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CLEC4C

CLEC4C 詳細

英語名	C-Type lectin domain family 4 member C	市販薬剤の数	0
治験薬の数	9	ターゲットの別称	DLEC，HECL，C-type lectin superfamily member 7，CLEC4C，BDCA2，UNQ9361/PRO34150，C-type lectin domain family 4 member C，Dendritic lectin，C-Type (Calcium Dependent， Carbohydrate-Recognition Domain) Lectin， Superfamily Member 7，C-Type Lectin Domain Family 4， Member C，CLECSF11，CLECSF7，BDCA-2，C-Type (Calcium Dependent， Carbohydrate-Recognition Domain) Lectin， Superfamily Member 11，Blood Dendritic Cell Antigen 2 Protein，Blood Dendritic Cell Antigen 2，Dendritic Cell Lectin B，CD303 Antigen，PRO34150，CD303
研究＆開発段階	Phase 3 Clinical

英語名	C-Type lectin domain family 4 member C
ターゲットの別称	DLEC，HECL，C-type lectin superfamily member 7，CLEC4C，BDCA2，UNQ9361/PRO34150，C-type lectin domain family 4 member C，Dendritic lectin，C-Type (Calcium Dependent， Carbohydrate-Recognition Domain) Lectin， Superfamily Member 7，C-Type Lectin Domain Family 4， Member C，CLECSF11，CLECSF7，BDCA-2，C-Type (Calcium Dependent， Carbohydrate-Recognition Domain) Lectin， Superfamily Member 11，Blood Dendritic Cell Antigen 2 Protein，Blood Dendritic Cell Antigen 2，Dendritic Cell Lectin B，CD303 Antigen，PRO34150，CD303
市販薬剤の数	0
治験薬の数	9
研究＆開発段階	Phase 3 Clinical

CLEC4C 製品リスト

属性
Protein (6)
製品ライブラリ
オンライン (6)
種
Human (3)Cynomolgus (3)
タグ
Fc Tag (2)His Tag (2)His Tag & Avi Tag (2)
マーカー
Unconjugated (4)Biotin-labeled (2)

製品番号	種	発現システム	製品説明
HOT CLC-H5245	Human	HEK293	Human CLEC4C / BDCA2 Protein, His Tag
CLC-H5254	Human	HEK293	Human CLEC4C / BDCA2 Protein, Fc Tag
CLC-H82Q3	Human	HEK293	Biotinylated Human CLEC4C / BDCA2 Protein, Avitag™,His Tag
CLC-C5253	Cynomolgus	HEK293	Cynomolgus CLEC4C / BDCA2 Protein, Fc Tag (MALS verified)
CLC-C52H4	Cynomolgus	HEK293	Cynomolgus CLEC4C / BDCA2 Protein, His Tag (MALS verified)
CLC-C82Q3	Cynomolgus	HEK293	Biotinylated Cynomolgus CLEC4C / BDCA2 Protein, Avitag™,His Tag

総数量6

CLEC4Cバックグランド

CLEC4C (C-type lectin domain family 4 member C), also known as BDCA2, CLECSF11, CLECSF7, DLEC and CD303. Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cell. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.

CLEC4C分子の別称

DLEC,CLEC4C,BDCA-2,CD303,CLECSF11,CLECSF7, HECL

治験薬に関する情報

英語名	研究コード	研究開発ステージ	会社	適応症	臨床試験
Litifilimab	BIIB-059	Phase 3 Clinical	Biogen Inc	Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic	詳細
SSGJ-626	SSGJ-626; 626	Phase 2 Clinical	Sunshine GuoJian Pharmaceutical (Shanghai) Co Ltd	Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic	詳細
DB-2304	DB-2304	Phase 2 Clinical	Duality Biologics (Suzhou) Co Ltd	Autoimmune Diseases; Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic	詳細
ANB-101	CBS-004; ANB101	Phase 1 Clinical	Capella Bioscience Ltd	Inflammation; Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic; Scleroderma, Systemic	詳細
BCD-256	BCD-256	Phase 1 Clinical	BIOCAD JSC	Lupus Erythematosus, Systemic	詳細
GB-19	GB-19; GB19	Phase 1 Clinical	Shandong Kexing Bio-Products Co Ltd	Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic	詳細
Recombinant anti-BDCA2 humanized monoclonal antibody (Sansheng Guojian)		Phase 1 Clinical	Sunshine GuoJian Pharmaceutical (Shanghai) Co Ltd	Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic	詳細
HC-022	HC-022; HC022	Phase 1 Clinical	Shanghai Hongcheng Pharmaceutical Co Ltd	Lupus Erythematosus, Cutaneous; Lupus Erythematosus, Systemic	詳細
LBL-047	DNTH-212; LBL-047; DNTH212	Phase 1 Clinical	Nanjing Leadsbiolabs Co Ltd	Autoimmune Diseases; Lupus Erythematosus, Systemic	詳細