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CXCL1

CXCL1 製品リスト

  • 属性

    Protein (1)

  • 製品ライブラリ

    オンライン (1)

  • 種

    Human (1)

  • タグ

    Fc Tag (1)

  • マーカー

    Unconjugated (1)

製品番号種発現システム製品説明タンパク質の構造純度特性
CX1-H5253
Human
HEK293
Human CXCL1 Protein, Fc Tag (MALS verified)
総数量1
  • 1

CXCL1バックグランド

Chemokine (C-X-C motif) ligand 1 (CXCL1) is a small molecule of cytokines belonging to the CXC chemokine family. Also known as growth-regulated oncogene alpha (Growth-regulated oncogene alpha, GROα). It's also known as keratinocytes-derived chemokine (KC) in mice or cytokine-induced neutrophil chemoattractant type-1 (CINC-1) in rats. In humans, this protein is encoded by the gene Cxcl1 and is located on human chromosome 4 among genes for other CXC chemokines. The chemokine CXCL1 is expressed by macrophages, neutrophils and epithelial cells. The chemokine CXCL1 has a chemotactic effect on neutrophils. CXCL1 binds to the chemokine receptor CXCR2 and plays a role in cell chemotaxis. Human CXCL1 is clustered on chromosome 4 adjacent to many CXC chemokine genes. Major roles of CXCL1 include neovascularization, inflammation, wound healing, and tumorigenesis

