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CD300a

CD300a Overview

English Name	CMRF35-like molecule 8	Approved Drugs	0
Drugs in Clinical Trials	0	Target Synonym	CLM-8，CD300 antigen-like family member A，CMRF-35-H9 (CMRF35-H9)，CMRF35-H，IRC1/IRC2，Immunoglobulin superfamily member 12 (IgSF12)，Inhibitory receptor protein 60 (IRp60)，NK inhibitory receptor
Highest Development Stage	Preclinical

English Name	CMRF35-like molecule 8
Target Synonym	CLM-8，CD300 antigen-like family member A，CMRF-35-H9 (CMRF35-H9)，CMRF35-H，IRC1/IRC2，Immunoglobulin superfamily member 12 (IgSF12)，Inhibitory receptor protein 60 (IRp60)，NK inhibitory receptor
Approved Drugs	0
Drugs in Clinical Trials	0
Highest Development Stage	Preclinical

CD300a Product List

Product Category
Protein (1)
Product Status
Launched (1)
Species
Human (1)
Tag
His Tag (1)
Conjugate
Unconjugated (1)

Cat. No.	Species	Host	Product Description	Structure	Purity	Feature
CDA-H52H5	Human	HEK293	Human CD300a / LMIR1 Protein, His Tag, low endotoxin (MALS verified)

Total: 1

CD300a Background

CD300a, expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes. Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation. Negatively regulates the Toll-like receptor (TLR) signaling mediated by MYD88 but not TRIF through activation of PTPN6.