言語を選択

DLL1

DLL1 詳細

英語名	Delta Like Canonical Notch Ligand 1	市販薬剤の数	0
治験薬の数	0	ターゲットの別称	Delta Like Canonical Notch Ligand 1，Drosophila Delta Homolog 1，Delta-Like Protein 1，H-Delta-1，Epididymis Secretory Sperm Binding Protein，Delta (Drosophila)-Like 1，Delta-Like 1 (Drosophila)，DELTA1，NEDBAS，Delta1，Delta，DL1，Drosophila Delta homolog 1 (Delta1; H-Delta-1)
研究＆開発段階	Preclinical

英語名	Delta Like Canonical Notch Ligand 1
ターゲットの別称	Delta Like Canonical Notch Ligand 1，Drosophila Delta Homolog 1，Delta-Like Protein 1，H-Delta-1，Epididymis Secretory Sperm Binding Protein，Delta (Drosophila)-Like 1，Delta-Like 1 (Drosophila)，DELTA1，NEDBAS，Delta1，Delta，DL1，Drosophila Delta homolog 1 (Delta1; H-Delta-1)
市販薬剤の数	0
治験薬の数	0
研究＆開発段階	Preclinical

DLL1 製品リスト

属性
Protein (3)Cell Grade Beads (2)
製品ライブラリ
オンライン (5)
種
Human (3)- (2)
タグ
His Tag (1)His Tag & Avi Tag (1)- (2)Fc Tag (1)
マーカー
Unconjugated (2)Biotin-labeled (1)- (2)

製品番号	種	発現システム	製品説明
HOT DL1-H52H8	Human	HEK293	Human DLL1 / Delta1 Protein, His Tag, premium grade
HOT DL1-H82E5	Human	HEK293	Biotinylated Human DLL1 / Delta1 Protein, His,Avitag™, premium grade
HOT MBS-C040	-	-	ActiveMax® Human DLL1 μBeads, premium grade (for cells, 5.5μm)
DL1-H5259	Human	HEK293	Human DLL1 / Delta1 Protein, Fc Tag, premium grade
MBS-C041	-	-	ActiveMax® Human DLL1 μBeads, premium grade (for cells, 20 μm)

総数量5

DLL1バックグランド

Delta-like protein 1 (DLL1) is also known as Drosophila Delta homolog 1 (Delta1 or H-Delta-1), which contains one DSL domain and eight EGF-like domains. DLL1 is ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation. As for expression, DLL1 is expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney. Furthermore, DLL1 acts as a ligand for Notch receptors. Also, DLL1 can block the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.