治験薬に関する情報

英語名研究コード研究開発ステージ会社適応症臨床試験
HS-10241HS-10241Phase 3 ClinicalJiangsu Hansoh Pharmaceutical Group Co LtdSolid tumours; Carcinoma; Neoplasms; Carcinoma, Non-Small-Cell Lung
詳細
ZanzalintinibXL-092Phase 3 ClinicalExelixis IncSolid tumours; Leiomyosarcoma; Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Neoplasms; Carcinoma, Transitional Cell; Prostatic Neoplasms, Castration-Resistant; Breast Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular
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RefanalinANG-3777; BB-3; SNV-003Phase 3 ClinicalVifor Pharma Ag, Elicio TherapeuticsMyocardial Infarction; Pneumonia; Coronavirus Disease 2019 (COVID-19); Acute Kidney Injury; Delayed Graft Function
詳細
FosgonimetonATH-1017; NDX-1017Phase 3 ClinicalM3 BiotechnologyAlzheimer Disease; Lewy Body Disease
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SitravatinibMGCD-516; IND-155305; MGCD-0516; MG-91516; MG-516Phase 3 ClinicalBreast Neoplasms; Gastrointestinal Neoplasms; Carcinoma, Non-Small-Cell Lung; Uterine Cervical Neoplasms; Carcinoma, Hepatocellular; Endometrial Neoplasms; Lung Neoplasms; Metastatic breast cancer; Esophageal Squamous Cell Carcinoma; Mouth Neoplasms; Carcinoma, Squamous Cell; Hepatic Insufficiency; Ureteral Neoplasms; Solid tumours; Lung Diseases; Liposarcoma; Uveal melanoma; Triple Negative Breast Neoplasms; Carcinoma, Transitional Cell; Neoplasms; Carcinoma; Carcinoma, Renal Cell; Squamous Cell Carcinoma of Head and Neck; Kidney Neoplasms; Biliary Tract Neoplasms
詳細
HS-20117HS-20117; PM1080; PM-1080Phase 3 ClinicalBiotheus IncSolid tumours; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung
詳細
Telisotuzumab adizutecanABBV-400Phase 3 ClinicalAbbvie IncSolid tumours; Biliary Tract Neoplasms; Stomach Neoplasms; Squamous Cell Carcinoma of Head and Neck; Esophageal Neoplasms; Triple Negative Breast Neoplasms; Breast Neoplasms; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Esophageal Squamous Cell Carcinoma; Esophageal adenocarcinoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung
詳細
SC-0011SC-0011Phase 3 ClinicalShijiazhuang Zhikang Hongren New Drug Development Co LtdSolid tumours; Esophageal Neoplasms; Stomach Neoplasms; Carcinoma, Non-Small-Cell Lung
詳細
AL-2846AL-2846Phase 3 ClinicalAdvenchen Laboratories Nanjing LtdNeurofibromatoses; Neurilemmoma; Neurofibromatosis 1; Carcinoma, Non-Small-Cell Lung; Lung Neoplasms; Thyroid Neoplasms; Colorectal Neoplasms; Prostatic Neoplasms; Medullary thyroid cancer (MTC); Solid tumours; Neurofibroma; Ganglioglioma; Neoplasms; Pancreatic Neoplasms; Stomach Neoplasms; Liver Neoplasms; Ovarian Neoplasms; Bone metastases
詳細
Ningetinib TosylateCT-053-PTSA; CT-053Phase 2 ClinicalHec Pharm Co LtdIntestinal Neoplasms; Solid tumours; Carcinoma, Renal Cell; Stomach Neoplasms; Leukemia, Myeloid, Acute; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung
詳細
PamvatamigMCLA-129Phase 2 ClinicalMerus NvSolid tumours; Head and Neck Neoplasms; Stomach Neoplasms; Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms; Esophageal Squamous Cell Carcinoma; Carcinoma, Non-Small-Cell Lung
