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CD8 alpha & beta

CD8 alpha & beta 詳細

英語名	T-cell surface glycoprotein CD8 beta chain	市販薬剤の数	0
治験薬の数	0	ターゲットの別称	CD8b，CD8b Molecule
研究＆開発段階	Preclinical

英語名	T-cell surface glycoprotein CD8 beta chain
ターゲットの別称	CD8b，CD8b Molecule
市販薬剤の数	0
治験薬の数	0
研究＆開発段階	Preclinical

CD8 alpha & beta 製品リスト

属性
Protein (7)
製品ライブラリ
オンライン (7)
種
Human (4)Cynomolgus (2)Mouse (1)
タグ
His Tag (4)His Tag & Avi Tag (2)Fc Tag (1)
マーカー
FITC Labeled (1)Unconjugated (4)Biotin-labeled (2)

製品番号	種	発現システム	製品説明
HOT CDA-H52W5	Human	HEK293	Human CD8 alpha&beta (CD8A&CD8B) Heterodimer Protein, His Tag&Tag Free, low endotoxin (MALS verified)
HOT CDA-H82W7	Human	HEK293	Biotinylated Human CD8 alpha&beta (CD8A&CD8B) Heterodimer Protein, His,Avitag™&Tag Free (MALS verified)
HOT CDA-C52W3	Cynomolgus	HEK293	Cynomolgus CD8 alpha&beta (CD8A&CD8B) Heterodimer Protein, His Tag&Tag Free (MALS verified)
CDA-H5253	Human	HEK293	Human CD8 alpha&beta (CD8A&CD8B) Heterodimer Protein, Fc Tag&Fc Tag, low endotoxin (MALS verified)
CDA-HF2W4	Human	HEK293	FITC-Labeled Human CD8 alpha&beta (CD8A&CD8B) Heterodimer Protein, His Tag&Tag Free
CDA-M52W3	Mouse	HEK293	Mouse CD8 alpha&beta (CD8A&CD8B) Heterodimer Protein, His Tag&Tag Free (MALS verified)
CDA-C82W3	Cynomolgus	HEK293	Biotinylated Cynomolgus CD8 alpha&beta (CD8A&CD8B) Heterodimer Protein, His,Avitag™&Tag Free (MALS verified)

総数量7

CD8 alpha & betaバックグランド

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. CD8A forms disulfide-linked heterodimers with CD8B at the cell surface. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells. Additionally, CD8B plays a critical role in thymic selection of CD8+ T-cells. A palmitoylation site in the cytoplasmic tail of CD8B chain contributes to partitioning of CD8 into the plasma membrane lipid rafts where signaling proteins are enriched.