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CCL24

CCL24 詳細

英語名	Chemokine (C-C Motif) Ligand 24	市販薬剤の数	0
治験薬の数	1	ターゲットの別称	Small Inducible Cytokine Subfamily A (Cys-Cys)， Member 24，Chemokine (C-C Motif) Ligand 24，Small-Inducible Cytokine A24，MPIF-2，Ckb-6，Chemokine CCL24，MPIF2，SCYA24，Eotaxin-2，CK-beta-6，Myeloid progenitor inhibitory factor 2，C-C motif chemokine 24，CCL24，C-C Motif Chemokine Ligand 24，Eosinophil Chemotactic Protein 2
研究＆開発段階	Phase 2 Clinical

英語名	Chemokine (C-C Motif) Ligand 24
ターゲットの別称	Small Inducible Cytokine Subfamily A (Cys-Cys)， Member 24，Chemokine (C-C Motif) Ligand 24，Small-Inducible Cytokine A24，MPIF-2，Ckb-6，Chemokine CCL24，MPIF2，SCYA24，Eotaxin-2，CK-beta-6，Myeloid progenitor inhibitory factor 2，C-C motif chemokine 24，CCL24，C-C Motif Chemokine Ligand 24，Eosinophil Chemotactic Protein 2
市販薬剤の数	0
治験薬の数	1
研究＆開発段階	Phase 2 Clinical

CCL24 製品リスト

属性
Protein (1)
製品ライブラリ
オンライン (1)
種
Human (1)
タグ
His Tag (1)
マーカー
Unconjugated (1)

製品番号	種	発現システム	製品説明	タンパク質の構造	純度	特性
CC4-H52H1	Human	HEK293	Human CCL24/Eotaxin-2 Protein, His Tag (HPLC verified)

総数量1

CCL24バックグランド

C-C motif chemokine ligand 24 (CCL24), also known as eotaxin2, belongs to CC chemokines like MCP-1, and it mainly chemoattracts eosinophils. CCL24 can promote the separation of eosinophils from endothelial cells and then combine with its sole ligand to promote eosinophils to enter the tissue. CCL24 was not originally found in eosinophils but was first isolated from monocytes. Latest, it was found that the expression of CCL24 in the bronchial epithelial cells of asthma patients increased. CCL24 promotes immune cell trafficking and activation as well as profibrotic activities through the CCR3 receptor (C-C chemokine receptor type 3). Both CCL24 and CCR3 is involved in lung and skin inflammation and fibrosis.

CCL24分子の別称

C-C motif chemokine 24,CK-beta-6,Eosinophil chemotactic protein 2,Myeloid progenitor inhibitory factor 2,Small-inducible cytokine A24,Eotaxin-2,MPIF-2,SCYA24,MPIF2

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Nebokitug	CM-101	Phase 2 Clinical	Chemomab Therapeutics Ltd	Cholangitis, Sclerosing; Metabolic Dysfunction-Associated Steatotic Liver Disease; Scleroderma, Systemic	詳細