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CD44

CD44 詳細

英語名	CD44 antigen	市販薬剤の数	0
治験薬の数	10	ターゲットの別称	Hermes Antigen，Hyaluronate Receptor，Cell Surface Glycoprotein CD44，MC56，PGP-1，CD44，CDW44，GP90 Lymphocyte Homing/Adhesion Receptor，MIC4，LHR，Hematopoietic Cell E- And L-Selectin Ligand，CD44 Antigen (Homing Function And Indian Blood Group System)，MDU3，Extracellular Matrix Receptor III，Heparan Sulfate Proteoglycan，HUTCH-I，ECMR-III，Epican，Chondroitin Sulfate Proteoglycan 8，Soluble CD44，MDU2，Pgp1，CSPG8，HCELL，Phagocytic Glycoprotein 1，Indian Blood Group Antigen，IN，Phagocytic Glycoprotein I，CD44 Molecule (Indian Blood Group)，CD44 Antigen，PGP-I，Homing Function And Indian Blood Group System，Hyaluronan Receptors，CD44R
研究＆開発段階	Phase 3 Clinical

英語名	CD44 antigen
ターゲットの別称	Hermes Antigen，Hyaluronate Receptor，Cell Surface Glycoprotein CD44，MC56，PGP-1，CD44，CDW44，GP90 Lymphocyte Homing/Adhesion Receptor，MIC4，LHR，Hematopoietic Cell E- And L-Selectin Ligand，CD44 Antigen (Homing Function And Indian Blood Group System)，MDU3，Extracellular Matrix Receptor III，Heparan Sulfate Proteoglycan，HUTCH-I，ECMR-III，Epican，Chondroitin Sulfate Proteoglycan 8，Soluble CD44，MDU2，Pgp1，CSPG8，HCELL，Phagocytic Glycoprotein 1，Indian Blood Group Antigen，IN，Phagocytic Glycoprotein I，CD44 Molecule (Indian Blood Group)，CD44 Antigen，PGP-I，Homing Function And Indian Blood Group System，Hyaluronan Receptors，CD44R
市販薬剤の数	0
治験薬の数	10
研究＆開発段階	Phase 3 Clinical

CD44 製品リスト

属性
Protein (2)Antibody (2)
製品ライブラリ
オンライン (4)
種
Human (2)Rabbit (1)Mouse (1)
タグ
His Tag (1)Fc Tag (1)- (2)
マーカー
Unconjugated (3)PE Labeled (1)

製品番号	種	発現システム	製品説明
CD4-H5226	Human	HEK293	Human CD44 Protein, His Tag
PG1-H5255	Human	HEK293	Human CD44 Protein, Fc Tag (HPLC-verified)
FABm039-01	Mouse	-	PE-Labeled Monoclonal Anti-Human CD44 Antibody, Mouse IgG1 (AS625) (0.03% Proclin)
HGS-S246	Rabbit	-	Recombinant Monoclonal Anti-CD44 Antibody, Rabbit (5G3)

総数量4

CD44バックグランド

CD44 antigen is a cell-surface glycoprotein involved in cell–cell interactions, cell adhesion and migration. CD44 is expressed in a large number of mammalian cell types. CD44 is a receptor for hyaluronic acid and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). CD44 function is controlled by its posttranslational modifications. One critical modification involves discrete sialofucosylations rendering the selectin-binding glycoform of CD44 called HCELL (for Hematopoietic Cell E-selectin/L-selectin Ligand). CD44 participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms.

CD44分子の別称

CD44,CDW44,CSPG8,ECMR-III,HCELL,HUTCH-I,IN,LHR,MC56,MDU2,MDU3,MIC4,Pgp1,Epican

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Paclitaxel/Hyaluronic acid		Phase 3 Clinical	Fidia Pharma	Carcinoma, Papillary; Urinary Bladder Neoplasms	詳細
CA-102N	CA-102N	Phase 2 Clinical	Holy Stone Healthcare Co Ltd	Colorectal Neoplasms; Solid tumours	詳細
P-134	P-134; P134	Phase 2 Clinical	Tianjin Tasly Pharmaceutical Co Ltd	Glioblastoma	詳細
Rosuvastatin liposome encapsulated therapy (Beijing Inno Medicine)	YN001; YN-001	Phase 2 Clinical	Beijing Inno Medicine Co Ltd	Atherosclerosis; Cardiovascular Diseases; Cerebrovascular Disorders; Coronary Artery Disease; Erectile Dysfunction	詳細
AMT-116(Multitude Therapeutics)	AMT-116; AMT-116-ADC	Phase 2 Clinical	Multitude Therapeutics Inc	Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Head and Neck Neoplasms; Solid tumours	詳細
Hyaluronic acid/Fluorouracil	HA-5FU; HA-5-fluorouracil; Hyaluronic acid-5-fluorouracil complex; Hyaluronan acid-5-fluorouracil complex	Phase 2 Clinical	Alchemia Ltd, Monash University	Colorectal Neoplasms	詳細
AMC-303	AMC-303; HP-558	Phase 1 Clinical	Amcure Gmbh	Esophageal Squamous Cell Carcinoma; Solid tumours	詳細
Clodronic acid/Hyaluronic acid		Phase 1 Clinical	Abiogen Pharma Spa	Osteoarthritis	詳細
177Lu-AKIR001	177Lu-AKIR001	Phase 1 Clinical	Akiram Therapeutics AB	Carcinoma, Non-Small-Cell Lung; Head and Neck Neoplasms; Neoplasms; Thyroid Carcinoma, Anaplastic; Uterine Cervical Neoplasms; Vulvar Neoplasms	詳細
BGC-0228	BGC-0228	Phase 1 Clinical	Brightgene Bio-Medical Technology Co Ltd	Solid tumours	詳細