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CD73

CD73 詳細

英語名	5'-nucleotidase	市販薬剤の数	0
治験薬の数	36	ターゲットの別称	5' Nucleotidase (CD73)，5'-nucleotidase，5'-Nucleotidase， Ecto (CD73)，Ecto-5'-nucleotidase，NT5E，5'-Nucleotidase Ecto，Ecto-5-Nucleotidase，5-NT，Purine 5-Prime-Nucleotidase，5-Nucleotidase， Ecto (CD73)，5 Nucleotidase (CD73)，5-Nucleotidase Ecto，5-Nucleotidase，CD73 Antigen，EC 3.1.3.5，CALJA，E5NT，ENT，NT，EN，CD73，5'-NT，NT5，NTE，EC:3.1.3.5
研究＆開発段階	Phase 3 Clinical

英語名	5'-nucleotidase
ターゲットの別称	5' Nucleotidase (CD73)，5'-nucleotidase，5'-Nucleotidase， Ecto (CD73)，Ecto-5'-nucleotidase，NT5E，5'-Nucleotidase Ecto，Ecto-5-Nucleotidase，5-NT，Purine 5-Prime-Nucleotidase，5-Nucleotidase， Ecto (CD73)，5 Nucleotidase (CD73)，5-Nucleotidase Ecto，5-Nucleotidase，CD73 Antigen，EC 3.1.3.5，CALJA，E5NT，ENT，NT，EN，CD73，5'-NT，NT5，NTE，EC:3.1.3.5
市販薬剤の数	0
治験薬の数	36
研究＆開発段階	Phase 3 Clinical

CD73 製品リスト

属性
Protein (8)Antibody (2)
製品ライブラリ
オンライン (10)
種
Human (3)Mouse (3)Cynomolgus (1)Canine (1)Rabbit (1)Rat (1)
タグ
His Tag (6)His Tag & Avi Tag (1)Mouse IgG Fc Tag (1)- (2)
マーカー
Unconjugated (7)Biotin-labeled (1)PE Labeled (1)APC Labeled (1)

製品番号	種	発現システム	製品説明
HOT CD3-H52H7	Human	HEK293	Human CD73 / NT5E Protein, His Tag (HPLC-verified) (active enzyme)
HOT CD3-H82E3	Human	HEK293	Biotinylated Human CD73 / NT5E Protein, His,Avitag™
HOT CD3-M52H9	Mouse	HEK293	Mouse CD73 / NT5E Protein, His Tag (active enzyme)
CD3-H5252	Human	HEK293	Human CD73 Protein, Mouse IgG2a Fc Tag (active enzyme)
FABm024-01	Mouse	Hybridoma	PE-Labeled Monoclonal Anti-Human CD73 Antibody, Mouse IgG1 (5A10) (0.03% Proclin)
FABm024-02	Mouse	Hybridoma	APC-Labeled Monoclonal Anti-Human CD73 Antibody, Mouse IgG1 (5A10) (0.03% Proclin)
CD3-C52H5	Canine	HEK293	Canine CD73 / NT5E Protein, His Tag (MALS verified) (active enzyme)
CD3-C52H9	Cynomolgus	HEK293	Cynomolgus CD73 Protein, His Tag (active enzyme)
CD3-R52H3	Rabbit	HEK293	Rabbit CD73 / NT5E Protein, His Tag (active enzyme)
CD3-R52H5	Rat	HEK293	Rat CD73 Protein, His Tag (active enzyme)