詳細
Merestinib5OGS5K699E; LY-2801653Phase 2 ClinicalEli Lilly And CompanyBiliary Tract Neoplasms; Skin Melanoma; Bone metastases; Solid tumours; Neoplasms; Pancreatic Neoplasms; Microsatellite instability-high cancer; Lymphoma, Mantle-Cell; Breast Neoplasms; Cholangiocarcinoma; Colorectal Neoplasms; Leukemia, Myeloid, Acute; Lymphoma, Non-Hodgkin; Gallbladder Neoplasms; Neoplasm Metastasis; Carcinoma, Non-Small-Cell Lung
詳細
Sym-015Sym-015Phase 2 ClinicalSymphogen A/SNeoplasms; Carcinoma, Non-Small-Cell Lung
詳細
ABN-401ABN-401; KDDF-201603-08Phase 2 ClinicalAbion IncSolid tumours; Neoplasms
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REGN-5093-M114METxMET-M114; REGN5093-M114Phase 2 ClinicalCarcinoma, Non-Small-Cell Lung
詳細
GlesatinibMGCD-265; MG-90265X; 7Q29OXD98N; MG-90265H9; MG-90265gly; MG-90265Phase 2 ClinicalNeoplasms; Carcinoma, Non-Small-Cell Lung
詳細
BafisontamabFIT-013a; EMB-01Phase 2 ClinicalShanghai Epimab Biotherapeutics, IncBiliary Tract Neoplasms; Liver Neoplasms; Carcinoid Tumor; Stomach Neoplasms; Neoplasms; Digestive System Neoplasms; Colorectal Neoplasms; Lung Neoplasms; Neoplasm Metastasis; Gastrointestinal Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular
詳細
GB-263GB-263; GB-263TPhase 2 ClinicalGenor Biopharma Co LtdSolid tumours; Neoplasms; Carcinoma, Non-Small-Cell Lung
詳細
ElzovantinibTPX-0022Phase 2 ClinicalTurning Point Therapeutics IncSolid tumours; Stomach Neoplasms; Carcinoma, Non-Small-Cell Lung; Neoplasm Metastasis
詳細
PRO-1286PRO-1286; GEN1286; GEN-1286Phase 2 ClinicalProfoundBio (Suzhou) Co LtdSolid tumours; Neoplasms
詳細
Do-1Do-1Phase 2 ClinicalDeuterOncology NVLung Neoplasms
詳細
EMI-137EMI-137; GE-137Phase 2 ClinicalGe HealthcareEsophageal Neoplasms; Extranodal Extension; Colonic Neoplasms; Barrett Esophagus
詳細
DavutamigREGN-5093Phase 2 ClinicalCarcinoma, Non-Small-Cell Lung
詳細
CKD-702Phase 2 ClinicalChong Kun Dang Pharmaceutical CorpStomach Neoplasms; Carcinoma, Non-Small-Cell Lung
詳細
Recombinant adenovirus-hepatocyte growth factor(Institute Of Radiation And Radiation Medicine, Chinese Academy Of Military Medical Sciences)Phase 2 ClinicalInstitute Of Radiation And Radiation Medicine, Chinese Academy Of Military Medical Sciences, Beijing Haitai United Pharmaceutical Technology Development Co LtdMyocardial Ischemia
詳細
RC-108RC-108; RC108Phase 2 ClinicalRemeGen Co LtdSolid tumours; Digestive System Neoplasms; Gastrointestinal Neoplasms; Carcinoma, Non-Small-Cell Lung
詳細
EmibetuzumabLA-480; LY-2875358Phase 2 ClinicalEli Lilly And CompanySolid tumours; Carcinoma, Renal Cell; Esophageal Neoplasms; Stomach Neoplasms; Neoplasms; Lymphoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular
詳細
SHR-A1403SHR-A1403Phase 1 ClinicalSolid tumours
詳細
CM-118CM-118Phase 1 ClinicalXcoveryNeoplasms; Carcinoma, Non-Small-Cell Lung
詳細
KanitinibCX-1003Phase 1 ClinicalBeijing Konruns Pharmaceutical Co Ltd, Guangzhou Yingsheng Bio Technology Co LtdSolid tumours
詳細
BPI-9016BPI-9016; BPI-9016MPhase 1 ClinicalBetta Pharmaceuticals Co LtdSolid tumours; Carcinoma, Non-Small-Cell Lung
詳細
