言語を選択

CD5

CD5 詳細

英語名	T-cell surface glycoprotein CD5	市販薬剤の数	0
治験薬の数	13	ターゲットの別称	Epididymis Secretory Sperm Binding Protein，CD5，Lymphocyte antigen T1/Leu-1，T-cell surface glycoprotein CD5，CD5 Molecule，CD5 Antigen (P56-62)，LEU1，CD5 Antigen，T1，CD5 Antigens
研究＆開発段階	Phase 2 Clinical

英語名	T-cell surface glycoprotein CD5
ターゲットの別称	Epididymis Secretory Sperm Binding Protein，CD5，Lymphocyte antigen T1/Leu-1，T-cell surface glycoprotein CD5，CD5 Molecule，CD5 Antigen (P56-62)，LEU1，CD5 Antigen，T1，CD5 Antigens
市販薬剤の数	0
治験薬の数	13
研究＆開発段階	Phase 2 Clinical

CD5 製品リスト

属性
Protein (17)Antibody (2)Kits (1)Cell (1)
製品ライブラリ
オンライン (21)
種
Human (14)Mouse (3)Rhesus macaque (3)Rabbit (1)
タグ
His Tag (7)His Tag & Avi Tag (4)Fc Tag & Avi Tag (2)Fc Tag (4)- (4)
マーカー
Unconjugated (6)FITC Labeled (2)Biotin-labeled (6)PE Labeled (2)AF647 Labeled (1)AF488 Labeled (2)- (2)

製品番号	種	発現システム	製品説明
HOT CD5-H52H5	Human	HEK293	Human CD5 Protein, His Tag, low endotoxin
HOT CD5-H82E5	Human	HEK293	Biotinylated Human CD5 Protein, His,Avitag™, premium grade
HOT CD5-HP2H6	Human	HEK293	PE-Labeled Human CD5 Protein, His Tag (Site-specific conjugation)
HOT GMP-CD5H24	Human	HEK293	GMP Biotinylated Human CD5 Protein, His,Avitag™
HOT CD5-M82E3	Mouse	HEK293	Biotinylated Mouse CD5 Protein, His,Avitag™ (MALS verified)
HOT CD5-R52H3	Rhesus macaque	HEK293	Rhesus macaque CD5 Protein, His Tag (MALS verified)
CD5-H5253	Human	HEK293	Human CD5 Protein, Fc Tag, low endotoxin (MALS verified)
CD5-H5255	Human	HEK293	Human CD5 Protein, Fc Tag (MALS verified)
CD5-H52H2	Human	HEK293	FITC-Labeled Human CD5 Protein, His Tag
CD5-H82F3	Human	HEK293	Biotinylated Human CD5 Protein, Fc,Avitag™ (MALS verified)

総数量21

CD5バックグランド

T-cell surface glycoprotein CD5 is also known as Lymphocyte antigen T1/Leu-1 and LEU1,which is phosphorylated on tyrosine residues by LYN,so CD5 can create binding sites for PTPN6/SHP-1.CD5 may act as a receptor in regulating T-cell proliferation. CD5 is expressed at various developmental and activation stages on human B cells.CD5 is a well established negative regulator of TCR and BCR signalling.CD5-positive cells may also prevent the emergence of autoimmunity by provision of cytokines such as IL-10. Development,selection and function of different B- and T-cell subsets or their preferential survival may be directly or indirectly dependent on different glycan structures associated with CD5 or CD5-like molecules.

CD5分子の別称

CD5,LEU1

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
CD5-targeted CAR-T cells therapy(Senlang Biotechnology)		Phase 2 Clinical	Hebei Senlang Biological Technology Co Ltd	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	詳細
CD5/CD7-Specific CAR-T Cells therapy(Essen Biotech)	BAH246; BAH-246; EB-BH2026	Phase 2 Clinical	Essen Biotech	Central Nervous System Diseases; Leukemia, Prolymphocytic, T-Cell; Leukemia, T-Cell; Lymphoma, T-Cell; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	詳細
CD5 CAR T Cells therapy(Beijing GoBroad Hospital)		Phase 2 Clinical	Beijing GoBroad Hospital	Lymphoma, T-Cell; Lymphoma, T-Cell, Cutaneous; Lymphoma, T-Cell, Peripheral; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	詳細
MB-105(March Biosciences)	MB-105(March Biosciences)	Phase 2 Clinical	March Biosciences Inc	Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Mantle-Cell; Lymphoma, T-Cell; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	詳細
anti-CD5 CAR T-cell therapy (Beijing Boren Hospital)		Phase 1 Clinical	Beijing Gao Boren Hospital Co Ltd	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	詳細
CD5CAR	CD5CAR	Phase 1 Clinical	iCell Gene Therapeutics LLC	Lymphoma, Non-Hodgkin; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	詳細
CT-125A	CT-125A; RD-125	Phase 1 Clinical	Nanjing Iaso Biotherapeutics Co Ltd	Hematologic Neoplasms; Leukemia, Lymphocytic, Chronic, B-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Lymphoma, T-Cell; Lymphoma, T-Cell, Peripheral; Plasmablastic Lymphoma; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	詳細
CD5 Targeting Chimeric Antigen Receptor NK Cells (CAR-NK) thrapy(Precision Biotechnology)		Phase 1 Clinical	Chongqing Precision Biotechnology Co Ltd	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	詳細
CD5 CAR T-cells therapy(Yake Biotechnology)		Phase 1 Clinical	Shanghai YaKe Biotechnology Co Ltd	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	詳細
AB-205 (Artiva Biotherapeutics/GC Cell)	CD5 CAR-NK; GCC-2005; GL-205; GCC2005	Phase 1 Clinical	GC Cell Corp	Lymphoma, T-Cell	詳細
Autologous CAR-T cell therapy(Vittoria Biotherapeutics)	VIPER-101; Senza5 CART5; VIPER101	Phase 1 Clinical	Vittoria Biotherapeutics Inc	Lymphoma, T-Cell	詳細
CD5 CAR T-Cells (Baylor College of Medicine)		Phase 1 Clinical	Baylor College Of Medicine	Lymphoma, Non-Hodgkin; Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	詳細
CD5 CAR-T Therapy(Xuanwu Hospital)		Phase 1 Clinical	Xuanwu Hospital Of Capital Medical University	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma	詳細