd	Cholangitis, Sclerosing; Metabolic Dysfunction-Associated Steatotic Liver Disease; Scleroderma, Systemic	Details