言語を選択

CD2

CD2 詳細

英語名	T-cell surface antigen CD2	市販薬剤の数	0
治験薬の数	3	ターゲットの別称	T11，T-Cell Surface Antigen CD2，LFA-2，CD2 Antigens，CD2，LFA-3 Receptor，CD2 Molecule，Rosette Receptor，SRBC，CD2 Antigen，CD2 Antigen (P50)， Sheep Red Blood Cell Receptor，T-Cell Surface Antigen T11/Leu-5，Lymphocyte-Function Antigen-2，Erythrocyte Receptor
研究＆開発段階	Phase 2 Clinical

英語名	T-cell surface antigen CD2
ターゲットの別称	T11，T-Cell Surface Antigen CD2，LFA-2，CD2 Antigens，CD2，LFA-3 Receptor，CD2 Molecule，Rosette Receptor，SRBC，CD2 Antigen，CD2 Antigen (P50)， Sheep Red Blood Cell Receptor，T-Cell Surface Antigen T11/Leu-5，Lymphocyte-Function Antigen-2，Erythrocyte Receptor
市販薬剤の数	0
治験薬の数	3
研究＆開発段階	Phase 2 Clinical

CD2 製品リスト

属性
Protein (6)Antibody (6)
製品ライブラリ
オンライン (12)
種
Human (6)Cynomolgus (2)Rabbit (1)Mouse (3)
タグ
His Tag (3)Fc Tag (1)His Tag & Avi Tag (2)- (6)
マーカー
Unconjugated (7)Biotin-labeled (2)PE Labeled (1)APC Labeled (2)

製品番号	種	発現システム	製品説明
HOT CD2-H5226	Human	HEK293	Human CD2 / SRBC Protein, His Tag, low endotoxin (MALS verified)
HOT CD2-H5258	Human	HEK293	Human CD2 / SRBC Protein, Fc Tag, low endotoxin (MALS verified)
HOT CD2-H82E6	Human	HEK293	Biotinylated Human CD2 / SRBC Protein, His,Avitag™ (MALS verified)
HOT CD2-C52H5	Cynomolgus	HEK293	Cynomolgus CD2 / SRBC Protein, His Tag, low endotoxin (MALS verified)
CD2-AHF48G1	Human	HEK293	APC-Labeled Monoclonal Anti-Human CD2 Antibody, Mouse IgG1 (RPA-2.10) (0.03% Proclin)
CD2-C238G1	Human	HEK293	Monoclonal Anti-Human CD2 Antibody, Mouse IgG1 (RPA-2.10), premium grade
CD2-C238GN	Human	HEK293	Monoclonal Anti-Human CD2 Antibody, Mouse IgG1 (RPA-2.10), Research Grade
CD2-AHFM8	Mouse	HEK293	APC-Labeled Monoclonal Anti-Human CD2 Antibody, Mouse IgG1 (RPA-2.10) (0.03% Proclin)
CD2-M52H3	Mouse	HEK293	Mouse CD2 / SRBC Protein, His Tag (MALS verified)
CD2-PCFM8	Mouse	HEK293	PE-Labeled Monoclonal Anti-Human CD2 Antibody, Mouse IgG1 (RPA-2.10) (0.03% Proclin)

総数量12

CD2バックグランド

T-cell surface antigen CD2 is also known as Erythrocyte receptor, LFA-2, LFA-3 receptor, Rosette receptor, T-cell surface antigen T11/Leu-5 and SRBC, is a single-pass type I membrane protein found on the surface of T cells and natural killer (NK) cells. CD2 is a member of the immunoglobulin superfamily. CD2 / SRBC contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain. CD2 / SRBC interacts with other adhesion molecules, such as lymphocyte function-associated antigen-3 (LFA-3 / CD58) in humans, or CD48 in rodents, which are expressed on the surfaces of other cells. In addition to its adhesive properties, CD2 also acts as a co-stimulatory molecule on T and NK cells. CD2 is a specific marker for T cells and NK cells, and can therefore be used in immunohistochemistry to identify the presence of such cells in tissue sections.

CD2分子の別称

CD2,SRBC,LFA-2,T11

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Siplizumab	MEDI-507; TCD-601	Phase 2 Clinical	Catholic University Of Louvain, Itb-Med Llc	Amyotrophic Lateral Sclerosis; Anemia, Sickle Cell; Cholangitis, Sclerosing; Diabetes Mellitus, Type 1; End Stage Liver Disease; Graft vs Host Disease; Hepatitis, Autoimmune; Hidradenitis Suppurativa; Kidney Diseases; Kidney Failure, Chronic; Leukemia; Liver Cirrhosis; Liver Diseases; Lymphoma; Lymphoma, Extranodal NK-T-Cell; Lymphoma, T-Cell; Multiple Myeloma; Myelodysplastic Syndromes; Neoplasms; Plaque psoriasis; Psoriasis; Rejection of renal transplantation; Rejection of liver transplantation; Renal Insufficiency	詳細
SBT-11-5301	SBT115301	Phase 1 Clinical	Sonoma Biotherapeutics Inc	Autoimmune Diseases	詳細
PIT-565	PIT-565	Phase 1 Clinical	Novartis Pharma Ag	Arthritis, Rheumatoid; Lupus Erythematosus, Systemic; Lymphoma, B-Cell; Neoplasms; Nephrosis; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	詳細