HLX-55HLX-55; KTN-0216Phase 1 ClinicalKolltan Pharmaceuticals IncSolid tumours
詳細
PamufetinibTAS-115Phase 1 ClinicalTaiho Pharmaceutical Co Ltd, Otsuka Pharmaceutical Co LtdNeoplasms
詳細
Boxitinib HydrochloridePhase 1 ClinicalHec Pharm Co LtdStomach Neoplasms; Carcinoma, Renal Cell; Breast Neoplasms; Glioma; Lung Neoplasms
詳細
BYON-3521BYON-3521Phase 1 ClinicalByondis BvSolid tumours; Neoplasms
詳細
ATH-1020ATH-1020Phase 1 ClinicalAthira Pharma Inc
詳細
QBH-196QBH-196Phase 1 ClinicalShenyang Pharmaceutical UniversitySolid tumours; Stomach Neoplasms
詳細
BG-T187BG-T187; BGT187Phase 1 ClinicalSolid tumours; Lung Neoplasms; Gastrointestinal Neoplasms
詳細
[11C]savolitinib[11C]savolitinibPhase 1 ClinicalAstrazeneca Plc
詳細
[14C]HS-10241[14C]HS-10241Phase 1 ClinicalJiangsu Hansoh Pharmaceutical Group Co LtdCarcinoma, Non-Small-Cell Lung
詳細
ABBV-303ABBV-303; DF-4101Phase 1 ClinicalDragonfly Therapeutics LlcSolid tumours
詳細
FPI-2107[111In]-FPI-2107Phase 1 ClinicalSolid tumours; Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung
詳細
FPI-2053FPI-2053Phase 1 ClinicalAstrazeneca PlcSolid tumours; Squamous Cell Carcinoma of Head and Neck; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung
詳細
DM-005DM-005; DM005Phase 1 ClinicalDoma Biopharmaceutical (Suzhou) Co LtdSolid tumours; Squamous Cell Carcinoma of Head and Neck; Carcinoma, Non-Small-Cell Lung
詳細
ANS-014004ANS014004; ANS-014004; ANS-01; ANS01Phase 1 ClinicalSolid tumours; Neoplasms
詳細
FPI-2068[225Ac]-FPI-2068; FPI-2068Phase 1 ClinicalAstrazeneca PlcSolid tumours; Squamous Cell Carcinoma of Head and Neck; Neoplasms; Colorectal Neoplasms; Carcinoma, Pancreatic Ductal; Carcinoma, Non-Small-Cell Lung
詳細
SPH-3348SPH-3348; SPH3348; I-020Phase 1 ClinicalShanghai Pharmaceuticals Holding Co LtdSolid tumours; Neoplasms
詳細
MYTX-011MYTX-011Phase 1 ClinicalMythic Therapeutics IncCarcinoma, Non-Small-Cell Lung
詳細
AZD9592AZD-9592; AZD9592Phase 1 ClinicalAstrazeneca PlcSolid tumours; Head and Neck Neoplasms; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung
詳細
TAVO-412TAVO-412Phase 1 ClinicalTavotek Biotherapeutics (Hong Kong) Ltd, Tuochuang Biotechnology (Jiangsu) Co LtdSolid tumours; Neoplasms
詳細
NP-107NP107; NP-107Phase 1 ClinicalShanghai Nawei Biotechnology Co LtdSolid tumours
詳細
ASKC-202ASKC202Phase 1 ClinicalJiangsu Aosaikang Pharmaceutical Co LtdSolid tumours; Carcinoma, Non-Small-Cell Lung
詳細
LMV-12(HE003)LMV-12(HE003)Phase 1 ClinicalNanchang Hongyi Technology Co LtdSolid tumours
詳細
GST-HG161GST-HG161Phase 1 ClinicalFujian Cosunter Pharmaceutical Co LtdSolid tumours; Neoplasms; Carcinoma, Hepatocellular
詳細
Metatinib TrometamolBMS-817378; SIM-817378Phase 1 ClinicalBristol-Myers Squibb CompanySolid tumours; Liver Neoplasms; Stomach Neoplasms; Colorectal Neoplasms
詳細
NP-01 (Shijiazhuang No.4 Pharmaceutical/Nanjing Nadingfei Medical Technology)NP-01Phase 1 ClinicalShijiazhuang No 4 Pharmaceutical Co Ltd, Nanjing Nadingfei Pharmaceutical Technology Co LtdSolid tumours; Liver Neoplasms; Stomach Neoplasms; Lung Neoplasms
詳細
SAIT-301SAIT-301Phase 1 ClinicalSamsung Medical CenterNeoplasms
詳細
NPS-1034HOPE-777; KDDF-201111-02Neopharma Ltd
詳細