総数量10

CD73分子の別称

CD73,NT5E,5'-Nucleotidase,5'-NT,NT5,NTE

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Uliledlimab	TJD-5; TJ-004309; TJ-4309	Phase 3 Clinical	I-Mab Biopharma Co Ltd	Carcinoma, Non-Small-Cell Lung; Carcinoma, Ovarian Epithelial; Gastrointestinal Neoplasms; Head and Neck Neoplasms; Neoplasm Metastasis; Ovarian Neoplasms; Solid tumours; Triple Negative Breast Neoplasms	詳細
Quemliclustat	AB-680	Phase 3 Clinical	Arcus Biosciences Inc	Adenocarcinoma; Bile Duct Neoplasms; Biliary Tract Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Cholangiocarcinoma; Colorectal Neoplasms; Hormone-Resistant Prostate Neoplasms; Pancreatic Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant	詳細
Oleclumab	MEDI-9447	Phase 3 Clinical	Medimmune Llc	Adenocarcinoma; Carcinoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Ovarian Epithelial; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Colorectal Neoplasms; Fallopian Tube Neoplasms; Hemangiosarcoma; Liposarcoma; Osteosarcoma; Ovarian Neoplasms; Pancreatic Neoplasms; Peritoneal Neoplasms; Prostatic Neoplasms; Prostatic Neoplasms, Castration-Resistant; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms	詳細
Dalutrafusp alfa	GS-1423; AGEN-1423	Phase 2 Clinical	Agenus Inc	Carcinoma, Pancreatic Ductal; Colorectal Neoplasms; Liver Neoplasms; Pancreatic Neoplasms; Solid tumours	詳細
BMS-986179	BMS-986179	Phase 2 Clinical	Bristol-Myers Squibb Company	Solid tumours	詳細
Mupadolimab	CPX-006; COR-004 (Corvus Pharmaceuticals); CPI-006	Phase 2 Clinical	Corvus Pharmaceuticals Inc	Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Colorectal Neoplasms; Coronavirus Disease 2019 (COVID-19); Endometrial Neoplasms; Head and Neck Neoplasms; Lymphoma, Non-Hodgkin; Ovarian Neoplasms; Pancreatic Neoplasms; Papillomavirus Infections; Prostatic Neoplasms, Castration-Resistant; Sarcoma; Solid tumours; Squamous Cell Carcinoma of Head and Neck; Triple Negative Breast Neoplasms; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms	詳細
XW-LTH-03	XW-LTH-03	Phase 2 Clinical	Shanghai SinoBay Biotechnology Co Ltd	Stomach Neoplasms	詳細
CD73/AXL.HypoSti.CAR-T cells therapy (Pla General Hospital)		Phase 2 Clinical	Pla General Hospital	Solid tumours	詳細
Dresbuxelimab	AK-119	Phase 2 Clinical		Carcinoma, Non-Small-Cell Lung; Colorectal Neoplasms; Coronavirus Disease 2019 (COVID-19); Idiopathic Pulmonary Fibrosis; Solid tumours	詳細
GI-108	GI-108	Phase 2 Clinical	GI Innovation Inc	Carcinoma, Non-Small-Cell Lung; Carcinoma, Renal Cell; Neoplasms; Pancreatic Neoplasms; Solid tumours; Squamous Cell Carcinoma of Head and Neck	詳細
S-095024	S-095024; S095024	Phase 2 Clinical	Institut De Recherches Internationales Servier, Regeneron Pharmaceuticals Inc, Servier Bio-Innovation LLC	Carcinoma, Non-Small-Cell Lung	詳細
HB-0052	HB0052; HB-0052	Phase 2 Clinical	Shanghai Huaota Biopharmaceutical Co Ltd, Zhejiang Huahai Pharmaceutical Co Ltd	Pancreatic Neoplasms; Solid tumours	詳細
HB-0045	HB-0045; HB0045	Phase 2 Clinical	HuaBo Biopharm Co Ltd, Shanghai Huaota Biopharmaceutical Co Ltd	Solid tumours	詳細
JAB-BX102	JAB-BX102	Phase 2 Clinical	Jacobio Pharmaceuticals Co Ltd	Solid tumours	詳細
PT-199	PT-199	Phase 2 Clinical	Phanes Therapeutics Inc	Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Solid tumours	詳細
LY-3475070	LY-3475070	Phase 1 Clinical	Eli Lilly And Company	Neoplasms	詳細
Anti-CD73 monoclonal antibody (Bristol-Myers Squibb)		Phase 1 Clinical	Bristol-Myers Squibb Company	Neoplasms	詳細
AP-601	AP-601	Phase 1 Clinical	AP Biosciences Inc	Neoplasms; Solid tumours	詳細
68Ga-dPNE	68Ga-dPNE	Phase 1 Clinical	First Affiliated Hospital Of Fujian Medical University	Neoplasms	詳細
AK-137	AK137; AK-137	Phase 1 Clinical		Neoplasms	詳細
68GA-DOTA-dPNE	68GA-DOTA-dPNE	Phase 1 Clinical	Peking Union Medical College Hospital	Breast Neoplasms	詳細
LNF-2008	LNF-2008; LNF2008	Phase 1 Clinical	Shandong New Time Pharmaceutical Co Ltd	Solid tumours	詳細
HB-0046	HB0046; HB-0046	Phase 1 Clinical	HuaBo Biopharm Co Ltd, Shanghai Huaota Biopharmaceutical Co Ltd	Solid tumours	詳細
SYS-6011	SYS6011; SYS-6011	Phase 1 Clinical	Jushi Biopharmaceutical Co Ltd	Solid tumours	詳細
BPI-472372	BPI-472372	Phase 1 Clinical	Betta Pharmaceuticals Co Ltd	Solid tumours	詳細
BB-1709	BB-1709	Phase 1 Clinical	Bliss Biopharmaceutical (Hangzhou) Co Ltd	Solid tumours	詳細
PM-1015	PM1015; PM-1015	Phase 1 Clinical		Solid tumours	詳細
AK-131	AK-131	Phase 1 Clinical		Neoplasms; Solid tumours	詳細
IBI-325	IBI-325	Phase 1 Clinical		Solid tumours	詳細
BR-101	BR101; BR-101	Phase 1 Clinical	Zhejiang BioRay Biopharmaceuticals Co Ltd	Solid tumours	詳細
CB-708	ATG-037; ATN-037; CB-708; CB708	Phase 1 Clinical	Calithera Biosciences Inc	Carcinoma, Non-Small-Cell Lung; Melanoma; Neoplasms; Solid tumours	詳細
HLX-23	HLX-23	Phase 1 Clinical		Lymphoma; Solid tumours	詳細
ORIC533	ORIC-533	Phase 1 Clinical	Oric Pharmaceuticals Inc	Multiple Myeloma; Neoplasm Metastasis	詳細
IPH-5301	IPH-5301	Phase 1 Clinical	Innate Pharma	Breast Neoplasms; Endometrial Neoplasms; Esophageal Neoplasms; Lung Neoplasms; Metastatic breast cancer; Neoplasm Metastasis; Neoplasms; Pancreatic Neoplasms; Solid tumours; Stomach Neoplasms	詳細
HBM-1007	HBM1007; R 1007; HBM 1007; HBM-1007	Phase 1 Clinical	Harbour Biomed	Neoplasms; Solid tumours	詳細
ABSK-051	ABSK051	Phase 1 Clinical	ABbisko Therapeutics Co Ltd	Neoplasms; Solid tumours	詳細

レビュー

H***g2021-11-29
0評価
Mouse CD73 / NT5E Protein, His Tag (active enzyme)
It was used in research of investgational new drugs. Specifically, I have used this product in my Epitope binning experiments (using Octet) and I am truely satisfied with the results. With this experiment and your product, we have found a approximate epitope binding site. Thanks for your highly qualified product.