市販薬剤に関する情報

英語名研究コード研究開発ステージ会社オリジナル製品名最初に承認をした国最初の適応症最初に承認を受けた会社承認された日付適応症臨床試験
CrizotinibPF-1066; PF-2341066; PF-02341066; PF-002341066ApprovedPfizer Inc赛可瑞, XalkoriUnited StatesCarcinoma, Non-Small-Cell LungPf Prism Cv2011-08-26Urethral Neoplasms; Neoplasm Metastasis; Adenocarcinoma; Neurilemmoma; Carcinoma, Non-Small-Cell Lung; Lung Neoplasms; Granuloma, Plasma Cell; Endometrial Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lymphoma; Ureteral Neoplasms; Solid tumours; Lymphoma, Primary Cutaneous Anaplastic Large Cell; Neuroblastoma; Urinary Bladder Neoplasms; Myofibroma; Uveal melanoma; Multiple Myeloma; Neurofibromatosis 2; Neoplasms; Renal Insufficiency; Hematologic Neoplasms
詳細
UnecritinibTQ-B3101; TTQ-B3101ApprovedSoutheast University安柏尼Mainland ChinaCarcinoma, Non-Small-Cell LungJiangsu Chia Tai-Tianqing Pharmaceutical Co Ltd2024-04-24Stomach Neoplasms; Neoplasms; Lymphoma, Large-Cell, Anaplastic; Lymphoma; Carcinoma, Non-Small-Cell Lung
詳細
GlumetinibHH-SCC244; SCC244; SCC-244ApprovedShanghai Institute Of Materia Medica, Chinese Academy Of Sciences, Shanghai Greenvalley Pharmaceutical Co Ltd海益坦Mainland ChinaCarcinoma, Non-Small-Cell LungShangHai HaiHe Biopharma Co Ltd2023-03-07Solid tumours; Carcinoma, Non-Small-Cell Lung
詳細
Tepotinib hydrochloride hydrateMSC-2156119J; MSC-2156119; EMD-1214063ApprovedMerck SeronoTepmetko, テプミトコ, TEPMETKOJapanCarcinoma, Non-Small-Cell LungMerck KGaA, Darmstadt, Germany2020-03-25Solid tumours; Colorectal Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Hepatocellular
詳細
Capmatinib HydrochlorideINCB-28060; C2A374O70X; INC-280; INCB-028060; NVP-INC280-NXApprovedIncyte Corp, Novartis Pharma AgTabrectaUnited StatesCarcinoma, Non-Small-Cell LungNovartis Pharmaceuticals Corp2020-05-06Adenocarcinoma of Lung; Neoplasm Metastasis; Carcinoma, Hepatocellular; Melanoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Gliosarcoma; Colorectal Neoplasms; Sarcoma; Solid tumours; Neoplasms; Triple Negative Breast Neoplasms; Glioblastoma; Carcinoma; Carcinoma, Renal Cell; Kidney Neoplasms; Liver Neoplasms
詳細
SavolitinibHM-5016504; AZD-6094; HMP-504; HMPL-504ApprovedHutchison Medipharma Ltd沃瑞沙, ORPATHYSMainland ChinaCarcinoma, Non-Small-Cell LungHutchison Medipharma Ltd2021-06-22Central Nervous System Neoplasms; Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Lung Neoplasms; Neoplasms, Neuroepithelial; Glioma; Carcinoma, Squamous Cell; Urologic Neoplasms; Diffuse Intrinsic Pontine Glioma; Colorectal Neoplasms; Peritoneal Neoplasms; Cholangiocarcinoma; Medulloblastoma; Kidney Diseases; Colonic Neoplasms; Neoplasms; Carcinoma; Stomach Neoplasms; Esophageal Neoplasms; Rectal Neoplasms; Carcinoma, Renal Cell; Kidney Neoplasms; Solid tumours
詳細
Ensartinib HydrochlorideX-396ApprovedXcovery贝美纳Mainland ChinaCarcinoma, Non-Small-Cell LungBetta Pharmaceuticals Co Ltd2020-11-17Sarcoma; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Xanthogranuloma, Juvenile; Neuroectodermal Tumors, Primitive, Peripheral; Neoplasms, Germ Cell and Embryonal; Neoplasms, Neuroepithelial; Brain metastases; Carcinoma, Squamous Cell; Glioma; Lymphoma, Non-Hodgkin; Lung Neoplasms; Histiocytic Sarcoma; Neuroblastoma; Solid tumours; Histiocytosis, Langerhans-Cell; Osteosarcoma; Sarcoma, Ewing; Central Nervous System Neoplasms; Neoplasms; Small Cell Lung Carcinoma; Wilms Tumor; Rhabdoid Tumor; Hepatoblastoma; Medulloblastoma; Ependymoma; Rhabdomyosarcoma
詳細
AmivantamabJNJ-61186372; JNJ-372; JNJ-6372; CNTO4424; CNTO-4424ApprovedGenmab A/S, Johnson & Johnson Innovative MedicineRYBREVANTUnited StatesCarcinoma, Non-Small-Cell LungJanssen Biotech Inc2021-05-21Solid tumours; Esophageal Neoplasms; Stomach Neoplasms; Glioblastoma; Carcinoma, Adenoid Cystic; Colorectal Neoplasms; Glioma; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Adenocarcinoma; Carcinoma, Hepatocellular
詳細
Cabozantinib S-malateXL-184; BMS-907351; RO7047650; RO-7047650ApprovedExelixis IncCometriq, CabometyxUnited StatesThyroid Neoplasms; Carcinoma, NeuroendocrineExelixis Inc2012-11-29Neuroblastoma; Thyroid Neoplasms; Hepatic Insufficiency; Astrocytoma; Peritoneal Neoplasms; Bile Duct Neoplasms; Colorectal Neoplasms; Gliosarcoma; Urethral Neoplasms; Sarcoma, Clear Cell; Uterine Neoplasms; Cholangiocarcinoma; Neurofibroma, Plexiform; Brain Neoplasms; Adenocarcinoma, Clear Cell; Carcinoma, Adenosquamous; Medullary thyroid cancer (MTC); Sarcoma, Ewing; Sarcoma; Osteosarcoma; Sarcoma, Alveolar Soft Part; Neoplasm Metastasis; Melanoma; Carcinoma, Non-Small-Cell Lung; Carcinoma, Endometrioid; Thyroid Cancer, Papillary; Meningioma; Paraganglioma; Neoplasms, Germ Cell and Embryonal; Carcinoma, Hepatocellular; Prostatic Neoplasms; Glioma; Brain metastases; Endometrial Neoplasms; Leukemia, Myeloid, Acute; Carcinoma, Squamous Cell; Lymphoma; Carcinoma, Neuroendocrine; Fallopian Tube Neoplasms; Carcinoma, Renal Cell; Adenoma, Islet Cell; Glioblastoma; Carcinoma, Ovarian Epithelial; Renal Insufficiency; Hepatoblastoma; Pheochromocytoma; Carcinoid Tumor; Carcinoma, Merkel Cell; Rejection of liver transp
詳細
VebreltinibPLB-1001; CBT-101; APL-101; CBI-3103ApprovedCrown Bioscience IncMainland ChinaCarcinoma, Non-Small-Cell LungBeijing Purunao Biotechnology Co Ltd2023-11-16Colonic Neoplasms; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Glioma; Thyroid Neoplasms; Lung Neoplasms; Hepatic Insufficiency; Astrocytoma; Brain Neoplasms; Solid tumours; Glioblastoma; Pancreatic Neoplasms; Ganglioglioma; Neoplasms; Carcinoma, Renal Cell; Stomach Neoplasms; Esophageal Neoplasms; Kidney Neoplasms
詳細
  • 製品リスト
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  • 治験薬に関する情報
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